Increasing Cell Sorting Recovery Using the Simple “Three‐Puddle Method”
ABSTRACT Recovery is a key performance parameter in cell sorters, a metric that assesses the match between the number of particles reported as sorted by the instrument and the actual number of particles gathered in the collection vessels. Sorting relies on the precise timing of the charging of a droplet containing the particle of interest in a critical
María José Castro Pérez+1 more
wiley +1 more source
Hydrous Carbonatitic Liquids Drive CO2 Recycling From Subducted Marls and Limestones
This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Erwin Schettino, Stefano Poli
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Extracellular vesicles (EVs) contain cell‐derived lipids, proteins and RNAs; however, determining the tissue‐ and cell‐type‐specific EV abundances in body fluids remains a significant hurdle for our understanding of EV biology.
Jannik Hjortshøj Larsen+2 more
doaj +1 more source
Secretagogue-triggered Transfer of Membrane Proteins from Neuroendocrine Secretory Granules to Synaptic-like Microvesicles [PDF]
Jane E. Strasser+3 more
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Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia+2 more
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Microvesicles of leukocyte origin
Microvesicles are a new field of biological research. They are subcellular structures ranging in size from 100 to 1000 nm and found in practically all human biological fluids. Their sources are different cells. Microvesicles have a diverse internal composition and carry a wide spectrum of molecules on their surface, which determines their participation
Kseniya L. Markova+5 more
openaire +2 more sources
Local protein dynamics during microvesicle exocytosis in neuroendocrine cells
Calcium triggered exocytosis is key to many physiological processes, including neurotransmitter and hormone release by neurons and endocrine cells. Dozens of proteins regulate exocytosis, yet the temporal and spatial dynamics of these factors during ...
Agila Somasundaram, Justin W. Taraska
semanticscholar +1 more source
This review provides a detailed description of gene mutations and epigenetic mechanisms in central nervous system (CNS) disease, strategies for gene therapy, challenges for CNS gene therapy and gene‐drug nanocarriers. This review also summarizes the applications of nanogenetic therapy platforms in CNS diseases (brain tumors, neurodegenerative diseases,
Fuming Liang+4 more
wiley +1 more source
Di-Leucine Signals Mediate Targeting of Tyrosinase and Synaptotagmin to Synaptic-like Microvesicles within PC12 Cells [PDF]
Anastasiya D. Blagoveshchenskaya+2 more
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Abstract Liquid biopsy can revolutionize cancer patient management as repeated sampling allows real‐time monitoring of disease progression and response to treatment. The circulating transcriptome represents a rich source of potential cancer biomarkers, including coding and non‐coding RNAs.
Mengqian Li+7 more
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