Synaptic-like microvesicles, synaptic vesicle counterparts in endocrine cells, are involved in a novel regulatory mechanism for the synthesis and secretion of hormones [PDF]
, 2001 Microvesicles in endocrine cells are the morphological and functional equivalent of neuronal synaptic vesicles. Microvesicles accumulate various neurotransmitters through a transmitter-specific vesicular transporter energized by vacuolar H+-ATPase.
Hayashi, Mitsuko +5 more
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Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences [PDF]
, 2011 Leonora Balaj +6 more
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Photochemistry and Photobiology, EarlyView.Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio +4 more
wiley +1 more source
Regulated delivery of molecular cargo to invasive tumour-derived microvesicles [PDF]
, 2015 James Clancy +7 more
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Photochemistry and Photobiology, EarlyView.In this model, ROS generated by UVB result in PAFR agonists acting upon the PAFR resulting in MVP generation release via the enzyme aSMase. In photosensitivity, there are increased ROS, resulting in augmented PAF agonists and increased MVP release. This process can be blocked by aSMase inhibitors.
Risha Annamraju +13 more
wiley +1 more source
Age- and sex-specific differences in blood-borne microvesicles from apparently healthy humans [PDF]
, 2015 Callie M Gustafson +3 more
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Endothelial thrombomodulin—Its role in trauma‐induced coagulopathy
Transfusion, EarlyView.Abstract Background Trauma‐induced coagulopathy (TIC) describes a complex set of coagulation changes affecting severely injured patients. The thrombomodulin‐protein C axis is central to the evolution of TIC. Soluble thrombomodulin (sTM) levels are elevated after injury and predict poor clinical outcomes.
Jeries Abu‐Hanna +7 more
wiley +1 more source
Effect of storage on physical and functional properties of extracellular vesicles derived from neutrophilic granulocytes. [PDF]
, 2015 AIM: To carry out a systematic study on the effect of different storage conditions on the number as well as the physical and functional properties of antibacterial extracellular vesicles (EVs) derived from human neutrophilic granulocytes.
Kittel Ágnes +6 more
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Cranial grafting of stem cell-derived microvesicles improves cognition and reduces neuropathology in the irradiated brain [PDF]
, 2016 Janet E. Baulch +11 more
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Microvesicles released from ectopic endometrial foci as a potential biomarker of endometriosis
, 2022 Magdalena Kajdos +4 more
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