Results 1 to 10 of about 152,722 (386)

Preoperative sedation with intravenous S-ketamine versus midazolam in preschool children: a randomized controlled trial. [PDF]

BMC Anesthesiol
Liao YQ, Ma J, He Y, Su YW, Xu MZ, Zhang MQ.   +5 more
europepmc   +3 more sources

The effects of Andrographis paniculata (Burm.f.) Nees on the pharmacokinetics and pharmacodynamics of midazolam in healthy volunteers [PDF]

Songklanakarin Journal of Science and Technology (SJST), 2012
Andrographis paniculata (Burm.f.) Nees has been widely used for centuries in Asia for the treatment of common coldand diarrhea. Although it was previously reported to inhibit cytochrome P450 in vitro, the potential to cause herb-druginteraction has been ...
Malinee Wongnawa, Potjanee Soontaro, Wibool Riditid, Payom Wongpoowarak, Suwit Ruengkittisakul   +4 more
doaj   +2 more sources

Efficacy of remimazolam versus midazolam for procedural sedation: post hoc integrated analyses of three phase 3 clinical trials

Endoscopy International Open, 2022
Background and study aims Remimazolam is an ultra-short acting, fast onset/fast offset benzodiazepine for intravenous use in procedural sedation, general anesthesia, and Intensive Care Unit sedation.
Van-Anh Dao, Frank Schippers, Thomas Stöhr   +2 more
doaj   +1 more source

Avoiding the incompatibility of peripheral parenteral nutrition solution and midazolam injection for intravenous sedation

Fujita Medical Journal, 2021
Objectives: We have observed white turbidity when a midazolam injection is administered from a lateral tube during the administration of a peripheral parenteral nutrition (PPN) solution. The aim of the current study was to determine how to avoid compound
Akihiko Futamura, Takashi Higashiguchi, Takeshi Chihara, Yuka Yokota, Yoshinori Itani   +4 more
doaj   +1 more source

Perbedaan Waktu Pulih Sadar Anestesi Umum Sevofluran dengan Premedikasi Midazolam dan tanpa Premedikasi Midazolam

Jurnal Anestesi Perioperatif, 2022
Pemberian premedikasi midazolam memberikan efek sedasi yang panjang sehingga menimbulkan pulih sadar yang lebih lama. Tujuan penelitian ini adalah mengetahui perbedaan waktu pulih sadar anestesi umum sevofluran dengan dan tanpa premedikasi midazolam ...
Purwoko Purwoko, Ardana Tri Arianto, Djoko Tjahyo Nugroho   +2 more
doaj   +1 more source

Inflammation and cardiovascular status impact midazolam pharmacokinetics in critically ill children: An observational, prospective, controlled study

Pharmacology Research & Perspectives, 2022
Altered physiology caused by critical illness may change midazolam pharmacokinetics and thereby result in adverse reactions and outcomes in this vulnerable patient population.
Bikalpa Neupane, Hitesh Pandya, Tej Pandya, Rupert Austin, Neil Spooner, James Rudge, Hussain Mulla   +6 more
doaj   +1 more source

Retrospective Study of Midazolam Protocol for Prehospital Behavioral Emergencies [PDF]

, 2020
Introduction: Agitated patients in the prehospital setting pose challenges for both patient care and emergency medical services (EMS) provider safety. Midazolam is frequently used to control agitation in the emergency department setting; however, limited
Huebinger, Ryan M., Markul, Eddie, Pearlman, Kenneth S., Richards, Christopher T., Stein-Spencer, Leslee, Tataris, Katie L., Weber, Joseph M., Zaidi, Hashim Q.   +7 more
core   +1 more source

The effect of midazolam dose and age on the paradoxical midazolam reaction in Korean pediatric patients [PDF]

Korean Journal of Anesthesiology, 2013
BackgroundAlthough midazolam administration may occasionally induce a paradoxical episode, such as threatened crying and violent behavior in children, systematic studies on the causes of paradoxical reaction are limited.
Young Hee Shin, Myung Hee Kim, Jung Jin Lee, Soo Joo Choi, Mi Sook Gwak, Ae Ryoung Lee, Mi Na Park, Hyo Sung Joo, Jung Hee Choi   +8 more
doaj   +1 more source

Midazolam impedes lung carcinoma cell proliferation and migration via EGFR/MEK/ERK signaling pathway

Open Medicine, 2023
Non-small-cell lung cancer (NSCLC) is a dominating type of lung cancer with high morbidity and mortality. Midazolam has been reported to promote cell apoptosis in NSCLC, but the molecular mechanism of midazolam remains to be further explored.
Zhang Xiangchao, Han Zhe, Li Zhengjun, Wang Tao   +3 more
doaj   +1 more source

Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study. [PDF]

, 2020
Determining factors that contribute to interindividual and intra-individual variability in pharmacokinetics (PKs) and drug metabolism is essential for the optimal use of drugs in humans.
Alhaja, Maher, Dorrestein, Pieter C, Jarmusch, Alan K, Knight, Rob, Liyanage, Marlon, Ma, Joseph D, Momper, Jeremiah D, Tsunoda, Shirley M, Vrbanac, Alison   +8 more
core   +1 more source