Results 31 to 40 of about 1,559 (152)
International Journal of Molecular Sciences, 2022 Glioblastoma (GB) is the most aggressive and recurrent form of brain cancer in adults. We hypothesized that the identification of biomarkers such as certain microRNAs (miRNAs) and the circulating microvesicles (MVs) that transport them could be key to establishing GB progression, recurrence and therapeutic response.
Natalia Simionescu +7 more
openaire +2 more sources
Biology and biogenesis of shed microvesicles [PDF]
Small GTPases, 2016 The ability of cells to transmit bioactive molecules to recipient cells and the extracellular environment is a fundamental requirement for both normal physiology and disease pathogenesis. It has traditionally been thought that soluble factors released from cells were responsible for this cellular signaling but recent research has revealed a fundamental
Tricarico, Christopher +2 more
openaire +2 more sources
Red Blood Cell Homeostasis: Mechanisms and Effects of Microvesicle Generation in Health and Disease [PDF]
, 2018 Red blood cells (RBCs) generate microvesicles to remove damaged cell constituents such as oxidized hemoglobin and damaged membrane constituents, and thereby prolong their lifespan.
Joames K. F. Leal +5 more
core +1 more source
Neural Regeneration Research, 2015 Ginsenoside Rg1 is the major pharmacologically active component of ginseng, and is reported to have various therapeutic actions. To determine whether it induces the differentiation of neural stem cells, and whether neural stem cell transplantation after ...
Ying-bo Li +4 more
doaj +1 more source
Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy [PDF]
, 2017 Microvesicle (MV) release from tumour cells influences drug retention, contributing to cancer drug resistance. Strategically regulating MV release may increase drug retention within cancer cells and allow for lower doses of chemotherapeutic drugs.
Uchini Kosgodage +14 more
core +1 more source
Frontiers in Aging Neuroscience, 2021 IntroductionIn Alzheimer’s disease, the severity of symptoms is linked to a loss of synaptic density and the spread of pathologically hyperphosphorylated tau.
Janine Utz +9 more
doaj +1 more source
Changes of resting cerebral activities in subacute ischemic stroke patients
Neural Regeneration Research, 2015 This study aimed to detect the difference in resting cerebral activities between ischemic stroke patients and healthy participants, define the abnormal site, and provide new evidence for pathological mechanisms, clinical diagnosis, prognosis prediction ...
Ping Wu +8 more
doaj +1 more source
Endothelial cells release microvesicles that harbour multivesicular bodies and secrete exosomes
Journal of Extracellular Biology, 2023 Extracellular vesicles (EVs) released by endothelial cells support vascular homeostasis. To better understand endothelial cell EV biogenesis, we examined cultured human umbilical vein endothelial cells (HUVECs) prepared by rapid freezing, freeze ...
Jennifer D. Petersen +4 more
doaj +1 more source
Extracellular Vesicle MicroRNA Transfer in Lung Diseases
Frontiers in Physiology, 2017 MicroRNAs (miRNAs) are single-stranded, small non-coding RNAs that ate involved in the transcriptional and post-transcriptional regulation of gene expression.
Jie Chen, Chengping Hu, Pinhua Pan
doaj +1 more source
Biodistribution of extracellular vesicles following administration into animals: A systematic review
Journal of Extracellular Vesicles, 2021 In recent years, attention has turned to examining the biodistribution of EVs in recipient animals to bridge between knowledge of EV function in vitro and in vivo. We undertook a systematic review of the literature to summarize the biodistribution of EVs
Matthew Kang +3 more
doaj +1 more source