Results 41 to 50 of about 53,120 (272)

The role of microvesicles as biomarkers in the screening of colorectal neoplasm

Cancer Medicine, 2022
Background Colorectal cancer (CRC) is the second cause of cancer death worldwide. The role of circulating microvesicles as a screening tool is a novel, yet effective approach that warrants prioritised research.
Mohammad M. R. Eddama, Rijan Gurung, Konstantinos Fragkos, Paula Lorgelly, Richard Cohen, Marilena Loizidou, Lucie Clapp   +6 more
doaj   +1 more source

Epigenetic reprogramming of muscle progenitors: inspiration for clinical therapies [PDF]

, 2015
In the context of regenerative medicine, based on the potential of stem cells to restore diseased tissues, epigenetics is becoming a pivotal area of interest.
Consalvi, Silvia, Saccone, Valentina, Sandona', Martina   +2 more
core   +4 more sources

The Ratio of Factor VIIa:Tissue Factor Content within Microvesicles Determines the Differential Influence on Endothelial Cells

TH Open, 2019
Tissue factor (TF)-positive microvesicles from various sources can promote cellular proliferation or alternatively induce apoptosis, but the determining factors are unknown.
Yahya Madkhali, Sophie Featherby, Mary E. Collier, Anthony Maraveyas, John Greenman, Camille Ettelaie   +5 more
doaj   +1 more source

Long-term high fat feeding of rats results in increased numbers of circulating microvesicles with pro-inflammatory effects on endothelial cells [PDF]

, 2015
Obesity and type 2 diabetes lead to dramatically increased risks of atherosclerosis and CHD. Multiple mechanisms converge to promote atherosclerosis by increasing endothelial oxidative stress and up-regulating expression of pro-inflammatory molecules ...
Bastard, C. Lawson, D. K. Andersen, L. F. Heinrich, M. E. Cleasby, Mulcahy, Yan   +6 more
core   +2 more sources

LY86, LRG1 and PDE9A genes overexpression in umbilical cord blood hematopoietic stem progenitor cells by acute myeloid leukemia (M3) microvesicles

Experimental Hematology & Oncology, 2019
Background Microvesicles as a new device of cell–cell communication are potentially able to induce some phenotypes and genotypes of an origin cell in a target cell. We evaluate the role of leukemia microvesicles on the leukemia stem cells (LSCs)-specific
Farnaz Razmkhah, Sorayya Ghasemi, Masoud Soleimani, Sedigheh Amini Kafi-abad   +3 more
doaj   +1 more source

Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells. [PDF]

PLoS ONE, 2012
BACKGROUND: Shedding microvesicles are membrane released vesicles derived directly from the plasma membrane. Exosomes are released membrane vesicles of late endosomal origin that share structural and biochemical characteristics with prostasomes ...
Anders Waldenström, Nina Gennebäck, Urban Hellman, Gunnar Ronquist   +3 more
doaj   +1 more source

Tumor derived Microvesicles enhance cross-processing ability of clinical grade Dendritic Cells [PDF]

, 2018
Tumor cells release extracellular microvesicles (MVs) in the microenvironment to deliver biological signals to neighbouring cells as well as to cells in distant tissues.
Battisti, Federico, Belleudi, Francesca, Claudia De Archangelis,, DI FILIPPO, Alessandra, Dionisi, Marco, Napoletano, Chiara, Nuti, Marianna, RAHIMI KOSHKAKI, Hassan, Rughetti, Aurelia, Ruscito, Ilary, Torrisi, Maria Rosaria, Zizzari, ILARIA GRAZIA   +11 more
core   +1 more source

Breast cancer exosome-like microvesicles and salivary gland cells interplay alters salivary gland cell-derived exosome-like microvesicles in vitro.

PLoS ONE, 2012
Saliva is a useful biofluid for the early detection of disease, but how distal tumors communicate with the oral cavity and create disease-specific salivary biomarkers remains unclear.
Chang S Lau, David T W Wong
doaj   +1 more source

Filamin-A is required for the incorporation of tissue factor into cell-derived microvesicles [PDF]

, 2013
We previously reported that the incorporation of tissue factor (TF) into cell-derived microvesicles (MVs) is regulated by the phosphorylation of the cytoplasmic domain of TF.
Collier, Mary E. W., Ettelaie, Camille, Maraveyas, Anthony   +2 more
core   +1 more source

Thromboinflammatory effects of RBC microvesicles [PDF]

Blood, 2020
In this issue of Blood, Noubouossie et al provide new insights into potential mechanisms for thromboinflammatory complications associated with red blood cell (RBC) transfusions. By using leukoreduced RBC units to isolate RBC microvesicles (RBC-MVs), they document that RBC-MVs activate factor IX (FIX) via 2 distinct pathways: (1) the canonical ...
openaire   +2 more sources