Results 81 to 90 of about 8,491 (234)
CLEC2 and CLEC5A: Pathogenic Host Factors in Acute Viral Infections
Frontiers in Immunology, 2019 The protective roles of endosomal toll-like receptors (TLRs) and cytosolic nucleic acid sensors are well elucidated, but the pathogenic host factors during viral infections remain unclear. Spleen tyrosine kinase (Syk)-coupled C-type lectins (CLECs) CLEC2
Pei-Shan Sung +4 more
doaj +1 more source
Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles
Mass Spectrometry Reviews, EarlyView.ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág +5 more
wiley +1 more source
Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery
Mass Spectrometry Reviews, EarlyView.ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
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Microvesicles are messengers [PDF]
Seminars in Immunopathology, 2011 Schifferli,, Jürg, A.
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Pediatric Discovery, EarlyView.Excessive neutrophil extracellular trap (NET) extrusion (NETosis) links prenatal inflammation to bronchopulmonary dysplasia (BPD) pathogenesis. Treatment with human umbilical cord mesenchymal stem cell‐derived microvesicles suppresses NET formation, reduces lung injury, and promotes alveolarization in a preterm rat model, offering a promising cell‐free
Yi Lu +10 more
wiley +1 more source
Assessing Extracellular Vesicle Proteins as Predictive Biomarkers for Developing Type 1 Diabetes
PROTEOMICS, EarlyView.ABSTRACT Plasma extracellular vesicles (EVs) are considered excellent sources for biomarker discovery since they carry signatures of their cellular origin and disease processes. In this paper, we evaluate the potential of plasma EV proteomics analysis for identifying predictive biomarkers of developing type 1 diabetes (T1D), which results from ...
Panshak P. Dakup +9 more
wiley +1 more source
Impact of Chemotherapy on Extracellular Vesicles: Understanding the Chemo-EVs
Frontiers in Oncology, 2019 Chemotherapy is the standard go-to treatment for cancer besides surgery and radiation. It has recently come to light that the interaction between chemotherapy and the immune system is important in maintaining tumor immunity as well as influencing the ...
Nur' Syahada Ab Razak +3 more
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, 2014 On activation cells shed vesicles from their surface by the process of ectocytosis. These micro-vesicles or Ectosomes express phosphatidyl-serine (PS) on their surface, which can elicit a range of biological effects from immune-suppression to the activation of the clotting and complement pathways.
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Andrology, EarlyView.ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu +8 more
wiley +1 more source
The Journal of Cell Biology, 2002 ![Graphic][1] Melanoma cells can attack using microvesicles loaded with FasL (red). Fais/RUPMelanoma cells send out microvesicles loaded with Fas ligand (FasL) to kill their would-be assassins, according to Stefano Fais (Istituto Superiore di Sanita, Rome, Italy), Licia Rivoltini (
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