The study reports a DNA/RNA heteroduplex hydrogel (SeroPTEN‐CG) that undergoes DNase‐mediated hydrogel‐to‐nanogel transition for spinal cord injury therapy by targeting the serotonergic system, combining 5‐hydroxytryptamine (5‐HT)‐mediated excitability restoration to reactivate dormant interneurons with phosphatase and tensin homolog (PTEN)‐targeted ...
Chunlin Li +19 more
wiley +1 more source
Not another round: microtubule-associated proteins and the control of fruit shape in tomato. [PDF]
Herrera-Ubaldo H.
europepmc +1 more source
PiT2 regulates neuronal outgrowth through interaction with microtubule-associated protein 1B [PDF]
Xixiang Ma +19 more
openalex +1 more source
Hybrid piezoelectric scaffolds offer a promising route for Central Nervous System regeneration by combining structural and electrical cues to support neural stem cell growth. This review highlights their potential to overcome current challenges in neural tissue engineering by exploring porous hybrid materials, their biological interactions, and ...
Heather F. Titterton +2 more
wiley +1 more source
Myomegalin is necessary for the formation of centrosomal and Golgi-derived microtubules
Summary The generation of cellular microtubules is initiated at specific sites such as the centrosome and the Golgi apparatus that contain nucleation complexes rich in γ-tubulin.
Régine Roubin +6 more
doaj +1 more source
Modulus‐Switchable Miniature Robots for Biomedical Applications: A Review
Materials, robot designs, proof‐of‐concept functions, and biomedical applications of modulus‐switchable miniature robots. Miniature soft robots have shown great potential in biomedical applications due to their excellent controllability and suitable mechanical properties in biological environments.
Chunyun Wei, Yibin Wang, Jiangfan Yu
wiley +1 more source
New insights into the functions and regulations of MAP215/MOR1 and katanin, two conserved microtubule-associated proteins in Arabidopsis. [PDF]
Liu X, Yu F.
europepmc +1 more source
Functionally specific binding regions of microtubule-associated protein 2c exhibit distinct conformations and dynamics [PDF]
Kateřina Melková +10 more
openalex +1 more source
YAP undergoes phase separation to activate the AJUBA super‐enhancer, driving aberrant mitosis through spindle checkpoint dysregulation in breast cancer. This study uncovers a mechanistic link between YAP condensates, super‐enhancer activation, and aneuploidy formation.
Rui Zhang +8 more
wiley +1 more source
Microtubule-associated proteins WDL5 and WDL6 play a critical role in pollen tube growth in <i>Arabidopsis thaliana</i>. [PDF]
Okamoto T, Motose H, Takahashi T.
europepmc +1 more source

