Results 151 to 160 of about 15,195 (308)

Managing microvesicles or Virchow's vicissitude [PDF]

open access: yesThe Journal of Thoracic and Cardiovascular Surgery, 2022
Hunter B. Moore, Alden H. Harken
openaire   +3 more sources

Autographa californica Multiple Nucleopolyhedrovirus ac75 Is Required for the Nuclear Egress of Nucleocapsids and Intranuclear Microvesicle Formation

open access: yesJournal of Virology, 2017
Autographa californica multiple nucleopolyhedrovirus (AcMNPV) orf75 (ac75) is a highly conserved gene of unknown function. In this study, we constructed an ac75 knockout AcMNPV bacmid and investigated the role of ac75 in the baculovirus life cycle.
An-chen Shi   +6 more
semanticscholar   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

open access: yesSmall, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa   +4 more
wiley   +1 more source

Benchmarking transcriptome deconvolution methods for estimating tissue‐ and cell‐type‐specific extracellular vesicle abundances

open access: yesJournal of Extracellular Vesicles
Extracellular vesicles (EVs) contain cell‐derived lipids, proteins and RNAs; however, determining the tissue‐ and cell‐type‐specific EV abundances in body fluids remains a significant hurdle for our understanding of EV biology.
Jannik Hjortshøj Larsen   +2 more
doaj   +1 more source

Microvesicles of leukocyte origin

open access: yesAnnals of the Russian academy of medical sciences, 2018
Microvesicles are a new field of biological research. They are subcellular structures ranging in size from 100 to 1000 nm and found in practically all human biological fluids. Their sources are different cells. Microvesicles have a diverse internal composition and carry a wide spectrum of molecules on their surface, which determines their participation
Kseniya L. Markova   +5 more
openaire   +2 more sources

Microvesicle removal of anticancer drugs contributes to drug resistance in human pancreatic cancer cells

open access: yesOncoTarget, 2016
High mortality in pancreatic cancer patients is partly due to resistance to chemotherapy. We describe that human pancreatic cancer cells acquire drug resistance by a novel mechanism in which they expel and remove chemotherapeutic drugs from the ...
Vandhana Muralidharan-Chari   +8 more
semanticscholar   +1 more source

Microscope‐Free Analyte Detection Based on Fiber‐Optic Gliding Motility Assays

open access: yesSmall, EarlyView.
Lab‐on‐fiber technology enables rapid, cost‐effective, and in situ analyte detection, addressing critical gaps in point‐of‐care diagnostics. This study presents a microscope‐free biosensor that utilizes motor‐protein‐driven microtubules on optical fibers to detect biomarkers like Creatine Kinase‐MB. By tracking gliding speed changes, it offers a novel,
Henry Carey‐Morgan   +4 more
wiley   +1 more source

Native and Engineered Extracellular Vesicles for the Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome

open access: yesSmall Science, EarlyView.
Both native and engineered extracellular vesicles (EVs) are served as promising therapeutic agents for treating acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). To circumvent the limitations of native EVs, various engineering strategies are adopted.
Zhengyan Gu   +12 more
wiley   +1 more source

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