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The ins and outs of microvesicles [PDF]
FASEB BioAdvances, 2021 Microvesicles are a heterogeneous group of membrane‐enclosed vesicles that are released from cells into the extracellular space by the outward budding and pinching of the plasma membrane.
James W. Clancy +2 more
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Microvesicles and Viral Infection [PDF]
Journal of Virology, 2011 ABSTRACTCells secrete various membrane-enclosed microvesicles from their cell surface (shedding microvesicles) and from internal, endosome-derived membranes (exosomes). Intriguingly, these vesicles have many characteristics in common with enveloped viruses, including biophysical properties, biogenesis, and uptake by cells. Recent discoveries describing
David G, Meckes, Nancy, Raab-Traub
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Neutrophil microvesicles and their role in disease [PDF]
The International Journal of Biochemistry & Cell Biology, 2021 Microvesicles are formed through shedding from the plasma membrane, a process shared by almost all human cells. Microvesicles are highly abundant and have been detected in blood, urine, cerebrospinal fluid, and saliva. They contain a library of cargo derived from their parental cell during formation, including proteases, micro-RNAs and lipids and ...
Reece Dow, Victoria Ridger
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The biology of extracellular microvesicles [PDF]
Traffic, 2018 The study of extracellular vesicles (EVs) is a rapidly evolving field, owing in large part to recent advances in the realization of their significant contributions to normal physiology and disease. Once discredited as cell debris, these membrane vesicles have now emerged as mediators of intercellular communication by interaction with target cells, drug
Alanna E. Sedgwick +1 more
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Current Opinion in Endocrinology, Diabetes & Obesity, 2012 Microvesicles (also known as microparticles) are small membranous structures that are released from platelets and cells upon activation or during apoptosis. Microvesicles have been found in blood, urine, synovial fluid, extracellular spaces of solid organs, atherosclerotic plaques, tumors, and elsewhere.
Ming-Lin, Liu, Kevin Jon, Williams
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EVALUATION OF MICROVESICLES FORMED BY NATURAL KILLER (NK) CELLS USING FLOW CYTOMETRY
Медицинская иммунология, 2018 As a result of activation and/or apoptosis, the cells can form microvesicles (MV) from 100 nm up to 1000 nm in size. Nowadays, the attention is being increasingly focused on dynamic detection and evaluation of leukocyte-derived microvesicles by their ...
V. A. Mikhailova +5 more
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BMC Cancer, 2017 Background Microvesicles are small vesicles expressing specific antigens from their cells of origin. Elevated levels of microvesicles have been shown to be associated with coagulation disorders as well as with different types of malignancies.
A. Fricke +13 more
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Stem Cells International, 2020 Endothelial progenitor cells (EPCs) and mesenchymal stem/stromal cells (MSCs) are associated with maintaining tissue homeostasis and tissue repair. Both types of cells contribute to tissue regeneration through the secretion of trophic factors (alone or ...
Agnieszka Krawczenko +6 more
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Microvesicles as Mediators of Tissue Regeneration [PDF]
Translational Research, 2014 The use of stem cells in the treatment of various diseases and injuries has received increasing interest during the past decade. Injected stem cells, such as mesenchymal stem cells, stimulate tissue repair largely through the secretion of soluble factors that regulate various processes of tissue regeneration, including inflammatory responses, apoptosis,
Keith, Sabin, Nobuaki, Kikyo
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Detection of microRNA expression in human peripheral blood microvesicles. [PDF]
PLoS ONE, 2008 MicroRNAs (miRNA) are small non-coding RNAs that regulate translation of mRNA and protein. Loss or enhanced expression of miRNAs is associated with several diseases, including cancer.
Melissa Piper Hunter +12 more
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