Results 21 to 30 of about 8,491 (234)

Intercellular Communication by Vascular Endothelial Cell-Derived Extracellular Vesicles and Their MicroRNAs in Respiratory Diseases

open access: yesFrontiers in Molecular Biosciences, 2021
Respiratory diseases and their comorbidities, such as cardiovascular disease and muscle atrophy, have been increasing in the world. Extracellular vesicles (EVs), which include exosomes and microvesicles, are released from almost all cell types and play ...
Shota Fujimoto   +5 more
doaj   +1 more source

Encephalic hemodynamic phases in subarachnoid hemorrhage: how to improve the protective effect in patient prognoses

open access: yesNeural Regeneration Research, 2015
Subarachnoid hemorrhage is frequently associated with poor prognoses. Three different hemodynamic phases were identified during subarachnoid hemorrhage: oligemia, hyperemia, and vasospasm. Each phase is associated with brain metabolic changes.
Marcelo de Lima Oliveira   +5 more
doaj   +1 more source

Glycan Node Analysis of Plasma-Derived Extracellular Vesicles

open access: yesCells, 2020
Blood plasma is a readily accessible source of extracellular vesicles (EVs), i.e., cell-secreted nanosized carriers that contain various biomolecules, including glycans.
Sierra A. Walker   +6 more
doaj   +1 more source

Bacterial membrane vesicles and phages in blood after consumption of Lacticaseibacillus rhamnosus JB-1

open access: yesGut Microbes, 2021
Gut microbiota have myriad roles in host physiology, development, and immunity. Though confined to the intestinal lumen by the epithelia, microbes influence distal systems via poorly characterized mechanisms.
Kevin Champagne-Jorgensen   +5 more
doaj   +1 more source

Microvesicles as Mediators of Tissue Regeneration [PDF]

open access: yesTranslational Research, 2014
The use of stem cells in the treatment of various diseases and injuries has received increasing interest during the past decade. Injected stem cells, such as mesenchymal stem cells, stimulate tissue repair largely through the secretion of soluble factors that regulate various processes of tissue regeneration, including inflammatory responses, apoptosis,
Keith, Sabin, Nobuaki, Kikyo
openaire   +2 more sources

Hepatocytes release ceramide-enriched pro-inflammatory extracellular vesicles in an IRE1α-dependent manner[S]

open access: yesJournal of Lipid Research, 2016
Nonalcoholic steatohepatitis (NASH) is a lipotoxic disease wherein activation of endoplasmic reticulum (ER) stress response and macrophage-mediated hepatic inflammation are key pathogenic features.
Eiji Kakazu   +3 more
doaj   +1 more source

Biology and biogenesis of shed microvesicles [PDF]

open access: yesSmall GTPases, 2016
The ability of cells to transmit bioactive molecules to recipient cells and the extracellular environment is a fundamental requirement for both normal physiology and disease pathogenesis. It has traditionally been thought that soluble factors released from cells were responsible for this cellular signaling but recent research has revealed a fundamental
Tricarico, Christopher   +2 more
openaire   +2 more sources

Neuroprotective effects of ginsenoside Rg1-induced neural stem cell transplantation on hypoxic-ischemic encephalopathy

open access: yesNeural Regeneration Research, 2015
Ginsenoside Rg1 is the major pharmacologically active component of ginseng, and is reported to have various therapeutic actions. To determine whether it induces the differentiation of neural stem cells, and whether neural stem cell transplantation after ...
Ying-bo Li   +4 more
doaj   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

Cerebrospinal Fluid of Patients With Alzheimer’s Disease Contains Increased Percentages of Synaptophysin-Bearing Microvesicles

open access: yesFrontiers in Aging Neuroscience, 2021
IntroductionIn Alzheimer’s disease, the severity of symptoms is linked to a loss of synaptic density and the spread of pathologically hyperphosphorylated tau.
Janine Utz   +9 more
doaj   +1 more source

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