Microvesicles Transfer Mitochondria and Increase Mitochondrial Function in Brain Endothelial Cells
bioRxiv, 2021 We have demonstrated, for the first time that microvesicles, a sub-type of extracellular vesicles (EVs) derived from hCMEC/D3: a human brain endothelial cell (BEC) line transfer polarized mitochondria to recipient BECs in culture and to neurons in mice ...
A. D'Souza +15 more
semanticscholar +1 more source
Simple method for sub-diffraction resolution imaging of cellular structures on standard confocal microscopes by three-photon absorption of quantum dots [PDF]
, 2013 This study describes a simple technique that improves a recently developed 3D sub-diffraction imaging method based on three-photon absorption of commercially available quantum dots.
A Franceschetti +28 more
core +12 more sources
International Journal of Molecular Sciences, 2022 Glioblastoma (GB) is the most aggressive and recurrent form of brain cancer in adults. We hypothesized that the identification of biomarkers such as certain microRNAs (miRNAs) and the circulating microvesicles (MVs) that transport them could be key to establishing GB progression, recurrence and therapeutic response.
Natalia Simionescu +7 more
openaire +2 more sources
Microvesicles and Viral Infection [PDF]
Journal of Virology, 2011 ABSTRACTCells secrete various membrane-enclosed microvesicles from their cell surface (shedding microvesicles) and from internal, endosome-derived membranes (exosomes). Intriguingly, these vesicles have many characteristics in common with enveloped viruses, including biophysical properties, biogenesis, and uptake by cells. Recent discoveries describing
David G, Meckes, Nancy, Raab-Traub
openaire +2 more sources
Salivary apoptotic microvesicles as biomarkers for prognostic non-healing oral ulcers and oral cancer: a cross-sectional study. [PDF]
Sci RepZhao J, Dong Y, Shi S, Yu H, Tan L.
europepmc +3 more sources
Circulating Microvesicles Are Elevated Acutely following Major Burns Injury and Associated with Clinical Severity. [PDF]
PLoS ONE, 2016 Microvesicles are cell-derived signaling particles emerging as important mediators and biomarkers of systemic inflammation, but their production in severe burn injury patients has not been described.
Kieran P O'Dea +6 more
doaj +1 more source
Plant-Derived Nano and Microvesicles for Human Health and Therapeutic Potential in Nanomedicine
Pharmaceutics, 2021 Plants produce different types of nano and micro-sized vesicles. Observed for the first time in the 60s, plant nano and microvesicles (PDVs) and their biological role have been inexplicably under investigated for a long time.
M. Alfieri, A. Leone, A. Ambrosone
semanticscholar +1 more source
Transfer of microRNAs by embryonic stem cell microvesicles. [PDF]
PLoS ONE, 2009 Microvesicles are plasma membrane-derived vesicles released into the extracellular environment by a variety of cell types. Originally characterized from platelets, microvesicles are a normal constituent of human plasma, where they play an important role ...
Alex Yuan +6 more
doaj +1 more source
The biology of extracellular microvesicles [PDF]
Traffic, 2018 The study of extracellular vesicles (EVs) is a rapidly evolving field, owing in large part to recent advances in the realization of their significant contributions to normal physiology and disease. Once discredited as cell debris, these membrane vesicles have now emerged as mediators of intercellular communication by interaction with target cells, drug
Alanna Sedgwick, C. D’Souza-Schorey
semanticscholar +3 more sources
Extracellular microvesicles/exosomes: discovery, disbelief, acceptance, and the future?
Leukemia, 2020 There are concepts in science that need time to overcome initial disbelief before finally arriving at the moment when they are embraced by the research community.
M. Ratajczak, J. Ratajczak
semanticscholar +1 more source