Results 51 to 60 of about 73,898 (290)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Estimate of traffic emissions through multiscale second order models with heterogeneous data

open access: yesNetworks and Heterogeneous Media, 2022
In this paper we propose a multiscale traffic model, based on the family of Generic Second Order Models, which integrates multiple trajectory data into the velocity function.
Caterina Balzotti, Maya Briani
doaj   +1 more source

Microscopic traffic models, accidents, and insurance losses

open access: yesASTIN Bulletin
AbstractThe paper develops a methodology to enable microscopic models of transportation systems to be accessible for a statistical study of traffic accidents. Our approach is intended to permit an understanding not only of historical losses but also of incidents that may occur in altered, potential future systems. Through such a counterfactual analysis,
Sojung Kim, Marcel Kleiber, Stefan Weber
openaire   +2 more sources

On the Microscopic Modeling of Vehicular Traffic on General Networks [PDF]

open access: yesSIAM Journal on Applied Mathematics, 2020
15 ...
Rinaldo M. Colombo   +2 more
openaire   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Integrating micro and macro traffic control for mixed autonomy traffic

open access: yesCommunications in Transportation Research
During the transition to fully autonomous traffic systems, managing mixed traffic consisting of connected automated vehicles (CAVs) and human-driven vehicles (HDVs) is imperative.
Tingting Fan, Jieming Chen, Edward Chung
doaj   +1 more source

Agent-based modelling of air transport demand [PDF]

open access: yes, 2013
Constraints such as opening hours or passenger capacities influence travel options that can be offered by an airport and by the connecting airlines. If infrastructure, policy or technological measures modify transport options, then the benefits do not ...
Grether, Dominik, Nagel, Kai
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Steady state solutions of hydrodynamic traffic models

open access: yes, 2004
We investigate steady state solutions of hydrodynamic traffic models in the absence of any intrinsic inhomogeneity on roads such as on-ramps. It is shown that typical hydrodynamic models possess seven different types of inhomogeneous steady state ...
B.S. Kerner   +49 more
core   +1 more source

Comparison of homogeneous and heterogeneous motorised traffic at signalised and two-way stop control single lane intersection [PDF]

open access: yes, 2006
Results of a microscopic model of mixed motorised traffic consisting of short vehicles, (e.g. cars), and long vehicles, (taken to be double the length of the short vehicles), for an urban two-way single lane intersection are presented here.
R. Wang   +4 more
core   +1 more source

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