Results 91 to 100 of about 59,785 (337)

Atherosclerotic Conditions Promote the Packaging of Functional MicroRNA-92a-3p Into Endothelial Microvesicles

Circulation Research, 2019
Rationale: Microvesicle-incorporated microRNAs (miRs) are biomarkers and effectors of cardiovascular disease. Whether microvesicle-miR expression is regulated in coronary artery disease (CAD) or not is unknown.
Yangyang Liu, Qian Li, M. Hosen, A. Zietzer, A. Flender, P. Levermann, T. Schmitz, D. Frühwald, P. Goody, G. Nickenig, N. Werner, F. Jansen   +11 more
semanticscholar   +1 more source

Encapsulation of Small Extracellular Vesicles into Selectively Disassemblable Shells of PEGylated Metal‐Phenolic Networks

Advanced Healthcare Materials, EarlyView.
Small extracellular vesicles (sEVs) are encapsulated into protective shells composed of metal‐phenolic networks (MPNs) and secondary poly(ethylene glycol) layers. This surface modification approach enhances the storage stability of sEVs while maintaining their integrity and functionality. The shells can be selectively disassembled under mild conditions.
Chenyu Wang, Ailifeire Fulati, Kenta Kimura, Xianglan Li, Joseph J. Richardson, Mitsuru Naito, Kanjiro Miyata, Takanori Ichiki, Hirotaka Ejima   +8 more
wiley   +1 more source

Oral Protein Therapy for the Future - Transport of Glycolipid-Modified Proteins: Vision or Fiction? [PDF]

, 2010
The reliable and early diagnosis of common complex multifactorial diseases depends on the individual determination of all (or as many as possible) polymorphisms of each susceptibility gene together with amount and type of the corresponding gene products ...
Mueller, Guenter
core   +1 more source

Caveolin-1 selectively regulates microRNA sorting into microvesicles after noxious stimuli

Journal of Experimental Medicine, 2019
Extracellular vesicle (EV)–cargo miRNAs mediate intercellular communications. How cells selectively sort the miRNAs into EVs remains unclear. Lee et al. demonstrate a novel mechanism by which functional miRNAs are selectively sorted into EVs via caveolin-
Heedoo Lee, Chunhua Li, Yang Zhang, Duo Zhang, L. Otterbein, Yang Jin   +5 more
semanticscholar   +1 more source

Effect of microvesicles from Moringa oleifera containing miRNA on proliferation and apoptosis in tumor cell lines

Cell Death Discovery, 2020
Human microvesicles are key mediators of cell–cell communication. Exosomes function as microRNA transporters, playing a crucial role in physiological and pathological processes.
Marina Potestà, Valentina Roglia, Marialaura Fanelli, Elisa Pietrobono, A. Gismondi, S. Vumbaca, Rick Gildas Nguedia Tsangueu, A. Canini, V. Colizzi, S. Grelli, A. Minutolo, C. Montesano   +11 more
semanticscholar   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

Advanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan, Jonathan James Stanley Rickard, Mark Robert Thomas, Pola Goldberg Oppenheimer   +3 more
wiley   +1 more source

Microvesicles and chemokines in tumor microenvironment: mediators of intercellular communications in tumor progression

Molecular Cancer, 2019
Increasing evidence indicates that the ability of cancer cells to convey biological information to recipient cells within the tumor microenvironment (TME) is crucial for tumor progression.
X. Bian, Yu-Tian Xiao, Tianqi Wu, Mengfei Yao, Leilei Du, S. Ren, Jianhua Wang   +6 more
semanticscholar   +1 more source

Sialic Acid Glycobiology Unveils Trypanosoma cruzi Trypomastigote Membrane Physiology. [PDF]

, 2016
Trypanosoma cruzi, the flagellate protozoan agent of Chagas disease or American trypanosomiasis, is unable to synthesize sialic acids de novo. Mucins and trans-sialidase (TS) are substrate and enzyme, respectively, of the glycobiological system that ...
A Acosta-Serrano, A Buschiazzo, A Egner, A Galetovic, Andrés B. Lantos, AS Couto, BB Diaz-Rohrer, Beatriz Araoz, CA Buscaglia, CA Buscaglia, Carlos A. Buscaglia, Carolyn R. Bertozzi, DC Bartholomeu, E Bayer-Santos, EJ Finkelsztein, G Bernabo, Giannina Carlevaro, GM Rocha, GM Rocha, GT Dempsey, H Yu, Hai Yu, HT McMahon, HT McMahon, I Levental, I Urban, IA Oliveira, IC Almeida, IC Almeida, J Folling, J Zimmerberg, JA Prescher, JA Prescher, JC Jewett, JH Lumb, JM Baskin, JM Di Noia, JM Di Noia, Juan Mucci, K Simons, KM Tyler, LM De Pablos, LM Freitas, M Hashimoto, Malcolm J. McConville, Mariano Bossi, María de los Milagros Camara, MdL Camara, ME Giorgi, MF Goncalves, MG Risso, ML Salto, MM Camargo, MS Leguizamón, MV Gudheti, NM Quanquin, NW Andrews, Oscar Campetella, P Ruiz Diaz, Pablo Ruiz Diaz, PN Ulrich, RE Thompson, RM de Lederkremer, RP Muiá, S Niyogi, S Schenkman, S Schenkman, S Schenkman, S Tomlinson, SS Rubin de Celis, T Furuya, TJ Gould, Torrecilhas AC Trocoli, U Frevert, V de Paulo Martins, V Jimenez, VA Campo, Vde P Martins, VL Pereira-Chioccola, W de Souza, W de Souza, WB Huttner, X Xu, Xi Chen   +83 more
core   +5 more sources

Investigation on the Influence of Protein Corona and Platelet Adhesion on Storage Bag Surface on the Platelet Storage Lesion

Advanced Healthcare Materials, EarlyView.
Platelet quality deteriorates during storage due to protein and platelet adhesion to current bag materials. Here, polymer coatings are identified that reduce adhesion and translated them to mini‐storage bags. Platelet quality are not impacted, despite significantly reducing adhesion.
Nicolas Pereyra, Kai Yu, Jason Rogalski, Taylor Olivia Da Silva, Parisa Golesorkhi, Madeleine Goldstein, Dana V. Devine, Jayachandran N. Kizhakkedathu   +7 more
wiley   +1 more source

Microvesicles derived from leukocytes in the peripheral blood of patients with external genital endometriosis

Медицинская иммунология, 2022
Endometriosis is a chronic gynecological disease, which poses a serious problem in terms of diagnosis and treatment. Despite decades of research, there are no specific signs and symptoms and no blood tests to clinically confirm the diagnosis, which makes
M. I. Yarmolinskaya, E. I. Durneva, K. L. Markova, V. A. Mikhailova, S. A. Selkov, D. I. Sokolov   +5 more
doaj   +1 more source