Results 51 to 60 of about 18,155 (253)

A Comparative Proteomic Analysis of Extracellular Vesicles Associated With Lipotoxicity

open access: yesFrontiers in Cell and Developmental Biology, 2021
Extracellular vesicles (EVs) are emerging mediators of intercellular communication in nonalcoholic steatohepatitis (NASH). Palmitate, a lipotoxic saturated fatty acid, activates hepatocellular endoplasmic reticulum stress, which has been demonstrated to ...
Yasuhiko Nakao   +23 more
doaj   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

The Emerging Roles of Extracellular Vesicles As Communication Vehicles within the Tumor Microenvironment and Beyond

open access: yesFrontiers in Endocrinology, 2017
Tumors evolve in complex and dynamic microenvironments that they rely on for sustained growth, invasion, and metastasis. Within this space, tumor cells and non-malignant cells are in frequent communication.
Ryan Sullivan   +10 more
doaj   +1 more source

Microvesicle-Mediated Delivery of Minicircle DNA Results in Effective Gene-Directed Enzyme Prodrug Cancer Therapy

open access: yesMolecular Cancer Therapeutics, 2019
An emerging approach for cancer treatment employs the use of extracellular vesicles, specifically exosomes and microvesicles, as delivery vehicles. We previously demonstrated that microvesicles can functionally deliver plasmid DNA to cells and showed ...
M. Kanada   +15 more
semanticscholar   +1 more source

Bibliometric profile of neurogenic bladder in the literature: a 20-year bibliometric analysis

open access: yesNeural Regeneration Research, 2015
Neurogenic bladder is a dysfunction of the lower urinary tract caused by nervous system disorder. We investigated the trends in publication of articles under the topic "neurogenic bladder" using bibliometric analysis.
Yuan Gao   +7 more
doaj   +1 more source

Sorting Mechanisms for MicroRNAs into Extracellular Vesicles and Their Associated Diseases

open access: yesCells, 2020
Extracellular vesicles (EV) are secretory membranous elements used by cells to transport proteins, lipids, mRNAs, and microRNAs (miRNAs). While their existence has been known for many years, only recently has research begun to identify their function in ...
Michael Groot, Heedoo Lee
doaj   +1 more source

Intercellular Communication by Vascular Endothelial Cell-Derived Extracellular Vesicles and Their MicroRNAs in Respiratory Diseases

open access: yesFrontiers in Molecular Biosciences, 2021
Respiratory diseases and their comorbidities, such as cardiovascular disease and muscle atrophy, have been increasing in the world. Extracellular vesicles (EVs), which include exosomes and microvesicles, are released from almost all cell types and play ...
Shota Fujimoto   +5 more
doaj   +1 more source

Microvesicle Proteomic Profiling of Uterine Liquid Biopsy for Ovarian Cancer Early Detection*

open access: yesMolecular & Cellular Proteomics, 2019
High-grade ovarian cancer accounts for higher mortality rates because of ineffective biomarkers for early diagnosis. Deep proteome profiling of the microvesicles from a total of 187 liquid biopsies of Utero-tubal Lavage, combined with support vector ...
G. Barnabas   +23 more
semanticscholar   +1 more source

Acupuncture and vitamin B12 injection for Bell′s palsy: no high-quality evidence exists

open access: yesNeural Regeneration Research, 2015
OBJECTIVE: To assess the efficacy of acupuncture combined with vitamin B 12 acupoint injection versus acupuncture alone to reduce incomplete recovery in patients with Bell′s palsy.
Li-li Wang   +4 more
doaj   +1 more source

Extracellular Vesicle: An Emerging Mediator of Intercellular Crosstalk in Lung Inflammation and Injury

open access: yesFrontiers in Immunology, 2018
Inflammatory lung responses are one of the characterized features in the pathogenesis of many lung diseases, including acute respiratory distress syndrome (ARDS) and chronic obstructive pulmonary disease (COPD).
Heedoo Lee   +4 more
doaj   +1 more source

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