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The ins and outs of microvesicles [PDF]
FASEB BioAdvances, 2021 AbstractMicrovesicles are a heterogeneous group of membrane‐enclosed vesicles that are released from cells into the extracellular space by the outward budding and pinching of the plasma membrane. These vesicles are loaded with multiple selectively sorted proteins and nucleic acids.
James W. Clancy +2 more
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Microvesicles and Viral Infection [PDF]
Journal of Virology, 2011 ABSTRACTCells secrete various membrane-enclosed microvesicles from their cell surface (shedding microvesicles) and from internal, endosome-derived membranes (exosomes). Intriguingly, these vesicles have many characteristics in common with enveloped viruses, including biophysical properties, biogenesis, and uptake by cells. Recent discoveries describing
David G, Meckes, Nancy, Raab-Traub
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Neutrophil microvesicles and their role in disease [PDF]
The International Journal of Biochemistry & Cell Biology, 2021 Microvesicles are formed through shedding from the plasma membrane, a process shared by almost all human cells. Microvesicles are highly abundant and have been detected in blood, urine, cerebrospinal fluid, and saliva. They contain a library of cargo derived from their parental cell during formation, including proteases, micro-RNAs and lipids and ...
Reece Dow, Victoria Ridger
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The biology of extracellular microvesicles [PDF]
Traffic, 2018 The study of extracellular vesicles (EVs) is a rapidly evolving field, owing in large part to recent advances in the realization of their significant contributions to normal physiology and disease. Once discredited as cell debris, these membrane vesicles have now emerged as mediators of intercellular communication by interaction with target cells, drug
Alanna E. Sedgwick +1 more
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Journal of Diabetes Research, 2017 Aims. To investigate how circulating microvesicle phenotypes correlate with insulin sensitivity, body composition, plasma lipids, and hepatic fat accumulation.
Jaco Botha +6 more
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Urinary Microvesicle-Bound Uromodulin: A Potential Molecular Biomarker in Diabetic Kidney Disease
Journal of Diabetes Research, 2017 This study was designed to investigate the changes of urinary microvesicle-bound uromodulin and total urinary uromodulin levels in human urine and the correlations with the severity of diabetic kidney disease (DKD).
Neng-jun Lou +6 more
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Frontiers in Cellular Neuroscience, 2021 Brain microvascular endothelial cells (BMECs) are a major component of the blood-brain barrier that maintains brain homeostasis. Preserving and restoring the normal biological functions of BMECs can reverse or reduce brain injury.
Wen Zeng +4 more
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Current Opinion in Endocrinology, Diabetes & Obesity, 2012 Microvesicles (also known as microparticles) are small membranous structures that are released from platelets and cells upon activation or during apoptosis. Microvesicles have been found in blood, urine, synovial fluid, extracellular spaces of solid organs, atherosclerotic plaques, tumors, and elsewhere.
Ming-Lin, Liu, Kevin Jon, Williams
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Extracellular Vesicles and Their Convergence with Viral Pathways
Advances in Virology, 2012 Extracellular vesicles (microvesicles), such as exosomes and shed microvesicles, contain a variety of molecules including proteins, lipids, and nucleic acids.
Thomas Wurdinger +5 more
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Proteomes, 2023 In recent decades, the role played by extracellular vesicles in physiological and pathological processes has attracted attention. Extracellular vesicles are released by different types of cells and carry molecules that could become biomarkers for the ...
Dianny Elizabeth Jimenez +8 more
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