Results 111 to 120 of about 97,218 (302)
Über den Steringehalt pflanzlicher Mikrosomen
The composition of microsomal lipids from Spirodela oligorrhiza L., Lactuca sativa L., and Allium porrum L. plants was investigated. Contamination by chloroplast lipids was calculated and eliminated, giving the lipids of “chloroplast-free microsomes ...
W. Eichenberger
doaj +1 more source
Metabolism of Epoxidised Withanolides by a Generalist and a Specialist Insect Species
Larvae of Heliothis (Chloridea) virescence and subflexa have the ability to convert the epoxidized terpenoid 4β‐hydroxywithanolide E (4BHWE) to withanolide S. The conversion is found by feeding the larvae an artificial diet supplemented with 13C‐labeled 4BHWE.
Marie Pauline Sell +4 more
wiley +1 more source
Biochemical research elucidating metabolic pathways in Pneumocystis*
Advances in sequencing the Pneumocystis carinii genome have helped identify potential metabolic pathways operative in the organism. Also, data from characterizing the biochemical and physiological nature of these organisms now allow elucidation of ...
Kaneshiro E.S.
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The breakdown of adenosine triphosphate accompanying cholic acid activation by guinea-pig liver microsomes [PDF]
William H. Elliott
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Abstract Ritonavir (RTV) is a potent CYP3A inhibitor that is widely used as a pharmacokinetic (PK) enhancer to increase exposure to select protease inhibitors. However, as a strong and complex perpetrator of CYP3A interactions, RTV can also enhance the exposure of other co‐administered CYP3A substrates, potentially causing toxicity.
Lien Thi Ngo +5 more
wiley +1 more source
3-Hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the enzyme catalyzing the rate-limiting step in cholesterol biosynthesis, exists in one active (dephosphorylated) and one inactive (phosphorylated) form in liver microsomes obtained from several ...
B Angelin +4 more
doaj +1 more source
Factors influencing the incorporation of amino acid into the protein of microsome and mitochondria preparations of rat liver and liver tumour [PDF]
Olga Greengard, P.N. Campbell
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ABSTRACT Efavirenz induces and inhibits multiple drug‐metabolizing enzymes, contributing to significant drug–drug interactions. This study quantified the impact of multiple doses of efavirenz on CYP3A activity via midazolam metabolism using a population pharmacokinetic approach.
Kimberly S. Collins +6 more
wiley +1 more source
Pyridine nucleotide regulation of hepatic endoplasmic reticulum calcium uptake
Pyridine nucleotides serve an array of intracellular metabolic functions such as, to name a few, shuttling electrons in enzymatic reactions, safeguarding the redox state against reactive oxygen species, cytochrome P450 (CYP) enzyme detoxification ...
Xudong Wang +2 more
doaj +1 more source
Fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in rat testicles
A comparative study was made on the fate of linoleic, arachidonic, and docosa-7,10,13,16-tetraenoic acids in various subcellular fractions of liver and testis from rats of different ages.
Sixta Ayala +4 more
doaj +1 more source

