Results 31 to 40 of about 125,004 (342)

Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency [PDF]

, 2010
Objective: Patients with congenital adrenal hyperplasia due to P450 oxidoreductase (POR) deficiency(ORD) present with disordered sex development and glucocorticoid deficiency.
Arlt, Bebia, Chang, de Morais, Dominique Maiter, Dorota Tomalik-Scharte, Fl  ck, Fuhr, Gomes, Hannah E Ivison, Henderson, Jetter, Julia Kirchheiner, Kelley, Kirchheiner, Kranendonk, Nebert, Nicolo, Parkinson, Porter, Ribes, Sachse, Tantcheva-Po  r, Tomalik-Scharte, Uwe Fuhr, Wiebke Arlt   +25 more
core   +2 more sources

Midazolam for sedation before procedures in adults and children: a systematic review update

Systematic Reviews, 2021
Background Midazolam is used for sedation before diagnostic and therapeutic medical procedures by several routes including oral, intravenous, intranasal and intramuscular. This is an update of a Cochrane review published in 2016, which aimed to determine
Aaron Conway, Kristina Chang, Sebastian Mafeld, Joanna Sutherland   +3 more
doaj   +1 more source

The influence of DNA polymorphism of multidrug resistant 1 (MDR1) on the effect of midazolam pretreatment in children [PDF]

Korean Journal of Anesthesiology, 2012
BackgroundPatients showed a different response following intravenous midazolam injection. Some children showed irritability or were not sedated by midazolam.
Hyo-Jin Byon, Keun-Suk Park, Yong-Hee Park, Jin-Tae Kim, Chul-Woo Jung, Hee-Soo Kim   +5 more
doaj   +1 more source

Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication. [PDF]

, 2017
A key goal of diabetes research is to develop treatments to safely promote human ß-cell replication. It has recently become appreciated that activation of γ-aminobutyric acid receptors (GABA-Rs) on ß-cells can promote their survival and replication.
Dang, Hoa, Kaufman, Daniel L, Middleton, Blake, Tian, Jide   +3 more
core   +1 more source

Postoperative expressive aphasia associated with intravenous midazolam administration: a 5-year retrospective case-control study

Journal of International Medical Research, 2020
Objectives This study aimed to investigate the epidemiology of intravenous midazolam-induced postoperative expressive aphasia (EA). Methods The incidence rate, risk ratio, and contributing factors to intravenous midazolam-induced postoperative EA were ...
Saecheol Oh, Jihyun Chung, Sujin Baek, Yoo Jung Park   +3 more
doaj   +1 more source

Posttraumatic midazolam administration does not influence brain damage after experimental traumatic brain injury

BMC Anesthesiology, 2022
Background The benzodiazepine midazolam is a γ-aminobutyric acid (GABA)-A receptor agonist frequently used for sedation or stress control in patients suffering from traumatic brain injury (TBI).
Anne Sebastiani, Simone Bender, Michael K. E. Schäfer, Serge C. Thal   +3 more
doaj   +1 more source

Vocal learning promotes patterned inhibitory connectivity. [PDF]

, 2017
Skill learning is instantiated by changes to functional connectivity within premotor circuits, but whether the specificity of learning depends on structured changes to inhibitory circuitry remains unclear.
Brainard, Michael S, Cheung, Chung Yan J, Miller, Mark N   +2 more
core   +2 more sources

A method for measuring the molecular ratio of inhalation to exhalation and effect of inspired oxygen levels on oxygen consumption

Scientific Reports, 2021
Using a new method for measuring the molecular ratio (R) of inhalation to exhalation, we investigated the effect of high fraction of inspired oxygen (FIO2) on oxygen consumption (VO2), carbon dioxide generation (VCO2), and respiratory quotient (RQ) in ...
Koichiro Shinozaki, Yu Okuma, Kota Saeki, Santiago J. Miyara, Tomoaki Aoki, Ernesto P. Molmenti, Tai Yin, Junhwan Kim, Joshua W. Lampe, Lance B. Becker   +9 more
doaj   +1 more source

Alcohol Withdrawal – Therapeutical Management in Surgical Patients with Upper Intestinal Bleeding [PDF]

, 2015
Psychological dependence involves a desire to use a drug to avoid the unpleasant withdrawal syndrome that results from cessation of exposure to it. Alcohol withdrawal syndrome is one of the most feared complications of alcohol addiction and sometimes can
Bogdan, Popescu, Cristian, Bălălău, Denisa, Cobani Oana, Gloria, Trambitasu, Negrei, Carolina, Valentin, Scăunașu Răzvan   +5 more
core   +4 more sources

Neuromuscular Blockade with Rocuronium Bromide Increases the Tolerance of Acute Normovolemic Anemia in Anesthetized Pigs [PDF]

, 2012
Background: The patient's individual anemia tolerance is pivotal when blood transfusions become necessary, but are not feasible for some reason. To date, the effects of neuromuscular blockade (NMB) on anemia tolerance have not been investigated. Methods:
A. Pape, B. Zwissler, Barton RG, Cain SM, Eisenberg E, Fontana JL, H. Kertscho, Habler OP, Haller M, Herweling A, Holt JP, Ickx BE, Kampe S, Kemming GI, Kim J, Koskolou MD, Levy PS, M. Lossen, Madjdpour C, Marik PE, McCall M, Meier J, Meier JM, Meier JM, Meier JM, Meisner FG, Messmer KF, Muldoon SM, Naguib M, O. Habler, O. Horn, P. Stein, Pape A, Pape A, Pape A, Perez V, Pittman RN, Richardson RS, Russell WC, S. Kutschker, Schumacker PT, van der Linden P, van der Linden P, van Woerkens EC, Vernon DD, Werlhof V, Zollinger A   +46 more
core   +1 more source