Results 181 to 190 of about 225,378 (345)
Targeting Microtubules by Natural Agents for Cancer Therapy
Eiman Mukhtar, V. Adhami, H. Mukhtar
semanticscholar +1 more source
Ubiquitin‐mediated selective autophagy plays a critical role in antiviral innate immunity. The study shows that upon RNA virus infection, cytoplasmic API5 undergoes SRPK1‐dependent phosphorylation at S464, which in turn suppresses p62 K141 ubiquitination‐dependent autophagy.
Tingjuan Deng+10 more
wiley +1 more source
Active spiralling of microtubules driven by kinesin motors. [PDF]
Ng'ang'a DK+3 more
europepmc +1 more source
Assembly of microtubules from preformed, ring‐shaped protofilaments and 6‐s tubulin [PDF]
Harold Erickson
openalex +1 more source
Noninvasive and sensitive detection of tau protein dynamics across developmental stages and APOE genotypes remain a challenge in Alzheimer's disease (AD) research. This study reveals the dynamics of tau secretion in label‐free manner using surface‐enhanced Raman spectroscopy (SERS) and human cerebral organoids (hCOs). This study provides novel insights
Yongjae Jo+11 more
wiley +1 more source
Microtubules in Martini: Parameterizing a heterogeneous elastic-network towards a mechanically accurate microtubule. [PDF]
Sahoo A, Hanson SM.
europepmc +1 more source
SYNTHESIS AND STORAGE OF MICROTUBULE PROTEINS BY SEA URCHIN EMBRYOS [PDF]
Rudolf A. Raff+3 more
openalex +1 more source
This study identifies PRMT3‐mediated H4R3me2a as a critical driver of tau hyperphosphorylation in primary age‐related tauopathy. Mechanistic insights reveal that the PRMT3/H4R3me2a/miR‐448 axis suppresses IGF1R expression via epigenetic regulation, further dysregulating the PI3K/AKT/GSK3β pathway.
Haotian Liu+9 more
wiley +1 more source