Results 11 to 20 of about 193,314 (299)
INOCA/ANOCA: Mechanisms and novel treatments
Angina or ischemia with no obstructive coronary disease (ANOCA/INOCA) is a common but under-treated condition due to poorly understood pathophysiologic mechanisms, limited diagnostic tools, and lack of proven targeted therapy.
Namrita D. Ashokprabhu +3 more
doaj +1 more source
Coronary Microvascular Dysfunction: Epidemiology, Clinical Presentation, Diagnosis and Treatment
In a significant number of patients with symptoms of angina pectoris or myocardial infarction with ischemic changes in the myocardium, according to the results of instrumental research methods, there is no hemodynamically significant stenosis of the ...
E. L. Trisvetova
doaj +1 more source
BackgroundUp to 50% of acute myocardial infarction (MI) patients present with microvascular dysfunction, after a successful percutaneous coronary intervention (PCI), which leads to worse clinical outcomes.
Marta Silva +12 more
doaj +1 more source
Microvascular Dysfunction in Hypertrophic Cardiomyopathy
Myocardial ischemia is an established pathophysiological feature of hypertrophic cardiomyopathy (HCM) that impacts various clinical features, including heart failure (HF) and sudden cardiac death (SCD). The major determinant of myocardial ischemia in HCM is coronary microvascular dysfunction (CMD) in the absence of epicardial coronary artery ...
Francesco Pelliccia +3 more
openaire +2 more sources
Coronary Microvascular Dysfunction, Microvascular Angina, and Management [PDF]
Recent analyses have found that coronary microvascular dysfunction (CMD) portends a poor prognosis in patients with and without obstructive epicardial coronary artery disease (CAD). Chest pain in the absence of epicardial CAD is a common entity. Angina caused by CMD, microvascular angina (MVA), is often indistinguishable from that caused by obstructive
Adrián I, Löffler, Jamieson M, Bourque
openaire +2 more sources
Coronary Microvascular Dysfunction
-
Paolo G. Camici 1 +2 more
+5 more sources
Coronary microvascular dysfunction: an update [PDF]
Many patients undergoing coronary angiography because of chest pain syndromes, believed to be indicative of obstructive atherosclerosis of the epicardial coronary arteries, are found to have normal angiograms. In the past two decades, a number of studies have reported that abnormalities in the function and structure of the coronary microcirculation may
Crea, Filippo +2 more
openaire +4 more sources
Impaired Coronary and Renal Vascular Function in Spontaneously Type 2 Diabetic Leptin-Deficient Mice. [PDF]
Type 2 diabetes is associated with macro- and microvascular complications in man. Microvascular dysfunction affects both cardiac and renal function and is now recognized as a main driver of cardiovascular mortality and morbidity.
Helena U Westergren +9 more
doaj +1 more source
Small vessel disease: Connections between the kidney and the heart
Small vessel disease is characterized by global dysfunction of the microvascular system leading to reduced perfusion of various organ systems. The kidney is significantly vulnerable for microvascular dysfunction given its intricate capillary network and ...
Jacob K. Meariman +4 more
doaj +1 more source
Role of coronary microvascular dysfunction in heart failure with preserved ejection fraction [PDF]
Heart failure with preserved ejection fraction (HFpEF) is one of the greatest unmet needs in modern medicine. The lack of an appropriate therapy may reflect the lack of an accurate comprehension of its pathophysiology.
Francesco Tona +3 more
doaj +1 more source

