Results 171 to 180 of about 97,218 (302)

CHANGES IN THE COMPOSITION OF RABBIT LIVER AND OF LIVER MICROSOME FRACTIONS FOLLOWING BIRTH [PDF]

, 1964
G. H. Lathe, T.R. Ricketts
openalex   +1 more source

Evidence for vitellogenin DNA‐binding in honey bees

Protein Science, Volume 34, Issue 10, October 2025.
Abstract DNA‐binding proteins play essential roles in DNA replication, DNA repair, DNA organization, and several aspects of gene regulation. Their well‐studied structures and charge configurations aid in identifying similar functions in other proteins. Vitellogenin (Vg) is a highly conserved protein that is central to egg‐yolk formation in most animal ...
Gyan Harwood, Vilde Leipart, Chris Elsik, Joseph C. F. Ng, Finn Drabløs, Gro V. Amdam   +5 more
wiley   +1 more source

7α-Hydroxylation of cholestanol by rat liver microsomes

, 1968
Sarah Shefer, Susan Hauser, Erwin H. Mosbach   +2 more
openalex   +1 more source

The incorporation of cytidine 5′-monophosphate and other ribonucleotides by an enzyme preparation from rat-liver microsomes [PDF]

, 1967
MG Page, GR Haynes, H.G. Klemperer
openalex   +1 more source

The serine palmitoyl transferase of plant pathogenic fungi: a promising new target for the development of novel crop protection solutions†

Pest Management Science, Volume 81, Issue 10, Page 6567-6578, October 2025.
High biological activity of pyridazine carboxamides against a wide range of Ascomycetes led to identification of a new biochemical target for agrochemical fungicides – serine palmitoyl transferase. Abstract BACKGROUND Plant pathogens pose a significant threat to global agriculture and, thus to world food supplies, requiring the development of ...
Lionel Nicolas, Emilia Hilz, Stephanie Gamet, Vincent Thomas, Stephane Peyrard, Luigi Di Vietro, Benedicte Cirer, Julie Geist, Bernd Essigmann, Anne Ferry, Angeline Chanel, Frédéric Berniaud, Dominik Schwarz, Virginie Lempereur   +13 more
wiley   +1 more source

Characterization of trazodone metabolic pathways and species-specific profiles. [PDF]

Front Pharmacol
Petrucci V, Dragone P, Laurenti MC, Oggianu L, Zabela V, Cattaneo A.   +5 more
europepmc   +1 more source

A Second Ouabain-sensitive Sodium-dependent Adenosine Triphosphatase in Brain Microsomes

, 1969
Arthur H. Neufeld, Harvey M. Levy
openalex   +1 more source

Predicting Systemic and Liver Bosentan Exposure Using Physiologically‐Based Pharmacokinetic Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 10, Page 1715-1726, October 2025.
ABSTRACT Bosentan is the first approved oral medication for pulmonary arterial hypertension, yet the black‐box warning on its labeling implies a substantial risk of liver injury associated with bosentan exposure. The risk assessment of bosentan‐induced liver injury requires a thorough understanding of the underlying mechanisms, for which there is ...
Miao‐Chan Huang, Julia Macente, Sofie Heylen, Chen Ning, Kristof De Vos, Neel Deferm, Pieter Annaert   +6 more
wiley   +1 more source

PBPK Modeling to Predict Clinical Drug–Drug Interaction and Impact of Hepatic Impairment for an ADC With the Payload Auristatin F‐Hydroxypropylamide

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 10, Page 1661-1672, October 2025.
ABSTRACT Upifitamab rilsodotin—an antibody drug conjugate (ADC)—comprises a NaPi2b‐targeted antibody conjugated to an auristatin‐based payload (auristatin F‐hydroxypropylamide [AF‐HPA]). AF‐HPA is metabolized by cytochrome P450 3A4 (CYP3A4) and, to a lower extent, by CYP3A5 and demonstrates both reversible and time‐dependent inhibition of CYP3A4.
Niyanta Kumar, Vaishali Dixit, Howard Burt, Katherine L. Gill, Hannah M. Jones, Natalie Keirstead, Dian Su, Dorin Toader, Timothy B. Lowinger   +8 more
wiley   +1 more source

A Rapid and Sensitive Method for the Measurement of Biological Oxidation of an Aromatic Hydrocarbon Catalyzed by Liver Microsomes. [PDF]

, 1967
Robert Nilsson, Gunnar Ahnström, Tore Ledaal, Pär Holmberg, G. Eriksson, R. Blinc, S. Paušak, L. Ehrenberg, J. Dumanović   +8 more
openalex   +1 more source