Results 61 to 70 of about 211,987 (323)

Implicit Methods for Equation-Free Analysis: Convergence Results and Analysis of Emergent Waves in Microscopic Traffic Models [PDF]

, 2014
We introduce a general formulation for an implicit equation-free method in the setting of slow-fast systems. First, we give a rigorous convergence result for equation-free analysis showing that the implicitly defined coarse-level time stepper converges ...
Berkemer, Rainer, Kawamoto, Atsushi, Marschler, Christian, Sieber, Jan, Starke, Jens   +4 more
core   +2 more sources

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

FEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito, Masashi Arakawa, Koki Maeda, Eiji Morita   +3 more
wiley   +1 more source

An Open-Source Microscopic Traffic Simulator

, 2010
We present the interactive Java-based open-source traffic simulator available at www.traffic-simulation.de. In contrast to most closed-source commercial simulators, the focus is on investigating fundamental issues of traffic dynamics rather than ...
Kesting, Arne, Treiber, Martin
core   +1 more source

Using Smart Traffic Lights to Reduce CO2 Emissions and Improve Traffic Flow at Intersections: Simulation of an Intersection in a Small Portuguese City

Applied System Innovation, 2023
Reducing CO2 emissions is currently a key policy in most developed countries. In this article, we evaluate whether smart traffic lights can have a relevant role in reducing CO2 emissions in small cities, considering their specific traffic profiles.
O. Santos, F. Ribeiro, J. Metrôlho, Rogério Dionísio   +3 more
semanticscholar   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Kinetic derivation of a Hamilton-Jacobi traffic flow model

, 2012
Kinetic models for vehicular traffic are reviewed and considered from the point of view of deriving macroscopic equations. A derivation of the associated macroscopic traffic flow equations leads to different types of equations: in certain situations ...
Borsche, Raul, Kimathi, Mark, Klar, Axel
core   +1 more source

Demand Data Modelling for Microscopic Traffic Simulation

Transport and Telecommunication, 2018
The current paper aim is to present the technique of demand data modelling for microscopic simulation of the traffic flows. Traffic microscopic simulation is a powerful decision supporting tool, which could be applied for a wide range of tasks. In a past
Savrasovs Mihails, Pticina Irina, Zemlyanikin Valery, Karakikes Ioannis   +3 more
doaj   +1 more source

Human behavior as origin of traffic phases

, 2001
It is shown that the desire for smooth and comfortable driving is directly responsible for the occurrence of complex spatio-temporal structures (``synchronized traffic'') in highway traffic. This desire goes beyond the avoidance of accidents which so far
Andreas Schadschneider, B.S. Kerner, B.S. Kerner, B.S. Kerner, B.S. Kerner, C. Appert, D. Chowdhury, D. Helbing, F.L. Hall, H.Y. Lee, K. Nagel, L. Neubert, Ludger Santen, M. Rickert, Michael Schreckenberg, P. Nelson, R. Barlovic, V. Popkov, W. Knospe, Wolfgang Knospe   +19 more
core   +1 more source