Results 51 to 60 of about 16,274 (290)
CLEC2 and CLEC5A: Pathogenic Host Factors in Acute Viral Infections
Frontiers in Immunology, 2019 The protective roles of endosomal toll-like receptors (TLRs) and cytosolic nucleic acid sensors are well elucidated, but the pathogenic host factors during viral infections remain unclear. Spleen tyrosine kinase (Syk)-coupled C-type lectins (CLECs) CLEC2
Pei-Shan Sung +4 more
doaj +1 more source
A Comparative Proteomic Analysis of Extracellular Vesicles Associated With Lipotoxicity
Frontiers in Cell and Developmental Biology, 2021 Extracellular vesicles (EVs) are emerging mediators of intercellular communication in nonalcoholic steatohepatitis (NASH). Palmitate, a lipotoxic saturated fatty acid, activates hepatocellular endoplasmic reticulum stress, which has been demonstrated to ...
Yasuhiko Nakao +23 more
doaj +1 more source
Acoustic Purification of Extracellular Microvesicles [PDF]
ACS Nano, 2015 Microvesicles (MVs) are an increasingly important source for biomarker discovery and clinical diagnostics. The small size of MVs and their presence in complex biological environment, however, pose technical challenges in sample preparation, particularly when sample volumes are small.
Lee, Kyungheon +3 more
openaire +3 more sources
Chemotherapy treatment of multiple myeloma patients increases circulating levels of endothelial microvesicles [PDF]
, 2016 Correspondenc
Adesanya, M. Adeola +5 more
core +1 more source
The biology of extracellular microvesicles [PDF]
Traffic, 2018 The study of extracellular vesicles (EVs) is a rapidly evolving field, owing in large part to recent advances in the realization of their significant contributions to normal physiology and disease. Once discredited as cell debris, these membrane vesicles have now emerged as mediators of intercellular communication by interaction with target cells, drug
Alanna E. Sedgwick +1 more
openaire +2 more sources
Frontiers in Molecular Biosciences, 2021 Respiratory diseases and their comorbidities, such as cardiovascular disease and muscle atrophy, have been increasing in the world. Extracellular vesicles (EVs), which include exosomes and microvesicles, are released from almost all cell types and play ...
Shota Fujimoto +5 more
doaj +1 more source
Levels of procoagulant microvesicles are elevated after traumatic injury and platelet microvesicles are negatively correlated with mortality [PDF]
, 2014 Background: Microvesicles (MV) have been implicated in the development of thrombotic disease, such as acute respiratory distress syndrome (ARDS) and multiple organ failure (MOF).
Chirono GN +5 more
core +1 more source
Microglial microvesicle secretion and intercellular signaling [PDF]
Frontiers in Physiology, 2012 Microvesicles (MVs) are released from almost all cell brain types into the microenvironment and are emerging as a novel way of cell-to-cell communication. This review focuses on MVs discharged by microglial cells, the brain resident myeloid cells, which comprise ∼10-12% of brain population.
Elena eTurola +8 more
openaire +5 more sources
Impact of Chemotherapy on Extracellular Vesicles: Understanding the Chemo-EVs
Frontiers in Oncology, 2019 Chemotherapy is the standard go-to treatment for cancer besides surgery and radiation. It has recently come to light that the interaction between chemotherapy and the immune system is important in maintaining tumor immunity as well as influencing the ...
Nur' Syahada Ab Razak +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu +21 more
wiley +1 more source