Results 31 to 40 of about 49,535,711 (155)

Distinct Lysosomal Network Protein Profiles in Parkinsonian Syndrome Cerebrospinal Fluid

open access: yesJournal of Parkinson’s Disease, 2016
Background: Clinical diagnosis of parkinsonian syndromes like Parkinson’s disease (PD), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP) is hampered by overlapping symptomatology and lack of diagnostic biomarkers, and definitive ...
Andrea Boman   +8 more
doaj   +1 more source

A molecular analysis of the microtubule associated protein MAP65-1 [PDF]

open access: yes, 2006
Microtubules (MTs) play important roles in various cellular processes including cell division, organelle movement and the determination of cellular morphology. The dynamics and organization of microtubules are regulated by microtubule associated proteins
Hsin Yu, Chang
core  

Electroacupuncture pretreatment alleviated cerebral ischemia-reperfusion injury via suppressing autophagy in cerebral cortex tissue in rats

open access: yes针刺研究, 2019
ObjectiveTo investigate the effect of electroacupuncture(EA)preconditioning on autophagy in cerebral cortex tissues of rats with cerebral ischemia-reperfusion injury(CIRI),so as to explore its mechanisms underlying improvement of CIRI.MethodsThirty-three
HUANG Ya-guang   +5 more
doaj   +2 more sources

SNHG12 Promotes Autophagy by Blocking the mTOR-Primary Cilia-mTOR Loop via Activating the miR-181a-5p/miR-138-5p-INPP5E Axis in Chondrocyte

open access: yesInternational Journal of Clinical Practice
Diseases related to cartilage abnormalities pose a serious threat to human health. Normal cartilage contains only one type of cell, chondrocytes. This study aims to investigate the impact of inositol polyphosphate-5-phosphatase E (INPP5E) on chondrocytes
Weijia Feng   +4 more
doaj   +1 more source

Does Exercise Regulate Autophagy in Humans? A Systematic Review and Meta-Analysis

open access: yesAutophagy Reports, 2023
Background Macroautophagy/autophagy is an essential recycling process that is involved in a wide range of biological functions as well as in diseases. The regulation of autophagy by exercise and the associated health benefits have been revealed by rodent
Xiang-Ke Chen   +5 more
doaj   +1 more source

A study of the Microtubule associated protein family, MAP65, in Arabidopsis [PDF]

open access: yes, 2004
Microtubules (MTs) play a key role in cell division and morphogenesis. Plant cells form four distinct MT arrays through the cell cycle; the interphase cortical array, the preprophase band, the spindle and the phragmoplast.
Kaloriti, Despina
core  

The possible effect of coenzyme Q10 and captopril on acetaminophen-induced encephalopathy in rats: possible influence on autophagy, antioxidant and Na + /K + ATPase

open access: yesArchives of Medical Science, 2020
Introduction Induction of autophagy could protect against acetaminophen (APAP)-induced hepatotoxicity; however, little is known about the role of autophagy in APAP-induced encephalopathy (APAP-E). This study aimed to evaluate the effects of coenzyme Q10 (
Heba M. Galal   +2 more
doaj   +1 more source

BNIP3 phosphorylation by JNK1/2 promotes mitophagy via enhancing its stability under hypoxia

open access: yesCell Death and Disease, 2022
Mitophagy is an important metabolic mechanism that modulates mitochondrial quality and quantity by selectively removing damaged or unwanted mitochondria.
Yun-Ling He   +11 more
doaj   +1 more source

The identification of the Tao-1 kinase as a key regulator of microtubule dynamics [PDF]

open access: yes, 2009
In a multicellular animal, the different functions of cells are dependent on their diversity of shapes. Protein phosphorylation and dephosphorylation play an important role in altering the cell shape in response to internal and external signals. In this
Liu, T, Liu, T.
core  

Effect of Sirolimus on the Level of Peripheral Blood Lymphocyte Autophagy in Children With Systemic Lupus Erythematosus

open access: yesFrontiers in Pediatrics, 2021
Background: To observe the changes of autophagy-related protein levels in peripheral blood lymphocytes before and after sirolimus treatment in children with systemic lupus erythematosus (SLE).Methods: Children with SLE were randomly divided into two ...
Xinliang Wang   +7 more
doaj   +1 more source

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