Results 131 to 140 of about 8,491 (234)

Microvesicles in sepsis

, 2018
Zielsetzung Dem Endothel wird eine zentrale Rolle in der Pathogenese des septischen Schocks zugeschrieben. Da bei diversen Erkrankungen, bei denen eine Mitbeteiligung des Endothels vorhanden ist, erhöhte Level endothelialer Mikrovesikel (MV) gefunden wurden, werden diese als Surrogatparameter angesehen, die den Zustand des Endothels widerspiegeln. Ziel
openaire   +1 more source

Gabapentin‐Induced Hypoglycemia in a Patient With Pre‐Diabetes: A Case Report and Review of the Literature

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Gabapentin, a γ‐aminobutyric acid (GABA) analogue, is widely prescribed for neuropathic pain and partial seizures. While common adverse effects include somnolence and dizziness, hypoglycemia is rarely reported. A 76‐year‐old woman with hypertension, dyslipidemia, hypothyroidism, and pre‐diabetes (HbA1c 6%) developed recurrent symptomatic ...
Reem Hussain Alamri, Abdullah Ali Alshamrani, Hesham E. Mawar, Suhaib Radi   +3 more
wiley   +1 more source

Receptor-Dependent and -Independent Effects of Hemin on Platelet Plasma Membrane Disintegration. [PDF]

FASEB J
Laspa Z, Rohlfing AK, Hochuli R, Sowa PW, Castor T, Gawaz MP.   +5 more
europepmc   +1 more source

Mesenchymal stem cell‐derived exosomes for cardiac repair: Challenges, standardization gaps and a realistic path to clinical translation

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Mesenchymal stem cell‐derived exosomes (MSC‐sEVs) show preclinical promise for cardiac repair via anti‐inflammatory, anti‐apoptotic, pro‐angiogenic and anti‐fibrotic effects. However, translational hurdles remain, including non‐standardized isolation, unvalidated potency assays, incomplete GMP manufacturing, and lack of completed Phase II/III trials ...
Sakhavat Abolhasani, Yasin Ahmadi, Amin Jalizih   +2 more
wiley   +1 more source

Microvesicle Profiles in Patients with HIV, HBV, and HCV Infections: An Exploratory Pilot Study. [PDF]

Microorganisms
Dryllis G, Fortis SP, Martsoukos N, Pantazatou V, Spyropoulou E, Pontikaki D, Kapatais C, Tsakalis N, Konstantelou A, Trifylli EM, Tsantes AG, Papageorgiou EG, Valsami S, Kapatais A, Kosmopoulou O, Kriebardis AG.   +15 more
europepmc   +1 more source

Role of cancer‐associated fibroblast‐derived exosomal microRNAs in breast cancer progression: A systematic review

Clinical and Translational Discovery, Volume 6, Issue 4, August 2026.
Yy Abstract Background Cancer‐associated fibroblasts (CAFs) are key components of the breast cancer tumor microenvironment and mediate communication with tumor cells through extracellular vesicles carrying microRNAs (miRNAs). These miRNAs may influence breast cancer progression by regulating oncogenic and tumor‐suppressive pathways.
Matine Hajarian‐Rezazadeh, Fatemeh Fattahi, Mahmood Shekari‐Khaniani, Mehdi Khorrami, Akbar Amirfirouzi   +4 more
wiley   +1 more source

Evidence for microvesicle particles and platelet-activating factor as effectors for systemic effects of thermal burn injury. [PDF]

Front Immunol
Parackal AV, Fox RC, Umerani A, Park Y, Johnson RM, Zhang W, Xu Z, Smith AA, Rohan CA, Travers JB.   +9 more
europepmc   +1 more source

Extracellular Vesicles in Acute Myeloid Leukemia: Opportunities and Obstacles for Therapeutic Advancement

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Acute myeloid leukemia (AML) is a disease characterized by uncontrolled proliferation and blocked maturation of hematopoietic stem and progenitor cells. Despite progress in its clinical management, many patients continue to relapse or show limited response to standard therapies, emphasizing the need for novel, safe, and more effective targeted ...
Rongrong Hu, Zaker Ataullev, Luping Lou
wiley   +1 more source

Under Pressure: Rapid Infusion of Stored Whole Blood Alters Coagulation Parameters. [PDF]

J Surg Res
Becker ER, Chae RC, Price AD, Wattley LJ, Schuster RM, Goodman MD, Pritts TA.   +6 more
europepmc   +1 more source

Iron Salts, but Not Iron Oxide Nanoparticles, Drive High‐Yield Production of Iron‐Engineered Extracellular Vesicles

Journal of Extracellular Vesicles, Volume 15, Issue 8, August 2026.
Soluble iron, but not iron oxide nanoparticles, is efficiently routed into extracellular vesicles (EVs) through physiological cargo‐sorting pathways. Prolonged ferric salt incubation combined with turbulence‐based hydrodynamic stimulation drives massive EV secretion and near‐complete intracellular iron transfer via ferritin.
Elliot Thouvenot, Aurore Van de Walle, Jean‐Michel Guigner, Ali Abou‐Hassan, Lorena Martin‐Jaular, Amanda K. A. Silva, Claire Wilhelm   +6 more
wiley   +1 more source