Results 161 to 170 of about 21,311 (203)

Acetylated microtubules are essential for touch sensation in mice

, 2016
The sense of touch depends upon the transformation of mechanical energy into electrical signals by peripheral sensory neurons and associated cells in the skin. This conversion is thought to be mediated by a complex of proteins in which ion channels such as Piezo2 function as mechanotransducers.
openaire   +1 more source

Tubulin Post-Translational Modifications in Cardiovascular Diseases: Emerging Mechanisms and Therapeutic Modulation by Traditional Chinese Medicine

Drug Design, Development and Therapy
Yangfan Qi,1 Yiyi Zhou,2 Xinyue Ning,1 Jiahao Ye,1,3 Zhixi Hu,1,3 Lin Li1,3 1School of Traditional Chinese Medicine, Hunan University of Chinese Medicine, Changsha, Hunan, People’s Republic of China; 2Medical School, Hunan University of Chinese Medicine,
Qi Y, Zhou Y, Ning X, Ye J, Hu Z, Li L
doaj  

Pharmacologically increasing microtubule acetylation corrects stress-exacerbated effects of organophosphates on neurons. [PDF]

Traffic, 2017
Rao AN, Patil A, Brodnik ZD, Brodnik ZD, Qiang L, España RA, Sullivan KA, Black MM, Baas PW.   +8 more
europepmc   +1 more source

Modulation Of Microtubule Acetylation By The Interplay Of TPPP/p25, SIRT2 And New Anticancer Agents With Anti-SIRT2 Potency. [PDF]

Sci Rep, 2017
Szabó A, Oláh J, Szunyogh S, Lehotzky A, Szénási T, Csaplár M, Schiedel M, Lőw P, Jung M, Ovádi J.   +9 more
europepmc   +1 more source

Prognostic, diagnostic and therapeutic value of the cancer tubulin code. [PDF]

Cancer Metastasis Rev
Vilela C, Gomes-Andrade D, Silva S, Maiato H.   +3 more
europepmc   +1 more source

Post-translational modifications as a regulatory code for tau function in health and disease. [PDF]

Front Dement
Nordbeck AJ, Sharma B, Garcia CA, Tseng JH.   +3 more
europepmc   +1 more source

Microtubule dynamics and post-translational modifications in cardiovascular diseases: mechanisms and therapeutic implications. [PDF]

Front Cardiovasc Med
Cui L, Guo L, Yang L, Zhang Y, Ma C.
europepmc   +1 more source

Multiple Regulatory Mechanisms of Post-Translational Modifications and Therapeutic Potential of Mitotic Catastrophe. [PDF]

Int J Mol Sci
Zhang QY, Chen X, Li SK, Cao LZ, Wang SY, He YJ, Zhang XL, Liu JW, Liu XF.   +8 more
europepmc   +1 more source

Biophysical assessment of the molecular mechanisms of Tau aggregation and its role in Alzheimer's disease. [PDF]

Protein Sci
Skrehot JT, Kurouski D.
europepmc   +1 more source

PM_2.5-Induced Multinucleation of Bronchial Epithelial Cells due to Microtubule Overacetylation and Disruption of Microtubule-Associated Proteins. [PDF]

Environ Health (Wash)
Xiao L, Pang J, Guo Z, Zhang K, Xiong Z, Yang M, Wang J, Li Y, Lynch I.   +8 more
europepmc   +1 more source