Results 41 to 50 of about 49,535,711 (155)
KIF14 and citron kinase act together to promote efficient cytokinesis [PDF]
, 2006 Multiple mitotic kinesins and microtubule-associated proteins (MAPs) act in concert to direct cytokinesis (Glotzer, M. 2005. Science. 307:1735-1739). In anaphase cells, many of these proteins associate with an antiparallel array of microtubules termed ...
Erich A. Nigg +27 more
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Chemical Synthesis of Microtubule-Associated Protein Tau 2N4R [PDF]
, 2023 Deposits of the microtubule-associated protein tau (MAPT) serve as a hallmark of neurodegenerative diseases known as tauopathies. Numerous studies have demonstrated that in diseases such as Alzheimer’s disease (AD), tau undergoes extensive remodeling ...
Maciej, Walczak +2 more
core +2 more sources
Frontiers in Physiology, 2017 Chronic stress induces endocrine disturbance, which contributes to the development of polycystic ovary syndrome (PCOS), a condition that remains a challenge for clinicians to cope with.
Hao-Yu Sun +28 more
doaj +1 more source
Physiological Reports, 2021 Mechanistic target of rapamycin complex 1 (mTORC1) plays a central role in muscle protein synthesis and repeated bouts of resistance exercise (RE) blunt mTORC1 activation.
Takaya Kotani +5 more
doaj +1 more source
A study of M0R1/GEM1 and kinl-like kinesins arabidopsis [PDF]
, 2004 Microtubules perform essential functions in eukaryotic cells and, with other cytoskeletal elements, are involved in diverse cellular processes. Plant cells construct four microtubule arrays; There are two cortical arrays, the interphase cortical array ...
Hawkins, Timothy James
core
Change in tau phosphorylation associated with neurodegeneration in the ME7 model of prion disease
, 2010 Hyperphosphorylation of the microtubule-associated protein tau is a significant determinant in AD (Alzheimer's disease), where it is associated with disrupted axonal transport and probably causes synaptic dysfunction.
Perry, V. Hugh +2 more
core +1 more source
Agrin promotes acetylcholine receptor clustering at the mammalian neuro-muscular junction by PI3K/GSK3ß²-mediated regulation of +TIPs and microtubule capture [PDF]
, 2013 Neurotransmission an der neuromuskulären Endplatte von Säugetieren erfolgt durch Ausschüttung von Acetylcholin (ACh) aus motorischen Nerven in den synaptischen Spalt und verursacht letztendlich Muskelkontraktion im angesteuerten Muskel.
Sladecek, Stefan
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CosmeticsFocusing on the anti-aging mechanism and efficient utilization of anti-aging active ingredients in the skin is an excellent strategy to mitigate aging. In this study, ribose/collagen/decarboxylated carnitine hydrochloride/palmitoyl tripeptide-1 composite
Min Liu +6 more
doaj +1 more source
Neural Regeneration Research, 2015 MicroRNA-9 (miR-9) has been shown to promote the differentiation of bone marrow mesenchymal stem cells into neuronal cells, but the precise mechanism is unclear.
Guang-yu Zhang +5 more
doaj +1 more source
DAP1 regulates osteoblast autophagy via the ATG16L1–LC3 axis in Graves’ disease-induced osteoporosis
Journal of Orthopaedic Surgery and Research, 2023 Objective This study aimed to uncover a critical protein and its mechanisms in modulating autophagy in Graves’ disease (GD)-induced osteoporosis (OP).
Mingdong Gao +4 more
doaj +1 more source