Extracellular Vesicles in Nonalcoholic Fatty Liver Disease: Mechanisms and Therapeutic Opportunities
The role of extracellular vesicles (EVs) in the progression of nonalcoholic fatty liver disease (NAFLD). Donor cells release EVs containing various molecules such as cholesterol, ceramide, sphingomyelin, miRNA, DNA, proteins, and lipids. These EVs are taken up by multiple recipient cells including Kupffer cells, adipocytes, β cells, adipose tissue ...
Yunsheng Dong +12 more
wiley +1 more source
Perspectives on Clinical Biomarkers Based on the Pathophysiology of Arrhythmias
Overview of atrial fibrillation and biomarkers. Biomarkers for atrial fibrillation can be broadly divided into factors causing atrial fibrillation and factors resulting from atrial fibrillation. Nucleic acids and extracellular vesicles released into the extracellular space mediate communication between cells and tissues and are deeply involved in the ...
Tomoya Hara, Masataka Sata
wiley +1 more source
THE EFFECT OF MESENCHYMAL STEM CELL DERIVED MICROVESICLES IN REPAIR OF FEMORAL CHONDRAL DEFECTS IN DOGS [PDF]
Dina Sabry +7 more
openalex +1 more source
Microvesicle-Mediated Tissue Regeneration Mitigates the Effects of Cellular Ageing [PDF]
Nikolaos Panagiotou +6 more
openalex +1 more source
Modular nanosensing platforms utilize nanomaterials and functionalized interfaces to amplify trace different pathogens (like tuberculosis) antigen capture, suppress matrix interference, and enable multiplex detection. Their portability and cost‐effectiveness support rapid screening in resource‐limited settings and real‐time monitoring, advancing high ...
Mei Li +6 more
wiley +1 more source
Fibroblast growth factor-6 enhances CDK2 and MAKT expression in microvesicles derived from human stem cells extracted from exfoliated deciduous teeth [PDF]
Ahmed Othman, Rabab Mubarak, Dina Sabry
openalex +1 more source
Antibody Polyreactivity: A Challenger of Immune Paradigms
This review article discusses the definition and functions of polyreactive antibodies, as well as their physiological roles. It also presents the concept of polyreactivity as a challenger of immunological dogmas. ABSTRACT Polyreactivity refers to the ability of antibodies to bind multiple unrelated antigens, encompassing polyspecificity and promiscuity.
Anastas D. Pashov, Jordan D. Dimitrov
wiley +1 more source
This study identifies differentially expressed miRNAs in urinary extracellular vesicles and kidney biopsies from Gitelman syndrome patients. In particular, hsa‐let‐7d‐3p is the only upregulated miRNA that negatively regulates NEDD4L, a key modulator of sodium transport.
Chao‐Ting Chen +8 more
wiley +1 more source
Restricted diffusion of integral membrane proteins and polyphosphoinositides leads to their depletion in microvesicles released from human erythrocytes [PDF]
Carla Hagelberg, David Allan
openalex +1 more source
Report on the 2nd MObility for Vesicle research in Europe (MOVE) symposium—2024
The 2nd MObility for Vesicle research in Europe (MOVE) Symposium in Belgrade brought over 280 attendees from 28 countries to advance extracellular vesicle (EV) research. Featuring keynotes, presentations, and industry sessions, it covered EV biogenesis, biomarkers, therapies, and manufacturing.
Dorival Mendes Rodrigues‐Junior +5 more
wiley +1 more source

