Results 61 to 70 of about 15,493 (301)
ARRDC1 as a mediator of microvesicle budding [PDF]
Proceedings of the National Academy of Sciences, 2012 Eukaryotic cells critically depend on the formation, budding, and scission of membrane-bounded vesicles for many key processes: internalization of cell surface receptors, delivery of cargo proteins to multivesicular bodies (MVBs) and lysosomes for degradation, transport of newly synthesized proteins between intracellular organelles and their delivery ...
Lillian S. Kuo, Eric O. Freed
openaire +2 more sources
International Journal of General Medicine, 2023 Procoagulant microvesicles (MVs) are submicron membrane fragments released from activated cells and cells undergoing apoptosis. The procoagulant activity of MVs is enhanced in the presence of tissue factor (TF). MVs and TF are active mediators that induce pro-inflammatory response and prothrombotic tendency and have been linked to the severity of ...
Aymen M Madkhali +9 more
openaire +4 more sources
Frontiers in Cell and Developmental Biology, 2016 Unconventional secretion and subsequent uptake of molecular cargo via extracellular vesicles (EVs) is an important mechanism by which cells can exert paracrine effects.
Daniel J Schneider +3 more
doaj +1 more source
International Journal of Molecular Sciences, 2017 Microvesicle (MV) release from tumour cells influences drug retention, contributing to cancer drug resistance. Strategically regulating MV release may increase drug retention within cancer cells and allow for lower doses of chemotherapeutic drugs.
Uchini S. Kosgodage +4 more
semanticscholar +1 more source
Possible role of human ribonuclease dicer in the regulation of R loops
FEBS Open Bio, EarlyView.R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik +2 more
wiley +1 more source
Extracellular Vesicle MicroRNA Transfer in Lung Diseases
Frontiers in Physiology, 2017 MicroRNAs (miRNAs) are single-stranded, small non-coding RNAs that ate involved in the transcriptional and post-transcriptional regulation of gene expression.
Jie Chen, Chengping Hu, Pinhua Pan
doaj +1 more source
Effect of storage on physical and functional properties of extracellular vesicles derived from neutrophilic granulocytes [PDF]
Journal of Extracellular Vesicles, 2014 Aim: To carry out a systematic study on the effect of different storage conditions on the number as well as the physical and functional properties of antibacterial extracellular vesicles (EVs) derived from human neutrophilic granulocytes.
Ákos M. Lőrincz +6 more
doaj +1 more source
Blood, 2018 von Willebrand factor (VWF) is an adhesive ligand, and its activity is proteolytically regulated by the metalloprotease ADAMTS-13 (a disintegrin and metalloprotease with thrombospondin type 1 repeat 13).
Yingang Wu +15 more
semanticscholar +1 more source
Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis
FEBS Open Bio, Volume 15, Issue 7, Page 1068-1078, July 2025.Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu +6 more
wiley +1 more source
Microvesicles : What's Plasma Made of? [PDF]
Biophysical Journal, 2014 Microvesicles (MVs) are cell-derived membrane fragments which are present in plasma and other body fluids. In plasma, MVs participate in physiological processes of hemostasis and inflammation. MVs contain cell-specific molecules and are present at elevated levels in various diseases, which has raised the hypothesis of their potential application as ...
Sisareuth Tan +4 more
openaire +2 more sources