Results 41 to 50 of about 152,722 (386)

The influence of DNA polymorphism of multidrug resistant 1 (MDR1) on the effect of midazolam pretreatment in children [PDF]

Korean Journal of Anesthesiology, 2012
BackgroundPatients showed a different response following intravenous midazolam injection. Some children showed irritability or were not sedated by midazolam.
Hyo-Jin Byon, Keun-Suk Park, Yong-Hee Park, Jin-Tae Kim, Chul-Woo Jung, Hee-Soo Kim   +5 more
doaj   +1 more source

Midazolam and Dexmedetomidine Affect Neuroglioma and Lung Carcinoma Cell Biology In Vitro and In Vivo

Anesthesiology, 2018
What We Already Know about This Topic Dexmedetomidine reduces cellular apoptosis, and it has been demonstrated previously that this antiapoptotic effect can not only increase cancer cell proliferation and migration but also reduce survival in ...
Chunyan Wang, Tanweer Datoo, Hailin Zhao, Lingzhi Wu, A. Date, Cui Jiang, R. Sanders, Guolin Wang, C. Bevan, D. Ma   +9 more
semanticscholar   +1 more source

Postoperative expressive aphasia associated with intravenous midazolam administration: a 5-year retrospective case-control study

Journal of International Medical Research, 2020
Objectives This study aimed to investigate the epidemiology of intravenous midazolam-induced postoperative expressive aphasia (EA). Methods The incidence rate, risk ratio, and contributing factors to intravenous midazolam-induced postoperative EA were ...
Saecheol Oh, Jihyun Chung, Sujin Baek, Yoo Jung Park   +3 more
doaj   +1 more source

Premedication with midazolam in intellectually disabled dental patients: intramuscular or oral administration? A retrospective study [PDF]

, 2016
Background: The use of midazolam for dental care in patients with intellectual disability is poorly documented. The purpose of this study was to determine which method of premedication is more effective for these patients, 0.15 mg/kg of intramuscular ...
Boku, Aiji, Hanamoto, Hiroshi, Inoue, Mika, Niwa, Hitoshi, Oyamaguchi, Aiko, Sugimura, Mitsutaka   +5 more
core   +1 more source

Midazolam-Resistant Seizures and Brain Injury after Acute Intoxication of Diisopropylfluorophosphate, an Organophosphate Pesticide and Surrogate for Nerve Agents

Journal of Pharmacology and Experimental Therapeutics, 2018
Organophosphates (OP) such as the pesticide diisopropylfluorophosphate (DFP) and the nerve agent sarin are lethal chemicals that induce seizures, status epilepticus (SE), and brain damage.
Xin Wu, Ramkumar Kuruba, D. Reddy
semanticscholar   +1 more source

The Antinociceptive Effects of Midazolam on Three Different Types of Nociception in Mice

Journal of Pharmacological Sciences, 2009
Antinociceptive effects of systemically administered midazolam remain controversial. The present study was performed to investigate its antinociceptive effects on different types of nociception in mice. Four different doses of midazolam (1, 3, 10, and 30
Shunsuke Chiba, Tomoki Nishiyama, Masanobu Yoshikawa, Yoshitsugu Yamada   +3 more
doaj   +1 more source

Posttraumatic midazolam administration does not influence brain damage after experimental traumatic brain injury

BMC Anesthesiology, 2022
Background The benzodiazepine midazolam is a γ-aminobutyric acid (GABA)-A receptor agonist frequently used for sedation or stress control in patients suffering from traumatic brain injury (TBI).
Anne Sebastiani, Simone Bender, Michael K. E. Schäfer, Serge C. Thal   +3 more
doaj   +1 more source

Characterization of porcine hepatic and intestinal drug metabolizing CYP450 : comparison with human orthologues from a quantitative, activity and selectivity perspective [PDF]

, 2019
Over the past two decades, the pig has gained attention as a potential model for human drug metabolism. Cytochrome P450 enzymes (CYP450), a superfamily of biotransformation enzymes, are pivotal in drug metabolism.
Croubels, Siska, De Clerck, Laura, Deforce, Dieter, Devreese, Mathias, Govaert, Elisabeth, Millecam, Joske, Schelstraete, Wim, Van Bocxlaer, Jan   +7 more
core   +1 more source

A method for measuring the molecular ratio of inhalation to exhalation and effect of inspired oxygen levels on oxygen consumption

Scientific Reports, 2021
Using a new method for measuring the molecular ratio (R) of inhalation to exhalation, we investigated the effect of high fraction of inspired oxygen (FIO2) on oxygen consumption (VO2), carbon dioxide generation (VCO2), and respiratory quotient (RQ) in ...
Koichiro Shinozaki, Yu Okuma, Kota Saeki, Santiago J. Miyara, Tomoaki Aoki, Ernesto P. Molmenti, Tai Yin, Junhwan Kim, Joshua W. Lampe, Lance B. Becker   +9 more
doaj   +1 more source

Neuromuscular Blockade with Rocuronium Bromide Increases the Tolerance of Acute Normovolemic Anemia in Anesthetized Pigs [PDF]

, 2012
Background: The patient's individual anemia tolerance is pivotal when blood transfusions become necessary, but are not feasible for some reason. To date, the effects of neuromuscular blockade (NMB) on anemia tolerance have not been investigated. Methods:
A. Pape, B. Zwissler, Barton RG, Cain SM, Eisenberg E, Fontana JL, H. Kertscho, Habler OP, Haller M, Herweling A, Holt JP, Ickx BE, Kampe S, Kemming GI, Kim J, Koskolou MD, Levy PS, M. Lossen, Madjdpour C, Marik PE, McCall M, Meier J, Meier JM, Meier JM, Meier JM, Meisner FG, Messmer KF, Muldoon SM, Naguib M, O. Habler, O. Horn, P. Stein, Pape A, Pape A, Pape A, Perez V, Pittman RN, Richardson RS, Russell WC, S. Kutschker, Schumacker PT, van der Linden P, van der Linden P, van Woerkens EC, Vernon DD, Werlhof V, Zollinger A   +46 more
core   +1 more source