Results 101 to 110 of about 59,785 (337)

Epigenetic reprogramming of muscle progenitors: inspiration for clinical therapies [PDF]

, 2015
In the context of regenerative medicine, based on the potential of stem cells to restore diseased tissues, epigenetics is becoming a pivotal area of interest.
Consalvi, Silvia, Saccone, Valentina, Sandona', Martina   +2 more
core   +4 more sources

Exosomes and microvesicles in normal physiology, pathophysiology, and renal diseases

Pediatric nephrology (Berlin, West), 2017
Extracellular vesicles are cell-derived membrane particles ranging from 30 to 5,000 nm in size, including exosomes, microvesicles, and apoptotic bodies. They are released under physiological conditions, but also upon cellular activation, senescence, and ...
Anne-lie Ståhl, K. Johansson, Maria Mossberg, R. Kahn, D. Karpman   +4 more
semanticscholar   +1 more source

Surface Engineering of Thrombus‐Targeting Nanocarriers for Cardiovascular Diseases: A Short Review

Advanced Materials Interfaces, EarlyView.
This paper systematically introduces surface modification strategies for thrombus‐targeting nanocarriers, highlights the clinical significance of nanocarrier‐based thrombolysis therapies, and prospects the synergy of combing thrombolysis and anti‐inflammatory therapies for enhanced therapeutic effect.
Xinyue Ge, Lei Ding, Wenjun Zhao, Bohan Cui, Xiang Guan, Mingfei Pan, Qingguo Li, Ning Gu   +7 more
wiley   +1 more source

Announcing , the Official Journal of the American Society for Exosomes and Microvesicles

Journal of Circulating Biomarkers, 2013
This editorial article introduces the new scientific journal Exosomes and Microvesicles (EXMV) , the official journal of the American Society for Exosomes and Microvesicles (ASEMV), and describes its editorial line and mission in relation to the role of ...
Stephen J. Gould, Douglas Taylor, Antonio Chiesi, Winston P. Kuo   +3 more
doaj   +1 more source

Plasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets [PDF]

, 2019
© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The International Society for Extracellular Vesicles.
Antwi-Baffour, Samuel, Inal, Jameel, Jorfi, Samireh, Lange, Sigrun, Malibha-Pinchbeck, Memory, Stratton, Dan   +5 more
core   +5 more sources

Erythrocyte-derived microvesicles induce arterial spasms in JAK2V617F myeloproliferative neoplasm

Journal of Clinical Investigation, 2020
Arterial cardiovascular events are the leading cause of death in patients with JAK2V617F myeloproliferative neoplasms (MPNs). However, their mechanisms are poorly understood.
J. Poisson, M. Tanguy, Hortense Davy, F. Camara, Marie-Belle El Mdawar, M. Kheloufi, Tracy Dagher, C. Devue, Juliette Lasselin, A. Plessier, S. Merchant, O. Blanc-Brude, M. Souyri, N. Mougenot, F. Dingli, D. Loew, S. Hatem, C. James, J. Villeval, C. Boulanger, P. Rautou   +20 more
semanticscholar   +1 more source

Emerging Therapeutic Strategies for Hearing Loss

Advanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han, Tian Shen, Weiwei He, Hao Wei, Xiaolong Zhao, Wen Yang, Chuan Bu, Xinghua Tang, Yu Zhao, Jiangang Fan   +9 more
wiley   +1 more source

Microvesicles in disease

, 2014
On activation cells shed vesicles from their surface by the process of ectocytosis. These micro-vesicles or Ectosomes express phosphatidyl-serine (PS) on their surface, which can elicit a range of biological effects from immune-suppression to the activation of the clotting and complement pathways.
openaire   +3 more sources

The role of microvesicles in tissue repair [PDF]

Organogenesis, 2011
Microvesicles (MVs) are released by almost all cells in resting and activated conditions. First described several years ago, it is only recently that their mechanisms of action are being elucidated, and their potential role in health and disease is drawing increasing attention.
Maria Chiara Deregibus, Stefania Bruno, Giovanni Camussi, Ciro Tetta, Valentina Fonsato   +4 more
openaire   +3 more sources

Fibronectin Fibers Progressively Lose Their Tension in Invasive Human Breast Carcinoma while Being Tensed in DCIS and Healthy Breast Tissue

Advanced Science, EarlyView.
Extracellular matrix remodeling is crucial in cancer progression. Using a peptide to probe the tension of ECM fibers, it was found that Fibronectin fibers gradually lose tension as human breast carcinoma progresses, while their tension is maintained in ductal carcinoma in situ (DCIS), the non‐invasive precursor of breast cancer. This loss of tension is
Arnaud Miéville, Charlotte M. Fonta, Cornelia Leo, Lucine Christe, Jörg Goldhahn, Gad Singer, Viola Vogel   +6 more
wiley   +1 more source