Results 61 to 70 of about 15,195 (308)

Chloramidine/Bisindolylmaleimide-I-Mediated Inhibition of Exosome and Microvesicle Release and Enhanced Efficacy of Cancer Chemotherapy

open access: yesInternational Journal of Molecular Sciences, 2017
Microvesicle (MV) release from tumour cells influences drug retention, contributing to cancer drug resistance. Strategically regulating MV release may increase drug retention within cancer cells and allow for lower doses of chemotherapeutic drugs.
Uchini S. Kosgodage   +4 more
semanticscholar   +1 more source

Recent developments in biosensing methods for extracellular vesicle protein characterization

open access: yesWIREs Nanomedicine and Nanobiotechnology, Volume 15, Issue 1, January/February 2023., 2023
Various biosensing principles may serve for the detection and characterisation of extracellular vesicles. Herein, the key platform are systematically reviewed, with a focus on the most recent and fundamental developments. Abstract Research into extracellular vesicles (EVs) has grown significantly over the last few decades with EVs being widely regarded
Jugal Suthar   +4 more
wiley   +1 more source

Changes of resting cerebral activities in subacute ischemic stroke patients

open access: yesNeural Regeneration Research, 2015
This study aimed to detect the difference in resting cerebral activities between ischemic stroke patients and healthy participants, define the abnormal site, and provide new evidence for pathological mechanisms, clinical diagnosis, prognosis prediction ...
Ping Wu   +8 more
doaj   +1 more source

Attack of the microvesicles

open access: yesThe Journal of Cell Biology, 2002
![Graphic][1] Melanoma cells can attack using microvesicles loaded with FasL (red). Fais/RUPMelanoma cells send out microvesicles loaded with Fas ligand (FasL) to kill their would-be assassins, according to Stefano Fais (Istituto Superiore di Sanita, Rome, Italy), Licia Rivoltini (
openaire   +2 more sources

Microvesicles : What's Plasma Made of? [PDF]

open access: yesBiophysical Journal, 2014
Microvesicles (MVs) are cell-derived membrane fragments which are present in plasma and other body fluids. In plasma, MVs participate in physiological processes of hemostasis and inflammation. MVs contain cell-specific molecules and are present at elevated levels in various diseases, which has raised the hypothesis of their potential application as ...
Sisareuth Tan   +4 more
openaire   +2 more sources

von Willebrand factor enhances microvesicle-induced vascular leakage and coagulopathy in mice with traumatic brain injury.

open access: yesBlood, 2018
von Willebrand factor (VWF) is an adhesive ligand, and its activity is proteolytically regulated by the metalloprotease ADAMTS-13 (a disintegrin and metalloprotease with thrombospondin type 1 repeat 13).
Yingang Wu   +15 more
semanticscholar   +1 more source

Immunoregulatory Effects of Stem Cell-Derived Extracellular Vesicles on Immune Cells

open access: yesFrontiers in Immunology, 2020
Recent investigations on the regulatory action of extracellular vesicles (EVs) on immune cells in vitro and in vivo have sparked interest on the subject.
Min Xie   +6 more
doaj   +1 more source

Elevated Levels of Procoagulant Microvesicles and Tissue-Factor Bearing Microvesicles in Malaria Patients

open access: yesInternational Journal of General Medicine, 2023
Procoagulant microvesicles (MVs) are submicron membrane fragments released from activated cells and cells undergoing apoptosis. The procoagulant activity of MVs is enhanced in the presence of tissue factor (TF). MVs and TF are active mediators that induce pro-inflammatory response and prothrombotic tendency and have been linked to the severity of ...
Aymen M Madkhali   +9 more
openaire   +4 more sources

Signed, sealed, delivered: microenvironmental modulation of extracellular vesicle-dependent immunoregulation in the lung

open access: yesFrontiers in Cell and Developmental Biology, 2016
Unconventional secretion and subsequent uptake of molecular cargo via extracellular vesicles (EVs) is an important mechanism by which cells can exert paracrine effects.
Daniel J Schneider   +3 more
doaj   +1 more source

Microvesicle Tissue Factor Procoagulant Activity Is Elevated and Correlated With Disease Severity in Patients With Cirrhosis. [PDF]

open access: yesLiver Int
ABSTRACT Background and Aims Tissue factor‐expressing microvesicles (MV‐TF) have been found to correlate with thrombotic complications in various diseases. Simultaneously, there is expanding research regarding the effect of the coagulation cascade on liver fibrosis progression.
Protopapas AA   +7 more
europepmc   +2 more sources

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