Results 111 to 120 of about 59,785 (337)
Host cell invasion by Staphylococcus aureus stimulates the shedding of microvesicles [PDF]
, 2013 During severe sepsis, microvesicles that are positive for tissue factor (TF) are at increased levels within blood and in pulmonary lavage. These microvesicles potentially disperse TF, the major initiator of the coagulation cascade, throughout multiple ...
Bruns, Heather A. +4 more
core +1 more source
Massively parallel sequencing of human urinary exosome/microvesicle RNA reveals a predominance of non-coding RNA. [PDF]
PLoS ONE, 2014 Intact RNA from exosomes/microvesicles (collectively referred to as microvesicles) has sparked much interest as potential biomarkers for the non-invasive analysis of disease.
Kevin C Miranda +8 more
doaj +1 more source
Tumor derived Microvesicles enhance cross-processing ability of clinical grade Dendritic Cells [PDF]
, 2018 Tumor cells release extracellular microvesicles (MVs) in the microenvironment to deliver biological signals to neighbouring cells as well as to cells in distant tissues.
Battisti, Federico +11 more
core +1 more source
An ARF6-Exportin-5 Axis Delivers pre-miRNA Cargo to Tumor Microvesicles.
Nature Cell Biology, 2019 Tumour-derived microvesicles (TMVs) comprise a class of extracellular vesicles released from tumour cells that are now understood to facilitate communication between the tumour and the surrounding microenvironment.
James W. Clancy +3 more
semanticscholar +1 more source
Advanced Science, EarlyView.Eosinophils play a crucial role in the progression of temporomandibular joint osteoarthritis (TMJOA). This study demonstrates that eosinophils, induced by OVA/IL‐5, promote Lumican secretion in the synovium, which binds to Annexin A1 in chondrocytes, inhibiting transforming growth factor β2 and Smad2/3 phosphorylation.
Wenqian Chen +12 more
wiley +1 more source
Microvesicles and intercellular communication in the context of parasitism [PDF]
Frontiers in Cellular and Infection Microbiology, 2013 There is a rapidly growing body of evidence that production of microvesicles (MVs) is a universal feature of cellular life. MVs can incorporate microRNA (miRNA), mRNA, mtDNA, DNA and retrotransposons, camouflage viruses/viral components from immune surveillance, and transfer cargo between cells.
Natasha S. Barteneva +4 more
openaire +4 more sources
Cross talk between adipose tissue and placenta in obese and gestational diabetes mellitus pregnancies via exosomes [PDF]
, 2017 Obesity is an important public health issue worldwide, where it is commonly associated with the development of metabolic disorders, especially insulin resistance (IR).
Agustin Gutierrez, Jaime +11 more
core +2 more sources
Advanced Science, EarlyView.This study reveals that M2‐EVs mitigate periodontitis‐induced bone resorption by modulating neutrophil fate. Single‐cell RNA sequencing identified an Anxa1hi neutrophil subpopulation with pro‐reparative properties. M2‐EVs disrupt neutrophil maturation, promoting this subpopulation through key reprogramming genes (Acvrl1, Fpr2). These findings highlight
Yufei Yao +7 more
wiley +1 more source
Novel Molecular Mechanisms in the Development of Non-Alcoholic Steatohepatitis. [PDF]
, 2016 Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease in adults and children worldwide. NAFLD has become a severe health issue and it can progress towards a more severe form of the disease, the non-alcoholic ...
Feldstein, Ariel E, Povero, Davide
core +2 more sources
Advanced Science, EarlyView.Tunneling nanotubes facilitate the transfer of long‐chain fatty acids, primarily arachidonic acid, from tumor cells to macrophages, leading to lipid accumulation and activation of the PI3K‐Akt pathway. This drives a shift from the anti‐tumor CD5L⁺ phenotype to a pro‐tumor TREM2⁺ phenotype.
Meiru Chen +7 more
wiley +1 more source