Results 31 to 40 of about 193,314 (299)

International prospective cohort study of microvascular angina – Rationale and design

International Journal of Cardiology: Heart & Vasculature, 2020
Background: Patients with signs and symptoms of myocardial ischemia and non-obstructive coronary artery disease (CAD) frequently have coronary functional abnormalities, including coronary microvascular dysfunction. Those with the latter are grouped under
Akira Suda, Jun Takahashi, John F. Beltrame, Colin Berry, Paolo G. Camici, Filippo Crea, Javier Escaned, Tom Ford, Juan Carlos Kaski, Takahiko Kiyooka, Puja K. Metha, Peter Ong, Yukio Ozaki, Carl Pepine, Ornella Rimoldi, Basmah Safdar, Udo Sechtem, Kenichi Tsujita, Eric Yii, C. Noel Bairey Merz, Hiroaki Shimokawa   +20 more
doaj   +1 more source

Diabetes, hypertension, and cardiovascular disease: clinical insights and vascular mechanisms [PDF]

, 2018
Hypertension and type 2 diabetes are common comorbidities. Hypertension is twice as frequent in patients with diabetes compared with those who do not have diabetes.
Guzik, Tomasz J., Petrie, John R., Touyz, Rhian M.   +2 more
core   +1 more source

Microvascular and Endothelial Dysfunction in Prediabetes

Life, 2023
Prediabetes is a significant metabolic status since there is high potential for future progression of diabetes mellitus (DM). People with prediabetes are at increased risk of cardiovascular disease (CVD) and mortality.
Stamatina Lamprou, Nikolaos Koletsos, Gesthimani Mintziori, Panagiota Anyfanti, Christina Trakatelli, Vasileios Kotsis, Eugenia Gkaliagkousi, Areti Triantafyllou   +7 more
doaj   +1 more source

Diabetes mellitus and ischemic heart disease. the role of ion channels [PDF]

, 2018
Diabetes mellitus is one the strongest risk factors for cardiovascular disease and, in particular, for ischemic heart disease (IHD). The pathophysiology of myocardial ischemia in diabetic patients is complex and not fully understood: some diabetic ...
De Marchis, Marialaura, D’Amato, Andrea, Fedele, Francesco, Mancone, Massimo, Netti, Lucrezia, Palmirotta, Raffaele, Pucci, Mariateresa, Severino, Paolo, Volterrani, Maurizio   +8 more
core   +2 more sources

Association of PET-measured myocardial flow reserve with echocardiography-estimated pulmonary artery systolic pressure in patients with hypertrophic cardiomyopathy [PDF]

, 2019
BackgroundPulmonary hypertension (PH) is a known complication of HCM and is a strong predictor of mortality. We aim to investigate the relationship between microvascular dysfunction measured by quantitative PET and PH in HCM patients.MethodsEighty-nine ...
Leal, Jeffrey P, Liu, Min, Pomper, Martin G, Tsui, Benjamin M. W., Wong, Dean F, Zhao, Min, Zhou, Yun   +6 more
core   +3 more sources

Coronary microvascular dysfunction as a chronic inflammatory state: Is there a role for omega-3 fatty acid treatment?

American Heart Journal Plus, 2022
Coronary microvascular dysfunction is a ubiquitous pathologic process that is operational in ischemia with no obstructive coronary artery disease and other cardiovascular disorders including heart failure with preserved ejection fraction. It may, in fact,
Ellen C. Keeley, Eileen M. Handberg, Janet Wei, C. Noel Bairey Merz, Carl J. Pepine   +4 more
doaj   +1 more source

Serum uric acid as a marker of microvascular damage in systemic sclerosis patients [PDF]

, 2016
Background: Microvascular damage of skin and internal organs is a hallmark of systemic sclerosis (SSc). Serum uric acid (UA) represents a marker of inflammation and endothelial dysfunction.
Amoroso, Antonio, Barbano, Biagio, Barilaro, Giuseppe, Cianci, Rosario, Di Mario, Francesca, Gasperini, Maria Ludovica, Gigante, Antonietta, Quarta, Silvia, Romaniello, Antonella, Rosato, Edoardo   +9 more
core   +1 more source

Neutrophil extracellular traps drive intestinal microvascular endothelial ferroptosis by impairing Fundc1-dependent mitophagy

Redox Biology, 2023
Microvascular endothelial damage caused by intestinal ischemia‒reperfusion (II/R) is a primary catalyst for microcirculation dysfunction and enterogenous infection.
Chengnan Chu, Xinyu Wang, Chao Yang, Fang Chen, Lin Shi, Weiqi Xu, Kai Wang, Baochen Liu, Chenyang Wang, Dongping Sun, Weiwei Ding   +10 more
doaj   +1 more source

Coronary endothelial dysfunction appears to be a manifestation of a systemic process: A report from the Women's Ischemia Syndrome Evaluation - Coronary Vascular Dysfunction (WISE-CVD) study.

PLoS ONE, 2021
BackgroundCoronary microvascular dysfunction (CMD) is prevalent in symptomatic women with ischemia but no obstructive coronary artery disease (INOCA). Urine albumin-creatinine ratio (UACR) is a measure of renal microvascular endothelial dysfunction. Both
Sawan Jalnapurkar, Sofy Landes, Janet Wei, Puja K Mehta, Chrisandra Shufelt, Margo Minissian, Carl J Pepine, Eileen Handberg, Galen Cook-Wiens, George Sopko, C Noel Bairey Merz   +10 more
doaj   +1 more source

Microvascular dysfunction following cardiopulmonary bypass plays a central role in postoperative organ dysfunction

Frontiers in Medicine, 2023
Despite significant advances in surgical technique and strategies for tissue/organ protection, cardiac surgery involving cardiopulmonary bypass is a profound stressor on the human body and is associated with numerous intraoperative and postoperative ...
Shawn Kant, Debolina Banerjee, Sharif A. Sabe, Frank Sellke, Jun Feng   +4 more
doaj   +1 more source