Results 11 to 20 of about 30,919 (203)
The ins and outs of microvesicles [PDF]
FASEB BioAdvances, 2021 Microvesicles are a heterogeneous group of membrane‐enclosed vesicles that are released from cells into the extracellular space by the outward budding and pinching of the plasma membrane.
James W. Clancy +2 more
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Neutrophil microvesicles and their role in disease [PDF]
The International Journal of Biochemistry & Cell Biology, 2021 Microvesicles are formed through shedding from the plasma membrane, a process shared by almost all human cells. Microvesicles are highly abundant and have been detected in blood, urine, cerebrospinal fluid, and saliva. They contain a library of cargo derived from their parental cell during formation, including proteases, micro-RNAs and lipids and ...
Reece Dow, Victoria Ridger
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R(h)oads to microvesicles [PDF]
Small GTPases, 2012 A novel form of cell-to-cell communication involving the formation and shedding of large vesicular structures, called microvesicles (MVs), from the surfaces of highly aggressive forms of human cancer cells has been attracting increasing amounts of attention. This is in large part due to the fact that MVs contain a variety of cargo that is not typically
Marc A. Antonyak +2 more
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Decoding the microvesicle message [PDF]
Nature Reviews Cancer, 2008 Isobel Barry
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The Immunomodulatory Role of Syncytiotrophoblast Microvesicles
PLoS ONE, 2011 Immune adaptation is a critical component of successful pregnancy. Of primary importance is the modification of cytokine production upon immune activation. With the discovery that normal pregnancy itself is a pro-inflammatory state, it was recognised that the classical Th1/Th2 cytokine paradigm, with a shift towards 'type 2' cytokine production ...
Jennifer H. Southcombe +3 more
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Microvesicles and Viral Infection [PDF]
Journal of Virology, 2011 ABSTRACTCells secrete various membrane-enclosed microvesicles from their cell surface (shedding microvesicles) and from internal, endosome-derived membranes (exosomes). Intriguingly, these vesicles have many characteristics in common with enveloped viruses, including biophysical properties, biogenesis, and uptake by cells. Recent discoveries describing
Nancy Raab-Traub, David G. Meckes
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Blood Cell-Derived Microvesicles in Hematological Diseases and beyond
Biomolecules, 2022 Microvesicles or ectosomes represent a major type of extracellular vesicles that are formed by outward budding of the plasma membrane. Typically, they are bigger than exosomes but smaller than apoptotic vesicles, although they may overlap with both in ...
Hara T. Georgatzakou +4 more
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Microvesicles as immune orchestra conductors
Blood, 2008 In this issue of Blood, Sprague and colleagues report that platelet-derived membrane vesicles (PDMVs) orchestrate an immune response sufficient to deliver CD154 signals, which stimulate antigen-specific IgG production and modulate germinal-center formation, by cooperating with responses elucidated by CD4+ T cells.
Mariusz Z. Ratajczak
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Transfer of microRNAs by embryonic stem cell microvesicles. [PDF]
PLoS ONE, 2009 Microvesicles are plasma membrane-derived vesicles released into the extracellular environment by a variety of cell types. Originally characterized from platelets, microvesicles are a normal constituent of human plasma, where they play an important role ...
Alex Yuan +6 more
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The biology of extracellular microvesicles [PDF]
Traffic, 2018 The study of extracellular vesicles (EVs) is a rapidly evolving field, owing in large part to recent advances in the realization of their significant contributions to normal physiology and disease. Once discredited as cell debris, these membrane vesicles have now emerged as mediators of intercellular communication by interaction with target cells, drug
Alanna E. Sedgwick +1 more
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