Results 41 to 50 of about 289,777 (310)

Self-straining of actively crosslinked microtubule networks [PDF]

, 2019
Cytoskeletal networks are foundational examples of active matter and central to self-organized structures in the cell. In vivo, these networks are active and densely crosslinked. Relating their large-scale dynamics to the properties of their constituents
Lemma, Bezia, Shelley, Michael J, Needleman, Daniel J, Zvonimir Dogic, Michael J. Shelley, Peter J. Foster, Bezia Lemma, Claire E. Walczak, Ems-McClung, Stephanie C, Foster, Peter, Dogic, Zvonimir, Walczak, Claire E, Yu, Che-Hang, Fürthauer, Sebastian, Foster, Peter J, Ems-McClung, Stephanie, Sebastian Fürthauer, Che-Hang Yu, Walczak, Claire, Stephanie C. Ems-McClung, Needleman, Daniel, Daniel J. Needleman, Shelley, Michael   +22 more
core   +1 more source

The adenomatous polyposis coli protein unambiguously localizes to microtubule plus-ends and is involved in establishing parallel arrays of microtubule bundles in highly polarised epithelial cells [PDF]

, 2002
Loss of full-length adenomatous polyposis coli (APC) protein correlates with the development of colon cancers in familial and sporadic cases. In addition to its role in regulating ß-catenin levels in the Wnt signaling pathway, the APC protein is ...
John B. Mackie, Mackie, JB, Nathke, Inke S.; id_orcid, Prescott, AR, Nathke, IS, Mogensen, MM, Mette M. Mogensen, Prescott, Alan R.; id_orcid, Mackie, John B., Tucker, John B., Inke S. Näthke, Näthke, Inke S., John B. Tucker, Mogensen, Mette M., Prescott, Alan R., Alan R. Prescott, Tucker, John Barry   +16 more
core   +1 more source

Intrinsic and Extrinsic Factors Affecting Microtubule Dynamics in Normal and Cancer Cells

Molecules, 2020
Microtubules (MTs), highly dynamic structures composed of α- and β-tubulin heterodimers, are involved in cell movement and intracellular traffic and are essential for cell division.
Filip Borys, Ewa Joachimiak, Hanna Krawczyk, Hanna Fabczak   +3 more
doaj   +1 more source

Prime movers : mechanochemistry of mitotic kinesins [PDF]

, 2014
Mitotic spindles are self-organizing protein machines that harness teams of multiple force generators to drive chromosome segregation. Kinesins are key members of these force-generating teams.
Cross, R. A., McAinsh, Andrew D.
core   +1 more source

Cooperation of Various Cytoskeletal Components Orchestrates Intercellular Spread of Mitochondria between B-Lymphoma Cells through Tunnelling Nanotubes

Cells
Membrane nanotubes (NTs) are dynamic communication channels connecting spatially separated cells even over long distances and promoting the transport of different cellular cargos.
Henriett Halász, Viktória Tárnai, János Matkó, Miklós Nyitrai, Edina Szabó-Meleg   +4 more
doaj   +1 more source

The Tubulin Code in Mitosis and Cancer

Cells, 2020
The “tubulin code” combines different α/β-tubulin isotypes with several post-translational modifications (PTMs) to generate microtubule diversity in cells.
Danilo Lopes, Helder Maiato
doaj   +1 more source

Cell proliferation, cell shape, and microtubule and cellulose microfibril organization of tobacco BY-2 cells are not altered by exposure to near weightlessness in space [PDF]

, 2009
The microtubule cytoskeleton and the cell wall both play key roles in plant cell growth and division, determining the plant’s final stature. At near weightlessness, tubulin polymerizes into microtubules in vitro, but these microtubules do not self ...
Emons, A.M.C., Jan W. Vos, Emons, A.M.C. (Anne Mie), Anne Mie C. Emons, Kieft, H., Sieberer, B., Vos, J.W., Franssen-Verheijen, M.A.W., Tiny Franssen-Verheijen, Björn J. Sieberer, Vos, J.W. (Jan), Sieberer, B.J., Henk Kieft, Franssen-Verheijen, T.   +13 more
core   +1 more source

MAP2 phosphorylation: mechanisms, functional consequences, and emerging insights

Frontiers in Cellular Neuroscience
Microtubule-associated protein 2 (MAP2) is a key regulator of cytoskeletal dynamics and neuronal function. It stabilizes microtubules, shapes dendrites, influences synaptic plasticity, and regulates transportation and protein synthesis through its ...
Jiali Lyu, Jiali Lyu, Andrew G. DeMarco, Robert A. Sweet, Robert A. Sweet, Robert A. Sweet, Melanie J. Grubisha, Melanie J. Grubisha   +7 more
doaj   +1 more source

S. pombe kinesins-8 promote both nucleation and catastrophe of microtubules [PDF]

, 2012
The kinesins-8 were originally thought to be microtubule depolymerases, but are now emerging as more versatile catalysts of microtubule dynamics. We show here that S.
Muriel Erent (185011), Douglas R Drummond, Cross, R. A., Douglas R. Drummond (185016), Erent, Muriel, Cross Robert A., Drummond, Douglas R., Drummond Douglas R., Muriel Erent, Robert A. Cross (185019), Robert A Cross, Erent Muriel   +11 more
core   +1 more source

The polar code for patterning: how polarity and the cytoskeleton orchestrate asymmetric cell division during plant development

Frontiers in Cell and Developmental Biology
Cell polarity is fundamental to morphogenesis across living organisms. In plants, a dynamic interplay between polarity cues and the cytoskeleton orchestrates essential asymmetric cell divisions across diverse species.
Akanksha Garhewal, Gabriel J. Angres, Andrew Muroyama   +2 more
doaj   +1 more source