Results 31 to 40 of about 173,798 (309)

Sequential Role of SOXB2 Factors in GABAergic Neuron Specification of the Dorsal Midbrain

Frontiers in Molecular Neuroscience, 2018
Studies proposed a model for embryonic neurogenesis where the expression levels of the SOXB2 and SOXB1 factors regulate the differentiation status of the neural stem cells. However, the precise role of the SOXB2 genes remains controversial.
Neoklis Makrides, Elena Panayiotou, Pavlos Fanis, Christos Karaiskos, George Lapathitis, Stavros Malas   +5 more
doaj   +1 more source

Increased Macrophages and C1qA, C3, C4 Transcripts in the Midbrain of People With Schizophrenia

Frontiers in Immunology, 2020
Increased cytokine and inflammatory-related transcripts are found in the ventral midbrain, a dopamine neuron-rich region associated with schizophrenia symptoms.
Tertia D. Purves-Tyson, Tertia D. Purves-Tyson, Kate Robinson, Amelia M. Brown, Danny Boerrigter, Helen Q. Cai, Helen Q. Cai, Christin Weissleder, Samantha J. Owens, Debora A. Rothmond, Cynthia Shannon Weickert, Cynthia Shannon Weickert, Cynthia Shannon Weickert   +12 more
doaj   +1 more source

Transcriptomics reveal an integrative role for maternal thyroid hormones during zebrafish embryogenesis [PDF]

, 2017
Thyroid hormones (THs) are essential for embryonic brain development but the genetic mechanisms involved in the action of maternal THs (MTHs) are still largely unknown.
A Tallafuss, AC Lekven, AC Lekven, ALS Dowling, AP Halestrap, AV Gore, B Langmead, C Schuurmans, C Trapnell, CB Kimmel, CC Thompson, CM Armour, D Croft, D Lopez-Espindola, D Zada, DM Power, E Vrieze de, ECH Friesema, ECH Friesema, ECH Friesema, F Boukhtouche, F Chatonnet, F Chatonnet, F Supek, FJ Arjona, GD Vatine, GO Consortium, GR Williams, H Dong, H Gao, H Heuer, H Iwayama, J Bernal, J Chang, J Delbaere, J Jin, J Patel, J Schindelin, JJ Essner, JJ Essner, K Wallis, KR Holden, L Boccone, LA Desouza, MA Campinho, MA Campinho, MD Robinson, MF Batista, PC Holm, RB MacDonald, RS Dezonne, RT Zoeller, RT Zoeller, S Bertrand, S Horn, S Kersseboom, S Mayerl, S Skah, S-X Wu, T Pierfelice, VM Darras, VW Edward, Y Katsuyama, Y-C Cheng   +63 more
core   +2 more sources

Vibrissal midbrain loops

Scholarpedia, 2011
The midbrain consists of the tectum and the tegmentum. The tectum comprises the inferior colliculus and superior colliculus. The tegmentum contains several areas including the periaqueductal gray, mesencephalic reticular formation (aka, deep mesencephalic nucleus), cuneiform nucleus (also commonly referred in rodents as deep mesencephalic nucleus ...
Manuel Castro-Alamancos, Asaf Keller
openaire   +2 more sources

Morphometry MRI in the differential diagnosis of parkinsonian syndromes Morfometria por ressonância magnética no diagnóstico diferencial das síndromes parkinsonianas

Arquivos de Neuro-Psiquiatria, 2010
This study evaluates the diagnostic value of morphometric magnetic resonance imaging (MRI) in the differential diagnosis among Parkinson's disease (PD), progressive supranuclear palsy (PSP) and multiple system atrophy (MSA).
Rômulo L Gama, Daniel F.G Távora, Rodrigo C Bomfim, Cruiff E Silva, Veralice M. de Bruin, Pedro F. de Bruin   +5 more
doaj   +1 more source

A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids

eLife, 2020
Three-dimensional (3D) culture systems have fueled hopes to bring about the next generation of more physiologically relevant high-throughput screens (HTS).
Henrik Renner, Martha Grabos, Katharina J Becker, Theresa E Kagermeier, Jie Wu, Mandy Otto, Stefan Peischard, Dagmar Zeuschner, Yaroslav TsyTsyura, Paul Disse, Jürgen Klingauf, Sebastian A Leidel, Guiscard Seebohm, Hans R Schöler, Jan M Bruder   +14 more
doaj   +1 more source

Mapping the Shh long-range regulatory domain [PDF]

, 2014
Coordinated gene expression controlled by long-distance enhancers is orchestrated by DNA regulatory sequences involving transcription factors and layers of control mechanisms.
Amano, Belloni, Bickmore, Chuong, Davis, Dixon, Echelard, Epstein, Hecksher-Sorensen, Jeong, Jeong, Klopocki, Kokubu, Lettice, Lettice, Lettice, Lettice, Lettice, Lettice, Liu, Marinić, Mates, Montavon, Nagy, Niedermaier, Osoegawa, Paek, Riddle, Ruf, Sagai, Sagai, Sagai, Sharpe, Sharpe, Shen, Smallwood, Spitz, Sun, Symmons, Symmons, The ENCODE Consortium Project, Tsukiji   +41 more
core   +2 more sources

IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells

Stem Cell Reports, 2017
Human pluripotent stem cell (hPSC)-derived mesencephalic dopaminergic (mesDA) neurons can relieve motor deficits in animal models of Parkinson's disease (PD).
Daniela Lehnen, Serena Barral, Tiago Cardoso, Shane Grealish, Andreas Heuer, Andrej Smiyakin, Agnete Kirkeby, Jutta Kollet, Harold Cremer, Malin Parmar, Andreas Bosio, Sebastian Knöbel   +11 more
doaj   +1 more source

Essential role for PDGF signaling in ophthalmic trigeminal placode induction [PDF]

, 2008
Much of the peripheral nervous system of the head is derived from ectodermal thickenings, called placodes, that delaminate or invaginate to form cranial ganglia and sense organs.
Bronner-Fraser, Marianne, McCabe, Kathryn L.   +1 more
core   +1 more source

Midbrain vasculitic aneurysms [PDF]

Neurology, 2004
This 16-year-old girl had a muscle biopsy demonstrating vasculitis seven years ago when she presented with weakness and Raynaud’s phenomenon (figure, B). Aside from occasional unexplained abdominal pain and chronic anemia, she had been well until one year ago, …
Hyung-Min, Kwon, Jae-Kyu, Roh, Gregory Youngnam, Chang   +2 more
openaire   +2 more sources