Results 31 to 40 of about 203,456 (311)

The XIIIth Banff Conference on Allograft Pathology: The Banff 2015 Heart Meeting Report: Improving Antibody-Mediated Rejection Diagnostics: Strengths, Unmet Needs, and Future Directions. [PDF]

, 2017
The 13th Banff Conference on Allograft Pathology was held in Vancouver, British Columbia, Canada from October 5 to 10, 2015. The cardiac session was devoted to current diagnostic issues in heart transplantation with a focus on antibody-mediated rejection
Angelini, A, Berry, GJ, Bruneval, P, Dragun, D, Duong Van Huyen, JP, Fedrigo, M, Haas, M, Loupy, A, Mengel, M, Miller, D, Potena, L, Reed, EF, Reinsmoen, N, Revelo, P, Smith, RN, Tebutt, S, Thum, T, West, L, Zeevi, A   +18 more
core   +1 more source

p22phox C242T Single-Nucleotide Polymorphism Inhibits Inflammatory Oxidative Damage to Endothelial Cells and Vessels. [PDF]

, 2016
BACKGROUND: The NADPH oxidase, by generating reactive oxygen species, is involved in the pathophysiology of many cardiovascular diseases and represents a therapeutic target for the development of novel drugs.
Brooks, G, Fan, LM, Ghazaly, MM, Howlin, B, Krönke, M, Li, J-M, Meijles, DN   +6 more
core   +1 more source

Effect of tryptase on mouse brain microvascular endothelial cells via protease-activated receptor 2

Journal of Neuroinflammation, 2018
Background Mast cells (MCs), the ‘first responders’ in brain injury, are able to disrupt the blood–brain barrier (BBB), but the underlying mechanism is not well understood. Tryptase is the most abundant MC secretory product. Protease-activated receptor 2
Qin Zhou, Yi-wei Wang, Peng-fei Ni, Yi-nan Chen, Hong-quan Dong, Yan-ning Qian   +5 more
doaj   +1 more source

Verocytotoxin-Induced Apoptosis of Human Microvascular Endothelial Cells [PDF]

Journal of the American Society of Nephrology, 2001
Abstract. The pathogenesis of the epidemic form of hemolytic uremic syndrome is characterized by endothelial cell damage. In this study, the role of apoptosis in verocytotoxin (VT)-mediated endothelial cell death in human glomerular microvascular endothelial cells (GMVEC), human umbilical vein endothelial cells, and foreskin ...
Pijpers, A.H.J.M., Setten, P.A. van, Heuvel, L.P.W.J. van den, Assmann, K.J.M., Dijkman, H.B.P.M., Pennings, A.H.M., Monnens, L.A.H., Hinsbergh, V.W.H. van   +7 more
openaire   +4 more sources

Mechanistic Pathogenesis of Endothelial Dysfunction in Diabetic Nephropathy and Retinopathy

Frontiers in Endocrinology, 2022
Diabetic nephropathy (DN) and diabetic retinopathy (DR) are microvascular complications of diabetes. Microvascular endothelial cells are thought to be the major targets of hyperglycemic injury.
Jing Yang, Jing Yang, Jing Yang, Jing Yang, Zhangsuo Liu, Zhangsuo Liu, Zhangsuo Liu, Zhangsuo Liu   +7 more
doaj   +1 more source

Uptake and cytotoxicity of citrate-coated gold nanospheres : comparative studies on human endothelial and epithelial cells [PDF]

, 2012
The use of gold nanoparticles (AuNPs) for diagnostic applications and for drug and gene-delivery is currently under intensive investigation. For such applications, biocompatibility and the absence of cytotoxicity of AuNPs is essential. Although generally
Couraud, Pierre-Olivier, Freese, Christian, Gibson, Matthew I., Kirkpatrick, C. J. (C. James), Romero, Ignacio A., Uboldi, Chiara, Unger, Ronald E., Weksler, Babette B.   +7 more
core   +7 more sources

Anti-endothelial cell antibodies in pathogenesis of vasculitis

Frontiers in Immunology
Vasculitis is a group of syndromes characterized by inflammation, presence of autoantibodies and endothelial cells (ECs) damage, which lead to stenosis or occlusion of the vascular lumen. Anti-endothelial cell antibodies (AECAs) are a heterogeneous group
Tian Zhang, Tian Zhang, Tian Zhang, Liqun Li, Shengshi Huang, Shengshi Huang, Shengshi Huang, Maria N. Starodubtseva, Maria N. Starodubtseva, Ju Liu, Ju Liu, Ju Liu   +11 more
doaj   +1 more source

Human Liver Endothelial Cells, But Not Macrovascular or Microvascular Endothelial Cells, Engraft in the Mouse Liver

Cell Transplantation, 2013
Liver cell transplantation has had limited clinical success so far, partly due to poor engraftment of hepatocytes. Instead of hepatocytes. other cell types, such as endothelial cells, could be used in ex vivo liver gene therapy.
Ebtisam El Filali, Johan K. Hiralall, Henk A. Van Veen, Donna B. Stolz, Jurgen Seppen   +4 more
doaj   +1 more source

The marginated pool [PDF]

, 2002
The pulmonary circulation harbors a large intravascular reservoir of leukocytes refered to as the Marginated Pool. This marginated pool is balanced by propeling and retaining forces acting on leukocytes during their passage through the pulmonary ...
Goetz, Alwin Eduard, Kuebler, Wolfgang M.   +1 more
core   +1 more source

Microvascular Endothelial Cell Culture.

Journal of Investigative Dermatology, 1989
Microvascular endothelial cells play a central role in inflammation, tumor metastasis, and wound healing. Methods to study these processes in vitro using cells isolated from adult skin, from the inner and the outer segments of the neontal foreskin, and from experimental animals are reviewed.
openaire   +2 more sources