Results 111 to 120 of about 8,491 (234)

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

CCL26‐Mediated Modulation of Endothelial Secretome by Hypoxia‐Induced Tumor‐Derived Exosomes Enhances Metastatic Progression in Head and Neck Cancer

Head &Neck, Volume 48, Issue 9, Page 2377-2393, September 2026.
ABSTRACT Background Tumor cells adapt to hypoxia by releasing hiTDExs enriched with bioactive molecules that modulate endothelial behavior and promote tumor progression. This study aimed to characterize how hypoxia‐induced HNSCC exosomes reshape the endothelial secretome and contribute to metastatic potential.
Ozel Capik, Sevil Tekman, Betul Gundogdu, Ahsen Kilic, Rumeysa Polat, Omer Aydin, Omer Faruk Karatas   +6 more
wiley   +1 more source

A Review of the Therapeutic Potential of Stem Cell‐Derived Nanocarriers to Treat Neurological Disorders

ChemistryOpen, Volume 15, Issue 9, September 2026.
Neurological disorders (NDs) are characterized by substantial loss of specific neurons, with Alzheimer's and Parkinson's diseases being the most frequent NDs and nearly 99% of all “foreign substances” are prohibited from entering the brain by the blood‐brain barrier (BBB) and the blood‐cerebrospinal fluid barrier (CFB).
Nnamdi Ikemefuna Okafor, Ahmed Abdelgader, Magdi Abobaker, Yahya E. Choonara   +3 more
wiley   +1 more source

What Is Your Diagnosis? Abdominal Wall Mass in a Dog

Veterinary Clinical Pathology, EarlyView.
Morwenna Rodgers, Slavomira Necova, Cassia Hare   +2 more
wiley   +1 more source

Nanotechnology‐Based Immunostimulants in Aquaculture: Mechanisms, Advances and Practical Applications

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Nano‐immunostimulants improve fish health through targeted and controlled delivery of immunostimulatory compounds. Biodegradable polymeric and lipid‐based nanocarriers enhance immune responses, bioavailability and disease resistance while reducing antibiotic dependence and environmental impact.
Mustafa Öz, Enes Üstüner
wiley   +1 more source

hTERT Immortalization Stabilizes Human Umbilical Cord MSCs and Maintains Their Small Extracellular Vesicles With Preserved Immunomodulatory Activity and Primordial Follicle‐Activating Capacity

Aging Cell, Volume 25, Issue 9, September 2026.
hTERT immortalization stabilizes hUCMSC‐derived sEV function by alleviating cellular senescence and preserving young‐like cargo profiles. H11‐sEVs retain immunomodulatory activity, primordial follicle‐activating capacity, and ovarian protective effects.
Yating Chen, Wei Liu, Ying Tian, Xinyu Wang, Haonan Fan, Mingyu Yang, Feiyang Diao, Jing Li   +7 more
wiley   +1 more source

In Vitro Sperm–Epididymosomes Interaction Immediately Before Fertilization Changes Sperm Fertility Potential

Andrology, Volume 14, Issue 6, Page 1757-1770, September 2026.
ABSTRACT Background Sperm acquire fertility ability during epididymal maturation mainly in the epididymal caput and corpus, and once matured, are stored in the epididymal cauda. During storage, interactions with cauda epididymosomes (epEVs) may influence sperm fertility potential; however, the role of such interactions on sperm fertility remains ...
Maíra Bianchi Rodrigues Alves, Maria Alice de Almeida, Ana Beatriz Bossois Moura, Laura Gabrielli Haupenthal, Raissa Braido Rangel, Flávio Vieira Meirelles, Juliano Coelho da Silveira, Felipe Perecin   +7 more
wiley   +1 more source

From Tumour to Bloodstream: Advancing PD‐L1 Testing With Liquid Biopsies in Non‐Small Cell Lung Cancer

Cytopathology, Volume 37, Issue 5, Page 438-448, September 2026.
This review explores liquid biopsy as a complementary approach to tissue‐based PD‐L1 assessment in advanced NSCLC treated with immune checkpoint inhibitors. Focusing on circulating tumour cells, extracellular vesicles, and circulating tumour DNA, it summarises current evidence, technical challenges, and future perspectives for personalised ...
R. Leporati, V. Callegari, A. Ancora, M. Palmieri, B. Riccò, E. Cabitza, L. Trudu, K. Di Emidio, C. Chiavelli, A. Eccher, I. Mastrolia, V. Catani, S. Bettelli, G. Guaitoli, M. Dominici, F. Bertolini   +15 more
wiley   +1 more source

Neutrophil Secretory Proteins Inhibit Calcium Oxalate Crystallisation and Crystal Growth, but Promote Crystal Aggregation

Immunology, Volume 179, Issue 1, Page 101-117, September 2026.
Calcium oxalate monohydrate (COM) crystals cause changes in the secretion of 29 proteins from neutrophil‐like cells, including those involved in neutrophil immune activation and intracellular metabolic adaptation. The neutrophil secreted proteins (secretome) also inhibit calcium oxalate crystallisation and crystal growth, but promote crystal ...
Chanettee Lertprapai, Paleerath Peerapen, Visith Thongboonkerd   +2 more
wiley   +1 more source

Do Exercise‐Induced Extracellular Vesicles Carry Cognitive Benefits to the Brain?

Traffic, Volume 27, Issue 3, September 2026.
Exercise‐induced muscle‐brain communication mediated by extracellular vesicles. Physical exercise stimulates skeletal muscle to release extracellular vesicles (EVs) into the circulation. These vesicles may reach the brain and transfer bioactive cargo such as miRNA, thereby supporting neuronal function and brain homeostasis and potentially protecting ...
Oliver K. Fuller, Thierry Galli
wiley   +1 more source