Results 181 to 190 of about 59,785 (337)

Chinese herbal medicine‐derived extracellular vesicle‐like particles: Therapeutic potential and future research approaches

Interdisciplinary Medicine, EarlyView.
This article evaluates the therapeutic potential of extracellular vesicle‐like particles derived from Chinese herbal medicine (CHM‐EVLP) for a range of diseases. It underscores the significance of traditional Chinese medicine in the development of innovative formulations.
Ying‐qi Cao, Zheng‐ting Wu, Qi You, Yuan‐yuan Xia, Qing Zhao, Carine de Marcos Lousa, Ke‐wei Zhao   +6 more
wiley   +1 more source

Platelet-derived microvesicles isolated from type-2 diabetes mellitus patients harbour an altered miRNA signature and drive MDA-MB-231 triple-negative breast cancer cell invasion.

PLoS ONE
The underlying causes of breast cancer are diverse, however, there is a striking association between type 2 diabetes and poor patient outcomes. Platelet activation is a common feature of both type 2 diabetes and breast cancer and has been implicated in ...
Anca Tutuianu, Chinedu A Anene, Mikayla Shelton, Valerie Speirs, Donald C Whitelaw, Joanne Thorpe, Wayne Roberts, James R Boyne   +7 more
doaj   +1 more source

Lipid-induced hepatocyte-derived extracellular vesicles regulate hepatic stellate cell via microRNAs targeting PPAR-γ. [PDF]

, 2015
Background&aimsHepatic stellate cells (HSCs) play a key role in liver fibrosis in various chronic liver disorders including nonalcoholic fatty liver disease (NAFLD).
Alisi, Anna, de Araujo Horcel, Lucas, Eguchi, Akiko, Feldstein, Ariel E, Johnson, Casey D, Nobili, Valerio, Panera, Nadia, Papouchado, Bettina G, Pinatel, Eva M, Povero, Davide   +9 more
core  

Follicular Dendritic Cells Carry MHC Class II-Expressing Microvesicles at Their Surface [PDF]

, 2000
Kristin Denzer, Marco van Eijk, Monique J. Kleijmeer, Eva Jakobson, C.H. de Groot, Hans J. Geuze   +5 more
openalex   +1 more source

Recognizing the Health Benefits of Plant‐Sourced Omega‐3 Stearidonic Acid: Exploring Its Complementary Role to Preformed EPA/DHA

Lipids, EarlyView.
ABSTRACT Very‐long chain (VLC) omega‐3 polyunsaturated fatty acids (PUFAs) like eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA) are crucial for optimal development, healthy aging, and disease management. Traditionally sourced from fatty fish, these omega‐3 PUFAs face sustainability challenges, prompting increased exploration of plant‐based ...
Ella J. Baker, Greg Cumberford, Patrick Hanaway   +2 more
wiley   +1 more source

Rab4 Regulates Formation of Synaptic-like Microvesicles from Early Endosomes in PC12 Cells [PDF]

, 2001
Heidi de Wit, Yael Lichtenstein, Regis B. Kelly, Hans J. Geuze, Judith Klumperman, Peter van der Sluijs   +5 more
openalex   +1 more source

Microfluidic Systems in Cancer Diagnosis: Advancing Exosome and CTC Detection From Laboratory Research to Clinical Application

Nano Select, EarlyView.
Detection of cancer through the identification of EV markers and CTCs using microfluidic systems is rapidly advancing. These markers are typically identified from liquid biopsy samples, which offer a highly favorable alternative to traditional biopsy methods due to their non‐invasive nature.
Bahareh Valinezhad Saghezi, Kamran Mansouri, Rahman Hallaj   +2 more
wiley   +1 more source

Mitochondrial transfer as a novel therapeutic approach in ischemic stroke treatment: Current challenges and future perspectives

Neuroprotection, EarlyView.
Cerebral ischemia is a serious neurological disease that mainly leads to pathological changes such as mitochondrial dysfunction, oxidative stress and iron death. Mitochondria play a key role in the regulation of cellular energy metabolism and oxidative stress, and their damage can lead to mitochondrial damage, reduced adenosine triphosphate production,
Shuchen Meng, Min Bai, Changsheng Ma, Bo Han, Mengyuan Duan, Liying Zhang, Jinfen Guo, Changku Shi, Ke Li, Maotao He   +9 more
wiley   +1 more source

Microvesicles in platelet concentrates for transfusion [PDF]

, 2000
The key objective of this study was to examine whether leucocyte depletion generated or removed platelet-derived microvesicles in platelet concentrates for transfusion. Three in-process leucocyte removal filters for pooled buffy coat derived platelet concentrates, i. e.
openaire   +2 more sources

Ringer's solution but not hydroxyethyl starch or modified fluid gelatin enhances platelet microvesicle formation in a porcine model of septic shock † [PDF]

, 2004
Tobias Schuerholz, Robert Sümpelmann, S. Piepenbrock, M. Leuwer, Gernot Marx   +4 more
openalex   +1 more source