Results 161 to 170 of about 63,034 (211)

FRACTIONATION OF MOUSE LIVER MICROSOMAL ESTERASES

Canadian Journal of Biochemistry, 1965
Mouse liver microsomal esterases were fractionated on DEAE-cellulose after the solution of these enzymes in a solution containing 0.1 M glycyl glycine buffer, pH 7.0, and 5 × 10−4 M Lubrol W, a nonionic detergent. Elution of the enzymes from the DEAE-cellulose was accomplished by using NaCl in the glycyl glycine – Lubrol W solution.
C, CARRUTHERS, E, HEINS, A, BAUMLER
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A microsomal exoribonuclease from rat liver

Biochimica et Biophysica Acta (BBA) - Enzymology, 1979
A exoribonuclease has been purified from the microsomes of rat liver. The enzyme had an apparent molecular weight of 80 000-83 000 and produced, via a processive mechanism, 5'-AMP as the only product from poly(A). The degradation was found to proceed in the 3' to 5' direction.
H, Kumagai, K, Igarashi, K, Tanaka, H, Nakao, S, Hirose   +4 more
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Lipid peroxidation of rat liver microsomes

Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1980
1. The NADPH-dependent lipid peroxidation process was studied with microsomes and also the effects of addition of superoxide dismutase, catalase and thiourea. Only catalase and thiourea were able to inhibit lipid peroxidation. It seems that the initiating radical is the OH. radical formed by the Fenton reaction. 2.
J F, Koster, R G, Slee
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Mannosyltransfer reactions in rabbit liver microsomes

Biochemical and Biophysical Research Communications, 1976
Abstract Rabbit liver microsomes catalyzed mannosyltransfer from GDP-[14C]mannose to free D -mannose resulting in the synthesis of α-1,2-, α-1,3-, and α-1,6-mannosyl-mannose. Whereas formation of α-1,2-mannosyl-mannose was stimulated by the addition of manganese chloride or nickel chloride and was inhibited by EDTA, synthesis of α-1,3-mannosyl ...
J S, Schutzbach, A K, Verma
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Phosphatidylcholine mobility in liver microsomal membranes

Biochimica et Biophysica Acta (BBA) - Biomembranes, 1978
Purified phosphatidylcholine exchange protein from bovine liver was used to exchange rat liver microsomal phosphatidylcholine for egg phosphatidylcholine. It was found that at 25 and 37 degrees C rat liver microsomal phosphatidylcholine was completely and rapidly available for replacement by egg phosphatidylcholine.
A M, van den Besselaar, B, de Druijff, H, van den Bosch, L L, van Deenen   +3 more
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Reversible inactivation of liver microsomal pyrophosphatese

Life Sciences, 1972
Abstract Rat liver microsomes lost their pyrophosphatase activity in a pH and temperature dependent reaction. Peroxidation of microsomal lipids did not appear to be required as inactivation occured in the absence of measurable lipid peroxidation. The pH of the media affected the final extent of enzyme inactivation.
G W, Rafter, B H, Witherspoon
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Gliclazide hydroxylation by rat liver microsomes

Xenobiotica, 1995
1. The metabolism of gliclazide to hydroxygliclazide has been investigated in Sprague-Dawley rat liver microsomes. 2. The kinetics of hydroxygliclazide formation are consistent with Michaelis-Menten kinetics (mean (+/- SD, n = 3) apparent K(m) and Vmax = 256 +/- 27 microM and 1.85 +/- 0.10 nmol/ min/mg respectively). 3.
A, Rieutord, I, Stupans, G M, Shenfield, A S, Gross   +3 more
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Interaction of ranitidine with liver microsomes

Xenobiotica, 1982
1. Ranitidine interacts with liver microsomes from rats pretreated with different inducers of cytochrome P-450 to produce substrate difference optical spectra with a peak at 426-429 nm and a trough at 390-400 nm. 2. Cytochrome P-450 reduced with dithionite in the presence of ranitidine produced substrate difference spectra with a peak at 447 nm. 3.
S, Rendić, T, Alebić-Kolbah, F, Kajfez, H H, Ruf   +3 more
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Microsomal monooxygenase system in frog livers

Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1984
Liver microsomes prepared from four species of frog, Rana catesbeiana, Rana nigromaculata , Bufo bufo japonicus, and Xenopus laevis, contained cytochrome P-450 and showed NAD(P)H-dependent monooxygenase activities to several foreign chemical compounds tested.
M, Noshiro, T, Omura
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Benzene metabolism in mouse liver microsomes

Toxicology and Applied Pharmacology, 1973
Abstract Mouse liver microsomes metabolized benzene more rapidly than microsomes prepared from rat and rabbit liver. Treatment of mice with benzene increased the metabolism of benzene in vitro without increasing cytochrome P-450 concentrations. Conversely, treatment of mice with phenobarbital increased cytochrome P-450 values but did not increase ...
L M, Gonasun, C, Witmer, J J, Kocsis, R, Snyder   +3 more
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