Results 171 to 180 of about 63,152 (354)
The FEBS Journal, EarlyView.Here, we report the role of extracellular vesicles (EVs) released from melanoma cells constitutively expressing MHC class II in the regulation of immune cell functions and melanoma metastasis. In particular, we observed an increased localization of HLA‐DRα, CAM receptors, PD‐L1, and STAT3 signaling proteins in the EVs.
Francesca Costantini +4 more
wiley +1 more source
Bacterial Extracellular Vesicles in the Pathogenesis and Treatment of Liver Diseases
Journal of Gastroenterology and Hepatology, EarlyView.Liver diseases are a major global health challenge, with current treatments inadequate. This review highlights the role of bacterial extracellular vesicles in liver inflammation, fibrosis, and metabolism. We also explore these from commensals and probiotics, their protective effects, and discuss research challenges and future therapeutic potential ...
Yakun Li +3 more
wiley +1 more source
Characterization of Membrane-shed Microvesicles from Cytokine-stimulated β-Cells Using Proteomics Strategies [PDF]
, 2012 Giuseppe Palmisano +6 more
openalex +1 more source
Journal of Internal Medicine, EarlyView.Abstract The etiology of Alzheimer's disease (AD) remains under active debate. In this perspective, we explore the hypothesis that a primarily infection‐caused chronic dysregulation and weakening of human innate immunity via the underexpression, degradation, and inactivation of innate immune proteins necessary for direct antimicrobial effects and ...
Annelise E. Barron +3 more
wiley +1 more source
Tumour microvesicles contain retrotransposon elements and amplified oncogene sequences [PDF]
, 2011 Leonora Balaj +6 more
openalex +1 more source
Journal of Periodontal Research, EarlyView.The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag +6 more
wiley +1 more source
Regulated delivery of molecular cargo to invasive tumour-derived microvesicles [PDF]
, 2015 James Clancy +7 more
openalex +1 more source
Photochemistry and Photobiology, EarlyView.Photodynamic therapy (PDT) is a nonscarring treatment modality that is widely used for skin cancers and early squamous precursor lesions. PDT was previously thought to work primarily by killing cancer cells directly (via apoptosis or necrosis). However, more recent work indicates that a significant mechanism for PDT is the stimulation of anti‐cancer ...
Mark P. Ortenzio +4 more
wiley +1 more source
Age- and sex-specific differences in blood-borne microvesicles from apparently healthy humans [PDF]
, 2015 Callie M Gustafson +3 more
openalex +1 more source