Results 1 to 10 of about 58,995 (146)

Efficacy of remimazolam versus midazolam for procedural sedation: post hoc integrated analyses of three phase 3 clinical trials

Endoscopy International Open, 2022
Background and study aims Remimazolam is an ultra-short acting, fast onset/fast offset benzodiazepine for intravenous use in procedural sedation, general anesthesia, and Intensive Care Unit sedation.
Van-Anh Dao, Frank Schippers, Thomas Stöhr   +2 more
doaj   +1 more source

Avoiding the incompatibility of peripheral parenteral nutrition solution and midazolam injection for intravenous sedation

Fujita Medical Journal, 2021
Objectives: We have observed white turbidity when a midazolam injection is administered from a lateral tube during the administration of a peripheral parenteral nutrition (PPN) solution. The aim of the current study was to determine how to avoid compound
Akihiko Futamura, Takashi Higashiguchi, Takeshi Chihara, Yuka Yokota, Yoshinori Itani   +4 more
doaj   +1 more source

Perbedaan Waktu Pulih Sadar Anestesi Umum Sevofluran dengan Premedikasi Midazolam dan tanpa Premedikasi Midazolam

Jurnal Anestesi Perioperatif, 2022
Pemberian premedikasi midazolam memberikan efek sedasi yang panjang sehingga menimbulkan pulih sadar yang lebih lama. Tujuan penelitian ini adalah mengetahui perbedaan waktu pulih sadar anestesi umum sevofluran dengan dan tanpa premedikasi midazolam ...
Purwoko Purwoko, Ardana Tri Arianto, Djoko Tjahyo Nugroho   +2 more
doaj   +1 more source

Inflammation and cardiovascular status impact midazolam pharmacokinetics in critically ill children: An observational, prospective, controlled study

Pharmacology Research & Perspectives, 2022
Altered physiology caused by critical illness may change midazolam pharmacokinetics and thereby result in adverse reactions and outcomes in this vulnerable patient population.
Bikalpa Neupane, Hitesh Pandya, Tej Pandya, Rupert Austin, Neil Spooner, James Rudge, Hussain Mulla   +6 more
doaj   +1 more source

The effect of midazolam dose and age on the paradoxical midazolam reaction in Korean pediatric patients [PDF]

Korean Journal of Anesthesiology, 2013
BackgroundAlthough midazolam administration may occasionally induce a paradoxical episode, such as threatened crying and violent behavior in children, systematic studies on the causes of paradoxical reaction are limited.
Young Hee Shin, Myung Hee Kim, Jung Jin Lee, Soo Joo Choi, Mi Sook Gwak, Ae Ryoung Lee, Mi Na Park, Hyo Sung Joo, Jung Hee Choi   +8 more
doaj   +1 more source

Midazolam impedes lung carcinoma cell proliferation and migration via EGFR/MEK/ERK signaling pathway

Open Medicine, 2023
Non-small-cell lung cancer (NSCLC) is a dominating type of lung cancer with high morbidity and mortality. Midazolam has been reported to promote cell apoptosis in NSCLC, but the molecular mechanism of midazolam remains to be further explored.
Zhang Xiangchao, Han Zhe, Li Zhengjun, Wang Tao   +3 more
doaj   +1 more source

Midazolam impacts acetyl-And butyrylcholinesterase genes: An epigenetic explanation for postoperative delirium?

PLoS ONE, 2022
Midazolam is a widely used short-acting benzodiazepine. However, midazolam is also criticized for its deliriogenic potential. Since delirium is associated with a malfunction of the neurotransmitter acetylcholine, midazolam appears to interfere with its ...
Katharina Rump, Caroline Holtkamp, Lars Bergmann, Hartmuth Nowak, Matthias Unterberg, Jennifer Orlowski, Patrick Thon, Zainab Bazzi, Maha Bazzi, Michael Adamzik, Björn Koos, Tim Rahmel   +11 more
doaj   +1 more source

Effect of sedative premedication with oral midazolam on postanesthesia care unit delirium in older adults: a secondary analysis following an uncontrolled before-after design

Perioperative Medicine, 2022
Background Sedative premedication with benzodiazepines has been linked with prolonged recovery and inadequate emergence during the immediate postoperative period.
Karin Stuff, Elena Kainz, Ursula Kahl, Hans Pinnschmidt, Stefanie Beck, Franziska von Breunig, Rainer Nitzschke, Sandra Funcke, Christian Zöllner, Marlene Fischer   +9 more
doaj   +1 more source

Individual differences in the effects of midazolam on anxiety-like behavior, learning, reward, and choice behavior in male mice

Frontiers in Psychiatry, 2023
IntroductionThe aim of the present study was to investigate the behavioral effects of the benzodiazepine midazolam in male mice, in models of anxiolysis, learning, and abuse-related effects.MethodsIn a first set of experiments, male Swiss mice were ...
Caio Jovita-Farias, Meagan E. Follett, Behaim C. Dias-Junior, Yasmim A. Serra, Natali D. Kisaki, Thaísa Barros-Santos, Nailton M. S. de Jesus, Isa R. S. Rodrigues, Larissa E. L. Macedo, Elena L. A. Malpezzi-Marinho, Alexandre J. Oliveira-Lima, Eduardo Ary Villela Marinho, James K. Rowlett, Lais F. Berro, Lais F. Berro   +14 more
doaj   +1 more source

Prescription drug forms with midazolam [PDF]

Farmacja Polska, 2021
Midazolam is a benzodiazepine derivative. It is characterized by a short half-life. It has a strong sedative, anxiolytic and hypnotic effect. It also acts as an anticonvulsant and relaxes skeletal muscles.
Anna Czech, Renata Jachowicz
doaj   +1 more source