Results 151 to 160 of about 204,218 (228)

Acetylation‐Deacetylation‐Driven Natural Product Biosynthesis

open access: yesChemistryEurope, EarlyView.
This review summarizes the role of acetylation‐deacetylation in natural product biosynthesis, including acetylation followed by deacetylation after several biosynthetic steps, acetylation‐mediated rearrangement, acetylation‐triggered elimination, and the acetylation cycle as a regulatory mechanism. These processes are vital for the formation of complex
Huibin Wang, Ikuro Abe
wiley   +1 more source

The impact of Connexin 43 deficiency on the cell shape and cytoskeleton of murine Sertoli cells: A house with ramshackle walls? [PDF]

open access: yesPLoS One
Ueffing M   +11 more
europepmc   +1 more source

Total Synthesis of (+)‐Disorazole Z1

open access: yesChemistry – A European Journal, EarlyView.
The first total synthesis of disorazole Z1, a highly up to picomolar active cytotoxic natural product, is presented. An acyclic carbon chain containing a chiral quaternary carbon center surrounded by two chiral secondary alcohols was synthesized and combined with a functionalized diene‐stannane to obtain the carbon skeleton of one half of disorazole Z1.
Thomas J. Bauer   +3 more
wiley   +1 more source

"Shape of Cell"-An Auxin and Cell Wall Duet. [PDF]

open access: yesPhysiol Plant
Kumar V, Yadav S, Heymans A, Robert S.
europepmc   +1 more source

The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation

open access: yesCytoskeleton, EarlyView.
ABSTRACT Mutations in CCDC11 (cfap53) have been identified in multiple patients with heterotaxy (Htx), a disorder of left–right (LR) patterning of the internal organs. In Xenopus, depletion of Ccdc11 causes defects in LR patterning, recapitulating the patient phenotype. Upon Ccdc11 depletion, monociliated cells of the Left–Right Organizer (LRO) exhibit
Saurabh S. Kulkarni   +9 more
wiley   +1 more source

SEC‐SAXS/MC Ensemble Structural Studies of the Microtubule Binding Protein Cdt1 Show Monomeric, Folded‐Over Conformations

open access: yesCytoskeleton, EarlyView.
ABSTRACT Cdt1 is a mixed folded protein critical for DNA replication licensing and it also has a “moonlighting” role at the kinetochore via direct binding to microtubules and the Ndc80 complex. However, it is unknown how the structure and conformations of Cdt1 could allow it to participate in these multiple, unique sets of protein complexes.
Kyle P. Smith   +9 more
wiley   +1 more source

Research status of regenerative difficulties after central nervous system injury. [PDF]

open access: yesRegen Ther
Fu Y   +7 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy