Results 41 to 50 of about 397,871 (335)

Modes of flagellar assembly in Chlamydomonas reinhardtii and Trypanosoma brucei

eLife, 2014
Defects in flagella growth are related to a number of human diseases. Central to flagellar growth is the organization of microtubules that polymerize from basal bodies to form the axoneme, which consists of hundreds of proteins.
Johanna L Höög, Sylvain Lacomble, Eileen T O’Toole, Andreas Hoenger, J Richard McIntosh, Keith Gull   +5 more
doaj   +1 more source

Dictyostelium Cell Fixation: Two Simple Tricks

Methods and Protocols, 2020
We share two simple modifications to enhance the fixation and imaging of relatively small, motile, and rounded model cells. These include cell centrifugation and the addition of trace amounts of glutaraldehyde to existing fixation methods.
Michael Koonce, Irina Tikhonenko, Ralph Gräf   +2 more
doaj   +1 more source

The life of a microtubule

Molecular Biology of the Cell, 2018
The Minisymposium “The Life of a Microtubule: Birth, Dynamics and Function†highlighted new findings on how microtubules (MTs) are made, how their length and spatial organization is regulated, and finally how they contribute to cellular functions.
Dixit, Ram, Petry, Sabine
openaire   +4 more sources

Structural plasticity of the living kinetochore [PDF]

, 2017
The kinetochore is a large, evolutionarily conserved protein structure that connects chromosomes with microtubules. During chromosome segregation, outer kinetochore components track depolymerizing ends of microtubules to facilitate the separation of ...
Akiyoshi, Al-Bassam, Aravamudhan, Aravamudhan, Asbury, Biggins, Biggins, Boris Rubinstein, Brian D. Slaughter, Chan, Cheeseman, Culotti, Daniel, De Wulf, Desai, Duffy, Field, Foley, Gandhi, Gao, Gardner, Gestaut, Grishchuk, Guimaraes, Hartwell, He, Hedges, Hill, Hornung, Hornung, Jaspersen, Jay R. Unruh, Jeffrey J. Lange, Jennifer L. Gerton, Jin, Jin, Joglekar, Joglekar, Joglekar, Joglekar, Karthik Dhatchinamoorthy, Kim, Kosco, Lampert, Liu, Longtine, Mallavarapu, Malvezzi, Manjunatha Shivaraju, Mayer, McAinsh, McIntosh, McKinney, Meng, Mieck, Miller, Miranda, Ng, Obuse, Pavelka, Pearson, Pfau, Podolski, Powers, Ramey, Sarangapani, Schleiffer, Schmidt, Severin, Shivaraju, Smith, Stephens, Su, Suzuki, Tanaka, Tien, Tytell, Umbreit, Usui, van Breugel, van Hooff, Visintin, Walczak, Wang, Welburn, Westermann, Westermann, Winey, Wisniewski, Wolyniak, Yuen   +90 more
core   +1 more source

Fractal, Scale Free Electromagnetic Resonance of a Single Brain Extracted Microtubule Nanowire, a Single Tubulin Protein and a Single Neuron

Fractal and Fractional, 2020
Biomaterials are primarily insulators. For nearly a century, electromagnetic resonance and antenna–receiver properties have been measured and extensively theoretically modeled.
Komal Saxena, Pushpendra Singh, Pathik Sahoo, Satyajit Sahu, Subrata Ghosh, Kanad Ray, Daisuke Fujita, Anirban Bandyopadhyay   +7 more
doaj   +1 more source

The Dam1 ring binds to the E-hook of tubulin and diffuses along the microtubule. [PDF]

, 2011
There has been much effort in recent years aimed at understanding the molecular mechanism by which the Dam1 kinetochore complex is able to couple microtubule depolymerization to poleward movement. Both a biased diffusion and a forced walk model have been
Barnes, Georjana, Drubin, David, Liu, Jian, Nakajima, Yuko, Nogales, Eva, Ramey, Vincent H, Wang, Hong-Wei, Wong, Amanda   +7 more
core   +2 more sources

Peripheral nerve repair: a hot spot analysis on treatment methods from 2010 to 2014

Neural Regeneration Research, 2015
Therapeutic strategies for neurological deficits and for promoting nerve regeneration after peripheral nerve injuries have received much focus in clinical research.
Guang-yao Liu, Yan Jin, Qiao Zhang, Rui Li   +3 more
doaj   +1 more source

Microtubules born on microtubules

The Journal of Cell Biology, 2005
![Graphic][1] A new MT is nucleated (white arrowhead) by a γ-TuC (green) that sits on an existing MT bundle.Microtubule (MT) arrays form, say Janson et al. ( [page 297][2]), when MT nucleators stick to existing MTs.
openaire   +3 more sources

Measuring and modeling polymer gradients argues that spindle microtubules regulate their own nucleation

, 2017
Spindles are self-organized microtubule-based structures that segregate chromosomes during cell division. The mass of the spindle is controlled by the balance between microtubule turnover and nucleation. The mechanisms that control the spatial regulation
Foster, Peter J., Fürthauer, Sebastian, Kaye, Bryan, Needleman, Daniel J., Shelley, Michael J., Stiehl, Olivia   +5 more
core   +1 more source

Mitotic spindle scaling during Xenopus development by kif2a and importin α

eLife, 2013
Early development of many animals is characterized by rapid cleavages that dramatically decrease cell size, but how the mitotic spindle adapts to changing cell dimensions is not understood.
Jeremy D Wilbur, Rebecca Heald
doaj   +1 more source