Alteration of Marrow Cell Gene Expression, Protein Production, and Engraftment into Lung by Lung-Derived Microvesicles: A Novel Mechanism for Phenotype Modulation [PDF]
, 2007 Jason M. Aliotta +16 more
openalex +1 more source
Aging Cell, EarlyView.We performed the first integrative multiparametric analysis of plasma circulating cell‐free nucleic acids, including nuclear and mitochondrial DNA, as well as ribosomal, messenger, and micro‐RNAs, in a cohort of 139 healthy individuals. We focused on quantity, integrity, and DNA methylation using assays targeting highly repetitive DNA and highly ...
Nicolas P. Tessier +10 more
wiley +1 more source
Macrophage Efferocytosis as a Therapeutic Strategy in Intervertebral Disc Degeneration
Cell Proliferation, EarlyView.Macrophages, integral to degenerated intervertebral discs, play a critical role in disc degeneration. By performing efferocytosis, they clear apoptotic cells. This article explores the process of efferocytosis, its molecular mechanisms, potential therapeutic implications for intervertebral disc degeneration and future strategies for targeted treatments.
Shijie Chen +9 more
wiley +1 more source
Tumor‐derived microvesicles in sera of patients with head and neck cancer and their role in tumor progression [PDF]
, 2008 Christoph Bergmann +8 more
openalex +1 more source
A review of the equine suspensory ligament: Injury prone yet understudied
Equine Veterinary Journal, EarlyView.Abstract The suspensory ligament (SL) is a key component of the elaborate and highly adapted suspensory apparatus in the horse. In addition to contributing to stabilisation of the metacarpophalangeal joint, the SL has a spring like function to reduce the energetic cost of locomotion.
Deborah J. Guest +2 more
wiley +1 more source
WNT5a export onto extracellular vesicles studied at single‐molecule and single‐vesicle resolution
The FEBS Journal, EarlyView.WNT signaling, which orchestrates tissue development and homeostasis, is mediated by hydrophobic WNT proteins traveling from secreting to receiving cells on various carriers. Here, fusion constructs of fluorescent proteins with WNT5a were developed and functionally validated.
Antonia Schubert +16 more
wiley +1 more source
Extracellular vesicles in multiple myeloma: pathogenesis and therapeutic application
The FEBS Journal, EarlyView.Multiple myeloma is characterised by the clonal proliferation of plasma cells in the bone marrow. Extracellular vesicles (EVs) are a key component of cell‐to‐cell communication within the bone marrow microenvironment, promoting tumour growth, bone remodelling, immune modulation, angiogenesis and therapeutic resistance.
Chloe Wylie +3 more
wiley +1 more source
Трансплантология (Москва)Background. The significance of the problem of treatment of acute pancreatitis is due to an increase in the incidence with an increase in the number of necrotizing forms, accompanied by a high incidence of severe complications and high mortality ...
O. A. Kudelich +4 more
doaj +1 more source
Membrane Microvesicles as Actors in the Establishment of a Favorable Prostatic Tumoral Niche: A Role for Activated Fibroblasts and CX3CL1-CX3CR1 Axis [PDF]
, 2009 Donatello Castellana +6 more
openalex +1 more source