Results 71 to 80 of about 63,152 (354)

Microvesicles in Cancer: Small Size, Large Potential

International Journal of Molecular Sciences, 2020
Extracellular vesicles (EV) are secreted by all cell types in a tumor and its microenvironment (TME), playing an essential role in intercellular communication and the establishment of a TME favorable for tumor invasion and metastasis.
Kerstin Menck, S. Sivaloganathan, A. Bleckmann, C. Binder   +3 more
semanticscholar   +1 more source

Plasma mEV levels in Ghanain malaria patients with low parasitaemia are higher than those of healthy controls, raising the potential for parasite markers in mEVs as diagnostic targets [PDF]

, 2019
© 2019 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group on behalf of The International Society for Extracellular Vesicles.
Antwi-Baffour, Samuel, Inal, Jameel, Jorfi, Samireh, Lange, Sigrun, Malibha-Pinchbeck, Memory, Stratton, Dan   +5 more
core   +5 more sources

Microvesicles: Novel Biomarkers for Neurological Disorders [PDF]

Frontiers in Physiology, 2012
Microvesicles (MVs) are released by most cell types in physiological conditions, but their number is often increased upon cellular activation or neoplastic transformation. This suggests that their detection may be helpful in pathological conditions to have information on activated cell types and, possibly, on the nature of the activation. This could be
Colombo E, Borgiani B, Verderio C, Furlan R   +3 more
openaire   +4 more sources

Mesenchymal Stem Cell‐Derived Apoptotic Micro‐Vesicles Repaired Sciatic Nerve Defect by Regulating Early Inflammatory Microenvironment and Promoting Angiogenesis

Advanced Healthcare Materials, EarlyView.
HUCMSC‐Apo‐mvs enhance peripheral nerve repair by modulating the inflammatory microenvironment (IME), primarily through coordinated actions on three functional cells. They recruit macrophages and promote their polarization from pro‐inflammatory M1 to anti‐inflammatory M2 phenotypes, increasing secretion of IL‐10 and VEGF.
Haolin Liu, Yiben Ouyang, Bo Wang, Xiaochun Zhang, Yanjun Guan, Ruichao He, Yuhui Cui, Junli Wang, Qianru Yao, Yixiao Tan, Xiwei Peng, Xing Xiong, Sice Wang, Dongdong Li, Haofeng Cheng, Tianqi Su, Xiaoyang Fu, Jinjuan Zhao, Mingqian Yu, Yi Wang, Jiang Peng, Yu Wang   +21 more
wiley   +1 more source

Leukemia microvesicles affect healthy hematopoietic stem cells

Tumor Biology, 2017
Microvesicles are released by different cell types and shuttle mRNAs and microRNAs which have the possibility to transfer genetic information to a target cell and alter its function.
Farnaz Razmkhah, Masoud Soleimani, Davood Mehrabani, Mohammad Hossein Karimi, Sedigheh Amini Kafi-abad, Mani Ramzi, Mahdiyar Iravani Saadi, Javad Kakoui   +7 more
doaj   +1 more source

Atherosclerotic Conditions Promote the Packaging of Functional MicroRNA-92a-3p Into Endothelial Microvesicles

Circulation Research, 2019
Rationale: Microvesicle-incorporated microRNAs (miRs) are biomarkers and effectors of cardiovascular disease. Whether microvesicle-miR expression is regulated in coronary artery disease (CAD) or not is unknown.
Yangyang Liu, Qian Li, M. Hosen, A. Zietzer, A. Flender, P. Levermann, T. Schmitz, D. Frühwald, P. Goody, G. Nickenig, N. Werner, F. Jansen   +11 more
semanticscholar   +1 more source

Cancer-Associated Thrombosis in Cirrhotic Patients with Hepatocellular Carcinoma. [PDF]

, 2018
It is common knowledge that cancer patients are more prone to develop venous thromboembolic complications (VTE). It is therefore not surprising that patients with hepatocellular carcinoma (HCC) present with a significant risk of VTE, with the portal vein
Burra, P, Campello, E, Russo, Fp., Simioni, P, Spiezia, L, Zanetto, A   +5 more
core   +1 more source

Nano‐Engineered Titanium Implants Loaded With Gingival Fibroblasts‐Derived Microvesicles Enhance Early Osseointegration And Soft Tissue Attachment In Vivo

Advanced Healthcare Materials, EarlyView.
Our study showed that human primary gingival fibroblast–derived microvesicles on nano‐engineered titanium implants promote early osseointegration and soft‐tissue attachment in vivo. ABSTRACT Titanium dental implants require both reliable osseointegration and peri‐implant soft tissue seal formation to ensure long‐term success. While osseointegration has
Pingping Han, Chun Liu, Anjana Jayasree, Kamil Sokolowski, Andrew Liaw, Dingbin Liu, Carlos Salomon, Karan Gulati, Ryan SB Lee, Baoxin Huang, Sašo Ivanovski   +10 more
wiley   +1 more source

Effect of microvesicles from Moringa oleifera containing miRNA on proliferation and apoptosis in tumor cell lines

Cell Death Discovery, 2020
Human microvesicles are key mediators of cell–cell communication. Exosomes function as microRNA transporters, playing a crucial role in physiological and pathological processes.
Marina Potestà, Valentina Roglia, Marialaura Fanelli, Elisa Pietrobono, A. Gismondi, S. Vumbaca, Rick Gildas Nguedia Tsangueu, A. Canini, V. Colizzi, S. Grelli, A. Minutolo, C. Montesano   +11 more
semanticscholar   +1 more source

Epithelial cell-derived microvesicles activate macrophages and promote inflammation via microvesicle-containing microRNAs [PDF]

Scientific Reports, 2016
AbstractIntercellular communications between lung epithelial cells and alveolar macrophages play an essential role in host defense against acute lung injury. Hyperoxia-induced oxidative stress is an established model to mimic human lung injury. We show that after hyperoxia-associated oxidative stress, a large amount of extracellular vesicles (EVs) are ...
Heedoo Lee, Duo Zhang, Ziwen Zhu, Charles S. Dela Cruz, Yang Jin   +4 more
openaire   +2 more sources