Results 191 to 200 of about 242,523 (302)

Neuroaxonal Dystrophy With Osteopetrosis Associated With a Novel Biallelic Nonsense Homozygous Variant in BORCS5

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Neuroaxonal dystrophy (NAD) with osteopetrosis syndrome (OMIM # 600329) was first reported in a consanguineous Moroccan Jewish family. However, to date, no genetic variant has been linked to this disease. We report on sibs, born to consanguineous Pakistani parents identified prenatally with cerebral ventriculomegaly and agenesis of the corpus ...
Yael Fisher, Orli Greenberg, Patrick Shannon, Andrea Staines, Bobbi McGivern, Melanie Patricia Napier, David Chitayat   +6 more
wiley   +1 more source

Evidence for rapid structural and functional changes of the melanophore microtubule-organizing center upon pigment movements [PDF]

, 1979
Manfred Schliwa, Ursula Euteneuer, Wilhelm Herzog, K. Weber   +3 more
openalex   +1 more source

A novel MAP7D1 mutation causes mitotic defects and RPS14 accumulation in Shwachman-Diamond syndrome patient cells.

Dis Model Mech
Kucukvardar S, Karabay A.
europepmc   +1 more source

Maspin/SerpinB5 is a cytoskeleton-binding protein that regulates epithelial cell shape. [PDF]

Commun Biol
da Silva LE, Paim LMG, Lyalina T, Menezes APJ, da Cunha JPC, Bechstedt S, Cella N.   +6 more
europepmc   +1 more source

Transplanting neural stem cells overexpressing miRNA‐21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28‐let‐7 signaling pathway

Animal Models and Experimental Medicine, EarlyView.
Abstract Background Intracerebral hemorrhage (ICH) remains a devastating neurological disorder with limited therapeutic options. Neural stem cell (NSC)‐based therapies have emerged as a potential regenerative approach, yet the molecular mechanisms regulating NSC behavior require further elucidation.
Wei Dai, Yongxia Li, Jiarui Du, Gang Shen, Meimei Fan, Zuopeng Su, Fulin Xu, Fang Yuan   +7 more
wiley   +1 more source

SOX6 enhances vascular smooth muscle cell phenotypic switching and elevates blood pressure by activating autophagy

Animal Models and Experimental Medicine, EarlyView.
Sox6 expression is elevated in hypertensive conditions and promotes vascular smooth muscle cell phenotypic switching through autophagy activation. Using gain‐ and loss‐of‐function approaches both in vitro and in vivo, we demonstrate that Sox6 regulates blood pressure and vascular remodeling, highlighting its potential as a novel therapeutic target for ...
Qianhui Ling, Xilan Dong, Liyan Mao, Chengjun Huang, Linjing Cong, Haizeng Zhang, Jun Cai, Zhenzhen Chen   +7 more
wiley   +1 more source

Mechanisms and Management of Albumin-Paclitaxel-Induced Peripheral Neuropathy in Breast Cancer. [PDF]

Breast Cancer (Dove Med Press)
Xu X, Han Q, Qiu S, Gao S, Ren C, Li X.
europepmc   +1 more source

The Scale of Neurodegeneration in Moderate‐to‐Severe Traumatic Brain Injury: A Systematic Review of Longitudinal Studies

Annals of Neurology, EarlyView.
Synthesis of Literature: Neurodegeneration in Moderate‐Severe TBI. Objective Although moderate‐to‐severe traumatic brain injury (msTBI) was once considered a static neural event following resolution of acute injuries, numerous studies now demonstrate progressive losses to volume and white matter integrity in the months and years postinjury, leading to ...
Bhanu Sharma, Leanne Monteiro, Alana Changoor, Brenda Colella, Robin Green   +4 more
wiley   +1 more source

Super‐Resolution Axial Imaging for Quantifying Piconewton Traction Forces in Live Cells

Angewandte Chemie, EarlyView.
We introduce metal‐induced energy transfer‐based tension probe microscopy (MIET‐TPM), a hybrid imaging approach that combines MIET with DNA‐based molecular tension probes to map piconewton cellular traction forces with nanometer axial resolution. This method enables simultaneous visualization of integrin forces and membrane topography in live cells ...
Dong‐Xia Wang, José Ignacio Gallea, De‐Ming Kong, Jörg Enderlein, Tao Chen   +4 more
wiley   +2 more sources

Active spiralling of microtubules driven by kinesin motors. [PDF]

Sci Rep
Ng'ang'a DK, Kang'iri SM, Hess H, Nitta T.   +3 more
europepmc   +1 more source