Results 171 to 180 of about 81,174 (219)

Conformational Plasticity Enhances the Brain Penetration of a Metabolically Stable, Dual-Functional Opioid-Peptide CycloAnt. [PDF]

Int J Mol Sci
Li Y, Cotham WE, Eliasof A, Bland K, Walla M, Pellechia PJ, Chen C, Fan D, McLaughlin JP, Liu-Chen LY.   +9 more
europepmc   +1 more source

Progress of arylacetamide deacetylase research in metabolic diseases. [PDF]

Front Oncol
Yang L, Liao ZZ, Ran L, Xiao XH.
europepmc   +1 more source

New structural scaffolds to enhance the metabolic stability of arginine-derived PAD4 inhibitors. [PDF]

Results Chem
Jia Y, Bahraminejad S, Jiang C, Taledaohan A, Ma D, Jiang J, Wang Y, Liu J.   +7 more
europepmc   +1 more source

In vitro hydrolysis of areca nut xenobiotics in human liver. [PDF]

Drug Metab Pharmacokinet
Paolillo V, Jayakumar M, Sheperd C, Tran A, Hoang S, Dao N, Jain P, Myers AL.   +7 more
europepmc   +1 more source

In vitro safety evaluation of dopamine D3R antagonist, R-VK4-116, as a potential medication for the treatment of opioid use disorder. [PDF]

PLoS One
Nandre RM, Newman AH, Terse PS.
europepmc   +1 more source

Application of Deuterium in an M₁ Positive Allosteric Modulator Back-Up Program: The Discovery of VU6045422. [PDF]

ACS Chem Neurosci
Engers JL, Li J, Han C, Long MF, Gregro AR, Presley CC, Dickerson JW, Peng W, Cho HP, Rodriguez AL, Xiang Z, Boutaud O, O'Carroll C, Dey PM, Burstein ES, Niswender CM, Rook JM, Conn PJ, Engers DW, Lindsley CW.   +19 more
europepmc   +1 more source

Hepatoprotective Effects of Resveratrol on Acetaminophen-Induced Acute Liver Injury and Its Implications for Tofacitinib Disposition in Rats. [PDF]

Biomol Ther (Seoul)
Choi HG, Park SY, Bae SH, Chang SY, Kim SH.   +4 more
europepmc   +1 more source

The preclinical pharmacokinetics of Tolinapant-A dual cIAP1/XIAP antagonist with in vivo efficacy. [PDF]

Pharmacol Res Perspect
Martins V, Ward G, Smyth T, Reader M, Chessari G, Johnson C, Wilsher N.   +6 more
europepmc   +1 more source

Sex differences in CYP450-based sodium dehydroacetate metabolism and its metabolites in rats. [PDF]

NPJ Sci Food
Zhang M, Du P, Xiao Y, Liu H, Wang M, Zhang Y, Chen X.   +6 more
europepmc   +1 more source

Human and rat renal proximal tubule in vitro models for ADME applications. [PDF]

Arch Toxicol
Klatt OC, de Brouwer L, Hendriks F, Dehne EM, Ataç Wagegg B, Jennings P, Wilmes A.   +6 more
europepmc   +1 more source