Results 191 to 200 of about 249,538 (351)

Mechanotransduction in Shaping Immunity: Pathways, Crosstalk, and Pathophysiological Relevance

Advanced Science, EarlyView.
This review comprehensively summarizes the role of mechanotransduction in shaping immunity. It details how immune cells respond to biomechanical cues via mechanotransduction cascades and emphasizes the mechanical crosstalks within the immune microenvironment. The emerging significance of mechanoimmunology in both health and diseases is also highlighted.
Ruijiao Yan, Yuyu Li, Shuo Chen, Li Zhu, Chenchen Zhou, Jianwei Chen, Shujuan Zou, Xianglong Han   +7 more
wiley   +1 more source

Comparison of the Microtubule Proteins of Neuroblastoma Cells, Brain, and Chlamydomonas Flagella

, 1971
J.B. Olmsted, George B. Witman, Kathryn E. Carlson, Joel L. Rosenbaum   +3 more
openalex   +1 more source

Carbon Monoxide Nanomodulator Reverses Ischemia‐Reperfusion Injury in Stroke: A Novel Dual‐Channel Therapy Mode of Co‐driving Neuroprotection and Neurogenesis

Advanced Science, EarlyView.
This work develops a biomimetic and reactive oxygen species‐activated carbon monoxide (CO) nanogenerator to penetrate blood‐brain barrier, arrive in stroke‐affected regions, and release CO in a controlled manner for an innovative dual‐channel therapy strategy via co‐driving neuroprotection and neurogenesis.
Xuegang Niu, Bin Gao, Hongyi Huang, Zesheng Li, Yibin Zhang, Quanlei Liu, Chao Zhang, Yang Dai, Jinkun Xu, Mingshan Liu, Yuanyuan Zhang, Yihe Wang, Penghu Wei, Yuanxiang Lin, Yongzhi Shan, Yumin Luo, Dezhi Kang, Guoguang Zhao   +17 more
wiley   +1 more source

Consciousness and spintronic coherence in microtubules. [PDF]

Commun Integr Biol
Beshkar M.
europepmc   +1 more source

Nortriptyline Inhibits Lysosomal Exocytosis‐Mediated SASP During Gastric Cancer Progression via Targeting HOXA1‐PITX2 Phase Separation

Advanced Science, EarlyView.
This study identifies that HOXA1 facilitates transcriptional activity of PITX2 in liquid condensates, resulting in up‐regulation of MCOLN1 and RAB3A followed by lysosomal exocytosis of LGALS1 and IGFBP7 from senescent cells, thus activating AKT signaling and EMT.
Yi Zhou, Chunhui Yang, Xinyue Li, Xiaojing Wang, Wanju Jiao, Xiaolin Wang, Jiaying Qu, Bosen Zhao, Shunchen Zhou, Qiangsong Tong, Liduan Zheng   +10 more
wiley   +1 more source

Isolation of Microtubule Protein from Cultured Mouse Neuroblastoma Cells [PDF]

, 1970
J.B. Olmsted, Kathryn E. Carlson, Robert J. Klebe, F.H. Ruddle, Joel L. Rosenbaum   +4 more
openalex   +1 more source

Autophagy‐Targeting Fe–Cu Nanozyme for Tumor Immune Microenvironment Remodeling and Image‐Guided Cancer Immunotherapy

Advanced Science, EarlyView.
In this study, a multifunctional iron‐copper metal–organic framework nanozyme platform co‐delivering chloroquine and perfluorohexane is engineered to circumvent tumor immune evasion by disrupting autophagic flux and restoring major histocompatibility complex class I presentation. This dual‐action nanoplatform orchestrates synergistic autophagy blockade
Li Yan, Chao Chen, Yu Liang, Xiaowan Huang, Jieying Qian, Hao Zhang, Li Zhang, Yingjia Li, Yunjiao Zhang   +8 more
wiley   +1 more source

Meiotic progression in multinuclear mouse spermatocytes without the spindle pole clustering motor protein KIFC1 or cytokinesis forms single-cell late-stage spermatids. [PDF]

Sci Rep
Simerly C, Hartnett C, Zyhowski A, Robertson E, Harrison C, Cho IK, Easley C, Schatten G.   +7 more
europepmc   +1 more source

Interaction of viomycin and aminoglycoside antibiotics with tubulin and microtubules.

, 1978
Tetsu Akiyama, Kenji Tanaka, Nobuo Tanaka, Yoshiaki Nonomura   +3 more
openalex   +2 more sources

Structure of cortical microtubule arrays in plant cells [PDF]

, 1978
A. R. Hardham, BE Gunning
openalex   +1 more source