Results 41 to 50 of about 151,098 (403)
Dexmedetomidine versus Midazolam in Procedural Sedation. A Systematic Review of Efficacy and Safety
PLoS ONE, 2017 Objectives To systematically review the literature comparing the efficacy and safety of dexmedetomidine and midazolam when used for procedural sedation.
C. Barends +4 more
semanticscholar +1 more source
Vocal learning promotes patterned inhibitory connectivity. [PDF]
, 2017 Skill learning is instantiated by changes to functional connectivity within premotor circuits, but whether the specificity of learning depends on structured changes to inhibitory circuitry remains unclear.
Brainard, Michael S +2 more
core +2 more sources
Clinically applicable GABA receptor positive allosteric modulators promote ß-cell replication. [PDF]
, 2017 A key goal of diabetes research is to develop treatments to safely promote human ß-cell replication. It has recently become appreciated that activation of γ-aminobutyric acid receptors (GABA-Rs) on ß-cells can promote their survival and replication.
Dang, Hoa +3 more
core +1 more source
Anesthesiology, 2018 What We Already Know about This Topic Dexmedetomidine reduces cellular apoptosis, and it has been demonstrated previously that this antiapoptotic effect can not only increase cancer cell proliferation and migration but also reduce survival in ...
Chunyan Wang +9 more
semanticscholar +1 more source
The influence of DNA polymorphism of multidrug resistant 1 (MDR1) on the effect of midazolam pretreatment in children [PDF]
Korean Journal of Anesthesiology, 2012 BackgroundPatients showed a different response following intravenous midazolam injection. Some children showed irritability or were not sedated by midazolam.
Hyo-Jin Byon +5 more
doaj +1 more source
Journal of Pain and Symptom Management, 2002 Significant distress is experienced by patients, families, and caregivers when a symptom or disorder, such as an agitated delirium, becomes an intractable, or a catastrophic event, such as irreversible stridor. When palliative sedation is indicated for these patients, midazolam is usually the preferred drug.
Célia Roemer-Becuwe +2 more
openaire +2 more sources
Journal of Pharmacology and Experimental Therapeutics, 2018 Organophosphates (OP) such as the pesticide diisopropylfluorophosphate (DFP) and the nerve agent sarin are lethal chemicals that induce seizures, status epilepticus (SE), and brain damage.
Xin Wu, Ramkumar Kuruba, D. Reddy
semanticscholar +1 more source
Impaired hepatic drug and steroid metabolism in congenital adrenal hyperplasia due to P450 oxidoreductase deficiency [PDF]
, 2010 Objective: Patients with congenital adrenal hyperplasia due to P450 oxidoreductase (POR) deficiency(ORD) present with disordered sex development and glucocorticoid deficiency.
Arlt +25 more
core +2 more sources
A Case of Midazolam Anaphylaxis
Clinical Endoscopy, 2014 Midazolam is a type of anesthetic agent frequently used for conscious sedation during a variety of medical procedures. Anaphylactic reactions to midazolam are rarely reported. However, we observed a case of midazolam hypersensitivity in which emergency measures were required to ensure patient recovery after administration of midazolam as a sedative ...
Jae Gyu Shin +7 more
openaire +3 more sources
BMC Anesthesiology, 2022 Background The benzodiazepine midazolam is a γ-aminobutyric acid (GABA)-A receptor agonist frequently used for sedation or stress control in patients suffering from traumatic brain injury (TBI).
Anne Sebastiani +3 more
doaj +1 more source