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Inflammatory skin diseases comprise a group of skin conditions characterized by damage to skin function due to overactive immune responses. These disorders not only impair the barrier function of the skin but also deteriorate the quality of life and ...
Qi Xiang +9 more
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Background Tissue factor (TF)-rich cancer microvesicles are correlated with thrombosis risk. Intrinsic coagulation factors are also associated with the risk of thrombosis in cancer patients.
Yen-Ting Chang +11 more
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, 2018 Zielsetzung Dem Endothel wird eine zentrale Rolle in der Pathogenese des septischen Schocks zugeschrieben. Da bei diversen Erkrankungen, bei denen eine Mitbeteiligung des Endothels vorhanden ist, erhöhte Level endothelialer Mikrovesikel (MV) gefunden wurden, werden diese als Surrogatparameter angesehen, die den Zustand des Endothels widerspiegeln. Ziel
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Snakebites and microvesicles: Popping bubbles [PDF]
Research and Practice in Thrombosis and Haemostasis, 2019 Bos, M.H.A., Versteeg, H.H.
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Arteriosclerosis, Thrombosis, and Vascular Biology, 2007 OBJECTIVE: Although erythrocytes have been suggested to play a role in blood clotting, mediated through phosphatidylserine (PS) exposure and/or PS-bearing microvesicle generation, an endogenous substance that triggers the membrane alterations leading to ...
Yi-Sook Jung +2 more
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Blood, 2018 Key PointsLactadherin promotes the clearance of circulating microvesicles through phagocytosis. Promoting microvesicle clearance prevents coagulopathy, reduces cerebral edema, and improves neurological function in severe TBI mice.
Jing-Fei Dong +2 more
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Mechanobiology of microvesicle release, uptake, and microvesicle-mediated activation
2020Microvesicles are small, membrane-bound vesicles that are shed from the plasma membrane of cells into the extracellular space. Microvesicles contain a variety of cargo not typically thought to be released from cells, including receptor tyrosine kinases, cytosolic signaling proteins, and microRNAs, which are transferred from donor cells to recipient ...
Samantha C, Schwager +1 more
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Microvesicles in Health and Disease
Archivum Immunologiae et Therapiae Experimentalis, 2012Microvesicles (or MVs) are plasma membrane-derived vesicles released from most eukaryotic cells constitutively during early apoptosis or at higher levels after chemical or physical stress conditions. This review looks at some of the functions of MVs in terms of intercellular communication and ensuant signal transduction, including the transport of ...
Jameel M, Inal +6 more
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Acute Ethanol Exposure Stimulates Microvesicle Particle Generation in Keratinocytes
Toxicology Letters, 2022 Ethanol has been demonstrated to exert profound effects upon cells and tissues via multiple mechanisms. One recently appreciated means by which cells can communicate with other cells is via the production and release of extracellular vesicles.
Jeffrey B Travers +2 more
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Tumor-derived microvesicles: The metastasomes
Medical Hypotheses, 2013Metastasis is the leading cause of cancer death, yet it is mechanistically considered a very inefficient process suggesting the presence of some sort of (e.g. systemic) routes for fuelling the process. The pre-metastatic niche formation is described as one such metastasis promoting route.
Ghasemi R +6 more
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