Results 31 to 40 of about 55,724 (327)

The accuracy, feasibility and challenges of sequencing short tandem repeats using next-generation sequencing platforms. [PDF]

PLoS ONE, 2014
To date we have little knowledge of how accurate next-generation sequencing (NGS) technologies are in sequencing repetitive sequences beyond known limitations to accurately sequence homopolymers.
Monika Zavodna, Andrew Bagshaw, Rudiger Brauning, Neil J Gemmell   +3 more
doaj   +1 more source

Genetic diversity of peanut (Arachis hypogaea L.) and its wild relatives based on the analysis of hypervariable regions of the genome [PDF]

, 2004
BACKGROUND: The genus Arachis is native to a region that includes Central Brazil and neighboring countries. Little is known about the genetic variability of the Brazilian cultivated peanut (Arachis hypogaea, genome AABB) germplasm collection at the DNA ...
Ferreira, Marcio Elias, Hopkins, Mark S, Kresovich, Stephen, Mitchell, Sharon E, Moretzsohn, Marcio de Carvalho, Valls, Jose Francisco Montenegro   +5 more
core   +4 more sources

Molecular karyotyping of Siberian wild rye (Elymus sibiricus L.) with oligonucleotide fluorescence in situ hybridization (FISH) probes.

PLoS ONE, 2020
Siberian wild rye (Elymus sibiricus L.), an allotetraploid species, is a potentially high-quality perennial forage crop native to temperate regions. We used fluorescently conjugated oligonucleotides, representing ten repetitive sequences, including 6 ...
Jihong Xie, Yan Zhao, Linqing Yu, Ruijuan Liu, Quanwen Dou   +4 more
doaj   +1 more source

Identification and validation of microsatellite markers in strawberry tree (Arbutusunedo L.) [PDF]

, 2019
Strawberry tree (Arbutus unedo L.), an evergreen shrub/small tree of the family Ericaceae, is a main constituent of the Mediterranean basin flora; although it is also found in southwestern Prance, Macaronesia, and Ireland. The small fruits are edible but
Carlier, Jorge, Fazenda, Pedro, Fonseca, Maria, Leitão, José, Pereira, Ricardo   +4 more
core   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

Hepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou, Yongkun Sun, Wen Zhang, Jiajia Yuan, Zhi Peng, Wei Wang, Jifang Gong, Lin Yang, Yanshuo Cao, Hong Zhao, Chao Chen, Weifeng Wang, Lin Shen, Aiping Zhou   +13 more
wiley   +1 more source

Rapid development of gene-tagged microsatellite markers from bacterial artificial chromosome clones using anchored TAA repeat primers

BioTechniques, 2003
We developed a technique to improve the efficiency of producing TAA repeat microsatellite markers linked to interspecific conserved genes. Template DNA was prepared from cultures derived from single bacterial artificial chromosome (BAC) colonies using a ...
Geoffrey C. Waldbieser, Sylvie M.A. Quiniou, Attila Karsi   +2 more
doaj   +1 more source

Molecular cytogenetic differentiation of paralogs of Hox paralogs in duplicated and re-diploidized genome of the North American paddlefish (Polyodon spathula). [PDF]

, 2017
BackgroundAcipenseriformes is a basal lineage of ray-finned fishes and comprise 27 extant species of sturgeons and paddlefishes. They are characterized by several specific genomic features as broad ploidy variation, high chromosome numbers, presence of ...
Amemiya, Chris T, Flajšhans, Martin, Gela, David, Havelka, Miloš, Howell, William Mike, Kořínková, Tereza, Ráb, Petr, Symonová, Radka   +7 more
core   +4 more sources

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

Microsatellite development from genome skimming and transcriptome sequencing: comparison of strategies and lessons from frog species

BMC Genomics, 2018
Background Even though microsatellite loci frequently have been isolated using recently developed next-generation sequencing (NGS) techniques, this task is still difficult because of the subsequent polymorphism screening requires a substantial amount of ...
Yun Xia, Wei Luo, Siqi Yuan, Yuchi Zheng, Xiaomao Zeng   +4 more
doaj   +1 more source

Clinical and mechanism research progress on short tandem repeat ⁃ related neuromuscular diseases

Chinese Journal of Contemporary Neurology and Neurosurgery, 2023
Short tandem repeat (STR) is a component of the human genome, the number of repeats of STR is prone to change during DNA replication, and when it exceeds a certain threshold, it will lead to the occurrence of diseases, most of which involve the nervous ...
WAN Ya‑lan, YU Jia‑xi, DENG Jian‑wen, HONG Dao‑jun, WANG Zhao‑xia   +4 more
doaj   +1 more source