Results 41 to 50 of about 55,239 (279)
Biology and biogenesis of shed microvesicles [PDF]
Small GTPases, 2016 The ability of cells to transmit bioactive molecules to recipient cells and the extracellular environment is a fundamental requirement for both normal physiology and disease pathogenesis. It has traditionally been thought that soluble factors released from cells were responsible for this cellular signaling but recent research has revealed a fundamental
Tricarico, Christopher +2 more
openaire +2 more sources
The role of microvesicles as biomarkers in the screening of colorectal neoplasm
Cancer Medicine, 2022 Background Colorectal cancer (CRC) is the second cause of cancer death worldwide. The role of circulating microvesicles as a screening tool is a novel, yet effective approach that warrants prioritised research.
Mohammad M. R. Eddama +6 more
doaj +1 more source
Cellular phenotype switching and microvesicles [PDF]
Advanced Drug Delivery Reviews, 2010 Cell phenotype alteration by cell-derived vesicles presents a new aspect for consideration of cell fate. Accumulating data indicates that vesicles from many cells interact with or enter different target cells from other tissues, altering their phenotype toward that of the cell releasing the vesicles.
Peter J, Quesenberry, Jason M, Aliotta
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Experimental Hematology & Oncology, 2019 Background Microvesicles as a new device of cell–cell communication are potentially able to induce some phenotypes and genotypes of an origin cell in a target cell. We evaluate the role of leukemia microvesicles on the leukemia stem cells (LSCs)-specific
Farnaz Razmkhah +3 more
doaj +1 more source
Cardiomyocyte microvesicles contain DNA/RNA and convey biological messages to target cells. [PDF]
PLoS ONE, 2012 BACKGROUND: Shedding microvesicles are membrane released vesicles derived directly from the plasma membrane. Exosomes are released membrane vesicles of late endosomal origin that share structural and biochemical characteristics with prostasomes ...
Anders Waldenström +3 more
doaj +1 more source
Plasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets [PDF]
, 2019 © 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The International Society for Extracellular Vesicles.
Antwi-Baffour, Samuel +5 more
core +5 more sources
PLoS ONE, 2012 Saliva is a useful biofluid for the early detection of disease, but how distal tumors communicate with the oral cavity and create disease-specific salivary biomarkers remains unclear.
Chang S Lau, David T W Wong
doaj +1 more source
Long-term high fat feeding of rats results in increased numbers of circulating microvesicles with pro-inflammatory effects on endothelial cells [PDF]
, 2015 Obesity and type 2 diabetes lead to dramatically increased risks of atherosclerosis and CHD. Multiple mechanisms converge to promote atherosclerosis by increasing endothelial oxidative stress and up-regulating expression of pro-inflammatory molecules ...
Bastard +6 more
core +2 more sources
Circulating Microvesicles in Regenerative Angiogenesis [PDF]
Current Trends in Biomedical Engineering & Biosciences, 2017 Extracellular microvesicles (EVs) released by different cells have been shown to facilitate the transfer of several pro-angiogenic as well as anti-antigenic factors that can regulate gene expression in endothelial cells. Our recent study has demonstrated that the profiles of cytokines and angiogenic-active factors in EVs are significantly changed in ...
Drożdż, Anna, Stępień, Ewa
openaire +2 more sources
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source