Results 221 to 230 of about 129,619 (377)

Development of a near-infrared fluorescent probe for the selective detection of severe hypoxia. [PDF]

open access: yesRSC Chem Biol
Kasai T   +6 more
europepmc   +1 more source

Preclinical Pharmacokinetic Assessment of a Promising Vasorelaxant, Analgesic, and Anti‐Inflammatory Prototype 5‐[1‐(4‐Fluorophenyl)‐1H‐pyrazol‐4‐yl]‐2H‐tetrazole (LQFM020) Through Selective Bioanalytical HPLC‐PDA‐Based Method

open access: yesBiomedical Chromatography, Volume 39, Issue 5, May 2025.
ABSTRACT A simple and selective high‐performance liquid chromatography bioanalytical method was developed and validated to determine the pharmacokinetic parameters of 5‐[1‐(4‐fluorophenyl)‐1H‐pyrazol‐4‐yl]‐2H‐tetrazole (LQFM020) with promising vasorelaxant, anti‐inflammatory, and antinociceptive properties while verifying its potential hepatic enzyme ...
Lanussy Porfiro de Oliveira   +10 more
wiley   +1 more source

Activatable Photosensitizers: From Fundamental Principles to Advanced Designs

open access: yesAngewandte Chemie, Volume 137, Issue 15, April 7, 2025.
Basic concepts of designing activatable photosensitizers are established in this Review by closely examining quenching mechanisms and bioresponsive constructs essential for their function. New strategies developed in the last five years that address the shortcomings of conventional activatable photosensitizers and which enhance selectivity are also ...
Nahyun Kwon   +3 more
wiley   +2 more sources

Species Differences in Ezetimibe Glucuronidation. [PDF]

open access: yesMetabolites
Emmanuel S   +5 more
europepmc   +1 more source

Some Physicochemical Properties of Ribonucleoprotein from Rat Liver Microsomes

open access: hybrid, 1962
Mary G. Hamilton   +2 more
openalex   +1 more source

Purification of prostaglandin endoperoxide synthetase from bovine vesicular gland microsomes.

open access: yesJournal of Biological Chemistry, 1976
T. Miyamoto   +3 more
semanticscholar   +1 more source

Transgenerational Reproductive and Developmental Toxicity Induced by N‐Nitrosodimethylamine and Its Metabolite Formaldehyde in Drosophila melanogaster

open access: yesJournal of Applied Toxicology, Volume 45, Issue 5, Page 841-857, May 2025.
ABSTRACT N‐Nitrosodimethylamine (NDMA) is a known water disinfection byproduct (DBP) characterized as a potent hepatotoxin, promutagen, and probable human carcinogen; this is because of the metabolites associated with its biotransformation. The metabolism of NDMA produces formaldehyde, another alkylating agent and DBP. Both compounds are generated from
Oscar Eduardo Tabares‐Mosquera   +3 more
wiley   +1 more source

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