Results 131 to 140 of about 15,195 (308)
The emerging role of exosome and microvesicle‐ (EMV‐) based cancer therapeutics and immunotherapy
International Journal of Cancer, 2017 There is an urgent need to develop new combination therapies beyond existing surgery, radio‐ and chemo‐therapy, perhaps initially combining chemotherapy with the targeting specificities of immunotherapy.
Colin E. Moore +3 more
semanticscholar +1 more source
Exploration, EarlyView.An acid‐cleavable Tf‐modified engineering exosome‐based brain‐targeting delivery system (ACTE) was proposed using metabolic glycoengineering and bioorthogonal click chemistry, enabling co‐delivery of siTGF‐β and DOX for GBM treatment. ACTE was featured by higher BBB transcytosis efficiency and hierarchical targeting delivery to GBM cells.
Jun Yang +14 more
wiley +1 more source
Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities. [PDF]
ESC Heart FailAbstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
D'Italia G, Schroen B, Cosemans JMEM.
europepmc +2 more sources
Microvesicles are messengers [PDF]
Seminars in Immunopathology, 2011 Schifferli,, Jürg, A.
openaire +4 more sources
Critical Care Medicine, 2016 Objectives: To identify plasma biomarkers that can be early predictors of mortality in critically ill patients with primary influenza A/H1N1. Design: A prospective, multicenter, case-cohort pilot study. Setting: Three academic ICUs.
M. Rondina +3 more
semanticscholar +1 more source
Synthetic Biology‐Based Engineering Cells for Drug Delivery
Exploration, EarlyView.Synthetic biology‐based therapeutic cells for drug delivery: Engineered cells effectively transport and release drugs through their intelligence and controllability, such as feedback pathways and external stimuli (e.g., light and ultrasound). The integration of nanotechnology, including nanoparticles, biofilms, and artificial cells, enhances ...
Wenzhe Yi +4 more
wiley +1 more source
CLEC2 and CLEC5A: Pathogenic Host Factors in Acute Viral Infections
Frontiers in Immunology, 2019 The protective roles of endosomal toll-like receptors (TLRs) and cytosolic nucleic acid sensors are well elucidated, but the pathogenic host factors during viral infections remain unclear. Spleen tyrosine kinase (Syk)-coupled C-type lectins (CLECs) CLEC2
Pei-Shan Sung +4 more
doaj +1 more source
Photochemistry and Photobiology, 2017 Ultraviolet B radiation (UVB) exerts profound effects on human skin. Much is known regarding the ability of UVB to generate a plethora of bioactive agents ranging from cytokines and other bioactive proteins, lipid mediators and microRNAs.
Katherine E. Fahy +7 more
semanticscholar +1 more source
Interdisciplinary Medicine, EarlyView.This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao +6 more
wiley +1 more source
Acupuncture and vitamin B12 injection for Bell′s palsy: no high-quality evidence exists
Neural Regeneration Research, 2015 OBJECTIVE: To assess the efficacy of acupuncture combined with vitamin B 12 acupoint injection versus acupuncture alone to reduce incomplete recovery in patients with Bell′s palsy.
Li-li Wang +4 more
doaj +1 more source