Kinetochore-microtubule error correction is driven by differentially regulated interaction modes [PDF]
, 2015 For proper chromosome segregation, sister kinetochores must interact with microtubules from opposite spindle poles (bi-orientation). To establish bi-orientation, aberrant kinetochore-microtubule attachments are disrupted (error correction) by aurora B ...
Kalantzaki, Maria +5 more
core +1 more source
The kinesin-12 Kif15 is a processive track-switching tetramer [PDF]
, 2014 Kinesin-12 motors are a little studied branch of the kinesin superfamily with the human protein (Kif15) implicated in spindle mechanics and chromosome movement.
McHugh, Toni +9 more
core +1 more source
A Microtubule-Associated Protein Is Essential for Malaria Parasite Transmission
mBio, 2023 Mature gametocytes of Plasmodium falciparum display a banana (falciform) shape conferred by a complex array of subpellicular microtubules (SPMT) associated with the inner membrane complex (IMC).
Jan Stephan Wichers-Misterek +10 more
doaj +1 more source
Flow-induced buckling of elastic microfilaments with non-uniform bending stiffness
Frontiers in Soft Matter, 2023 Buckling plays a critical role in the transport and dynamics of elastic microfilaments in Stokesian fluids. However, previous work has only considered filaments with homogeneous structural properties.
Thomas Nguyen, Harishankar Manikantan
doaj +1 more source
A "MICROTUBULE" IN A BACTERIUM [PDF]
The Journal of Cell Biology, 1967 A study of the anchorage of the flagella in swarmers of Proteus mirabilis led to the incidental observation of microtubules. These microtubules were found in thin sections and in whole mount preparations of cells from which most of the content had been released by osmotic shock before staining negatively with potassium phosphotungstate (PTA).
W, van Iterson +2 more
openaire +2 more sources
Microtubule-Associated Protein EB3 Regulates IP3 Receptor Clustering and Ca(2+) Signaling in Endothelial Cells. [PDF]
, 2015 The mechanisms by which the microtubule cytoskeleton regulates the permeability of endothelial barrier are not well understood. Here, we demonstrate that microtubule-associated end-binding protein 3 (EB3), a core component of the microtubule plus-end ...
F. Huang (2379355) +6 more
core +4 more sources
Structural model for differential cap maturation at growing microtubule ends
eLife, 2020 Microtubules (MTs) are hollow cylinders made of tubulin, a GTPase responsible for essential functions during cell growth and division, and thus, key target for anti-tumor drugs. In MTs, GTP hydrolysis triggers structural changes in the lattice, which are
Juan Estévez-Gallego +16 more
doaj +1 more source
Tubulin Polymerization Promoting Protein Affects the Circadian Timing System in C57Bl/6 Mice
Journal of Circadian Rhythms, 2021 The circadian timing system (CTS) is a complex set of cyclic cellular mechanisms which serve to synchronize discrete cell groups across multiple organ systems to adapt the body’s physiology to a (roughly) 24-hour clock.
Eric Barbato +2 more
doaj +1 more source
Sds22 regulates aurora B activity and microtubule-kinetochore interactions at mitosis [PDF]
, 2010 We have studied Sds22, a conserved regulator of protein phosphatase 1 (PP1) activity, and determined its role in modulating the activity of aurora B kinase and kinetochore-microtubule inter-actions.
DeLuca, Jennifer G. +11 more
core +1 more source
Light microscopical study of endosperm formation in Brassica napus L.
Acta Societatis Botanicorum Poloniae, 2014 The cellularization of the endosperm of Brassica napus was investigated with light microscopy after embedment in Technovit 7100. The microtubular cytoskeleton was visualized by immunofluorescence techniques after embedment in butyl methyl metacrylate ...
A. A.M. van Lammeren +3 more
doaj +1 more source