Results 141 to 150 of about 15,195 (308)

UVB Generates Microvesicle Particle Release in Part Due to Platelet‐activating Factor Signaling

Photochemistry and Photobiology, 2016
The lipid mediator platelet‐activating factor (PAF) and oxidized glycerophosphocholine PAF agonists produced by ultraviolet B (UVB) have been demonstrated to play a pivotal role in UVB‐mediated processes, from acute inflammation to delayed systemic ...
J. Bihl, C. Rapp, Yanfang Chen, J. Travers   +3 more
semanticscholar   +1 more source

Circulating Exosomal Proteins as New Diagnostic Biomarkers for Colorectal Cancer (EXOSCOL01): A Pilot Case–Controlled Study Focusing on MMP14 Potential

Journal of Clinical Laboratory Analysis, EarlyView.
New biomarkers are needed to make colorectal cancer (CRC) screening programs more efficient. Cancer cells secrete, in plasma, extracellular vesicles that contain proteins. Matrix Metalloproteinases 14 (MMP14) play a critical role in the initiation and progression of CRC.
Mickaël Barhoum, Sylvie Brassart‐Pasco, Aurélie Dupont‐Deshorgue, Aurore Thierry, Lukshe Kanagaratnam, Bertrand Brassart, Fidy Ramaholimihaso, Damien Botsen, Claire Carlier, Mathias Brugel, Marine Perrier, Laurent Ramont, Olivier Bouché   +12 more
wiley   +1 more source

The Emerging Roles of Extracellular Vesicles As Communication Vehicles within the Tumor Microenvironment and Beyond

Frontiers in Endocrinology, 2017
Tumors evolve in complex and dynamic microenvironments that they rely on for sustained growth, invasion, and metastasis. Within this space, tumor cells and non-malignant cells are in frequent communication.
Ryan Sullivan, Grace Maresh, Xin Zhang, Carlos Salomon, Carlos Salomon, Carlos Salomon, John Hooper, David Margolin, David Margolin, Li Li, Li Li   +10 more
doaj   +1 more source

Local protein dynamics during microvesicle exocytosis in neuroendocrine cells

bioRxiv, 2018
Calcium triggered exocytosis is key to many physiological processes, including neurotransmitter and hormone release by neurons and endocrine cells. Dozens of proteins regulate exocytosis, yet the temporal and spatial dynamics of these factors during ...
Agila Somasundaram, Justin W. Taraska
semanticscholar   +1 more source

In Vitro Assessment of Chitosan‐PEG Hydrogels Enriched with MSCs‐Exosomes for Enhancing Wound Healing

Macromolecular Bioscience, EarlyView.
A novel hydrogel composed of chitosan and polyethylene glycol, integrated with exosomes derived from adipose mesenchymal stem cells, demonstrates enhanced wound healing. This biomaterial promotes endothelial cell migration, reduces oxidative stress, and facilitates angiogenesis.
Masoumeh Ezati, Amir Hashemi, Inna Zumberg, Minoo Partovi Nasr, Zdenka Fohlerova   +4 more
wiley   +1 more source

Mechanisms and modulation of microvesicle uptake in a model of alveolar cell communication

Journal of Biological Chemistry, 2017
Extracellular vesicles, including exosomes and shed microvesicles (MVs), can be internalized by recipient cells to modulate function. Although the mechanism by which extracellular vesicles are internalized is incompletely characterized, it is generally ...
D. J. Schneider, J. Speth, L. Penke, S. Wettlaufer, J. Swanson, M. Peters-Golden   +5 more
semanticscholar   +1 more source

Microfluidic Systems in Cancer Diagnosis: Advancing Exosome and CTC Detection From Laboratory Research to Clinical Application

Nano Select, EarlyView.
Detection of cancer through the identification of EV markers and CTCs using microfluidic systems is rapidly advancing. These markers are typically identified from liquid biopsy samples, which offer a highly favorable alternative to traditional biopsy methods due to their non‐invasive nature.
Bahareh Valinezhad Saghezi, Kamran Mansouri, Rahman Hallaj   +2 more
wiley   +1 more source

Release of cholesterol‐enriched microvesicles from human erythrocytes caused by hypertonic saline at low temperatures [PDF]

, 1979
Tadashi Araki
openalex   +1 more source

Peptidylarginine Deiminases—Roles in Cancer and Neurodegeneration and Possible Avenues for Therapeutic Intervention via Modulation of Exosome and Microvesicle (EMV) Release?

International Journal of Molecular Sciences, 2017
Exosomes and microvesicles (EMVs) are lipid bilayer-enclosed structures released from cells and participate in cell-to-cell communication via transport of biological molecules.
S. Lange, M. Gallagher, Sharad Kholia, Uchini S. Kosgodage, M. Hristova, J. Hardy, J. Inal   +6 more
semanticscholar   +1 more source

The Omics‐Driven Machine Learning Path to Cost‐Effective Precision Medicine in Chronic Kidney Disease

PROTEOMICS, EarlyView.
ABSTRACT Chronic kidney disease (CKD) poses a significant and growing global health challenge, making early detection and slowing disease progression essential for improving patient outcomes. Traditional diagnostic methods such as glomerular filtration rate and proteinuria are insufficient to capture the complexity of CKD.
Marta B. Lopes, Roberta Coletti, Flore Duranton, Griet Glorieux, Mayra Alejandra Jaimes Campos, Julie Klein, Matthias Ley, Paul Perco, Alexia Sampri, Aviad Tur‐Sinai   +9 more
wiley   +1 more source