Results 31 to 40 of about 32,107 (231)

LY86, LRG1 and PDE9A genes overexpression in umbilical cord blood hematopoietic stem progenitor cells by acute myeloid leukemia (M3) microvesicles

open access: yesExperimental Hematology & Oncology, 2019
Background Microvesicles as a new device of cell–cell communication are potentially able to induce some phenotypes and genotypes of an origin cell in a target cell. We evaluate the role of leukemia microvesicles on the leukemia stem cells (LSCs)-specific
Farnaz Razmkhah   +3 more
doaj   +1 more source

Breast cancer exosome-like microvesicles and salivary gland cells interplay alters salivary gland cell-derived exosome-like microvesicles in vitro.

open access: yesPLoS ONE, 2012
Saliva is a useful biofluid for the early detection of disease, but how distal tumors communicate with the oral cavity and create disease-specific salivary biomarkers remains unclear.
Chang S Lau, David T W Wong
doaj   +1 more source

Colorectal cancer cell-derived microvesicles are enriched in cell cycle-related mRNAs that promote proliferation of endothelial cells

open access: yesBMC Genomics, 2009
Background Various cancer cells, including those of colorectal cancer (CRC), release microvesicles (exosomes) into surrounding tissues and peripheral circulation.
Kim Yoon-Keun   +10 more
doaj   +1 more source

Cellular phenotype switching and microvesicles [PDF]

open access: yesAdvanced Drug Delivery Reviews, 2010
Cell phenotype alteration by cell-derived vesicles presents a new aspect for consideration of cell fate. Accumulating data indicates that vesicles from many cells interact with or enter different target cells from other tissues, altering their phenotype toward that of the cell releasing the vesicles.
Peter J, Quesenberry, Jason M, Aliotta
openaire   +2 more sources

The Immunomodulatory Role of Syncytiotrophoblast Microvesicles

open access: yesPLoS ONE, 2011
Immune adaptation is a critical component of successful pregnancy. Of primary importance is the modification of cytokine production upon immune activation. With the discovery that normal pregnancy itself is a pro-inflammatory state, it was recognised that the classical Th1/Th2 cytokine paradigm, with a shift towards 'type 2' cytokine production ...
Southcombe, J   +3 more
openaire   +6 more sources

Circulating Microvesicles in Regenerative Angiogenesis [PDF]

open access: yesCurrent Trends in Biomedical Engineering & Biosciences, 2017
Extracellular microvesicles (EVs) released by different cells have been shown to facilitate the transfer of several pro-angiogenic as well as anti-antigenic factors that can regulate gene expression in endothelial cells. Our recent study has demonstrated that the profiles of cytokines and angiogenic-active factors in EVs are significantly changed in ...
Drożdż, Anna, Stępień, Ewa
openaire   +2 more sources

Therapeutic Extracellular Vesicles from Synovial Fibroblast‐Primed MSCs for Osteoarthritis Treatment

open access: yesAdvanced Healthcare Materials, EarlyView.
EVs derived from the microenvironment of SFs transferred MSCs (miSF‐MSC‐EVs) enhanced the expression of miRNAs that regulate cell migration, cell adhesion, and the TGF‐β signaling pathway, demonstrating superior anti‐inflammatory and cartilage regeneration effects compared to conventional MSC‐EVs.
Seo Jeong Kim   +5 more
wiley   +1 more source

The role of the host—Neutrophil biology

open access: yesPeriodontology 2000, EarlyView., 2023
Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple   +4 more
wiley   +1 more source

In Vivo Monitoring of Thrombo‐Inflammatory Biomarkers via Molecularly Imprinted Polymer‐Integrated Hydrogel Microneedles

open access: yesAdvanced Materials, EarlyView.
A wearable electrochemical microneedle patch integrates Prussian Blue redox transduction with molecularly imprinted polymer recognition for reagent‐free sampling and detection of thrombo‐inflammatory biomarkers in dermal interstitial fluid. The platform tracks thrombin and inflammatory cytokines with sensitive in vitro, ex vivo, and in vivo performance,
Mahmoud Ayman Saleh   +11 more
wiley   +1 more source

Leukemia microvesicles affect healthy hematopoietic stem cells

open access: yesTumor Biology, 2017
Microvesicles are released by different cell types and shuttle mRNAs and microRNAs which have the possibility to transfer genetic information to a target cell and alter its function.
Farnaz Razmkhah   +7 more
doaj   +1 more source

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