Results 131 to 140 of about 51,470 (255)

Microsatellites [PDF]

Communications in Asteroseismology, 2007
openaire   +2 more sources

A Spotlight on Yolk‐sac Tumors: Molecular Pathology, Current Diagnostics, and Novel Therapeutics

Andrology, EarlyView.
ABSTRACT Background Yolk‐sac tumors are an aggressive subtype of testicular cancer that significantly contribute to disease progression and therapy resistance, especially in adults. While testicular cancer generally has high cure rates with cisplatin‐based treatment, adult yolk‐sac tumors often appear as components of mixed tumors with poor response to
Evangelos Prokakis, Lisa Schneider, Felix Bremmer, Daniel Nettersheim   +3 more
wiley   +1 more source

<i>Canis</i> STR-Seq: A Universal Approach for Non-Invasive Genetic Monitoring of Wolves and Coyotes. [PDF]

Ecol Evol
Walker E, Patterson BR, Rutledge GA, Rutledge LY.   +3 more
europepmc   +1 more source

Wise or Wide? Rethinking Surgical Margins for Melanoma. [PDF]

Dermatol Pract Concept
Paoli J.
europepmc   +1 more source

Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki, Annamari T. Immonen, Joel T. Rämö, Aino M. Jaakkola, Kari Krootila, Maria Kaukonen, FinnGen, Aarno Palotie, Hannes Lohi, Tero T. Kivelä, Joni A. Turunen   +10 more
wiley   +1 more source

Comparative Genomic Analysis of Coding Sequence-Derived Microsatellites Reveals Evolutionary Conservation and Genetic Diversity in Forest Musk Deer (<i>Moschus berezovskii</i>) and Related Ruminants. [PDF]

Vet Sci
Dong ZJ, Ren YY, Qi WH.
europepmc   +1 more source

Dystrophia Smolandiensis is characterized by a novel NQO1 variant and a distinct phenotype from COL17A1‐associated epithelial recurrent erosion dystrophy

Acta Ophthalmologica, EarlyView.
Abstract Purpose To determine the molecular cause of the two epithelial recurrent erosion dystrophies, Dystrophia Smolandiensis and Dystrophia Helsinglandica, and to identify phenotypic differences between the two conditions. Methods DNA samples and clinical data from structured interview records were obtained from the Swedish families in which ...
Karl De Geer, Kristina Lagerstedt‐Robinson, Daniel Nilsson, Cilla Söderhäll, Björn Hammar, Erik Björck   +5 more
wiley   +1 more source

A yeast recombination system recapitulates the length polymorphism of a microsatellite implicated in human social behavior. [PDF]

NAR Mol Med
Kean CE, Radchenko EA, Lindenbaum NM, Materne G, Mirkin SM.   +4 more
europepmc   +1 more source

Lack of Population Structure of an Extreme Migratory Shorebird: Evidence of Gene Flow Between Geographically Disparate Populations. [PDF]

Ecol Evol
Gherardi-Fuentes C, Ruiz J, Senner NR, Johnson JA, Masero JA, Gutiérrez J, Verdugo C, Navedo JG.   +7 more
europepmc   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source