Results 11 to 20 of about 122,656 (259)

Temporal-spatial changes in Sonic Hedgehog expression and signaling reveal different potentials of ventral mesencephalic progenitors to populate distinct ventral midbrain nuclei [PDF]

open access: yes, 2011
Background: The ventral midbrain contains a diverse array of neurons, including dopaminergic neurons of the ventral tegmental area (VTA) and substantia nigra (SN) and neurons of the red nucleus (RN).
Joyner, Alexandra L.   +33 more
core   +1 more source

Immediate early gene expression in the mesopontine tegmentum and midbrain after acute or chronic nicotine administration [PDF]

open access: yes, 2008
The reinforcing properties of nicotine depend partly on cholinergic projections from the pedunculopontine tegmental (PPTg) and laterodorsal tegmental (LDTg) nuclei to midbrain dopamine neurons in the ventral tegmental area (VTA) and substantia nigra pars
Porter, Ailsa
core   +2 more sources

Perineuronal Nets and GABAergic cells in the Inferior Colliculus of Guinea Pigs

open access: yesFrontiers in Neuroanatomy, 2014
Perineuronal nets (PNs) are aggregates of extracellular matrix that have been associated with neuronal plasticity, critical periods, fast-spiking cells and protection from oxidative stress.
Nichole L Foster   +4 more
doaj   +1 more source

Sex-specific disruption of murine midbrain astrocytic and dopaminergic developmental trajectories following antenatal GC treatment [PDF]

open access: yes, 2015
The mammalian midbrain dopaminergic systems arising in the substantia nigra pars compacta (SNc) and ventral tegmental area (VTA) are critical for coping behaviours and are implicated in neuropsychiatric disorders where early life challenges comprise ...
Pienaar, Ilse   +18 more
core   +2 more sources

Sensory prediction errors in the human midbrain signal identity violations independent of perceptual distance

open access: yeseLife, 2019
The firing of dopaminergic midbrain neurons is thought to reflect prediction errors (PE) that depend on the difference between the value of expected and received rewards.
Javier A Suarez   +3 more
doaj   +1 more source

Mesencephalic basolateral domain specification is dependent on Sonic Hedgehog

open access: yesFrontiers in Neuroanatomy, 2015
In the study of central nervous system morphogenesis, the identification of new molecular markers allows us to identify domains along the antero-posterior and dorso-ventral axes.
Jesus E. Martinez-Lopez   +5 more
doaj   +1 more source

Leptin and Insulin Signaling in Dopaminergic Neurons: Relationship between Energy Balance and Reward System

open access: yesFrontiers in Psychology, 2014
The central actions of leptin and insulin are essential for the regulation of energy and glucose homeostasis. In addition to the crucial effects on the hypothalamus, emerging evidence suggests that the leptin and insulin signaling can act on other brain ...
V. Khanh eDoan   +4 more
doaj   +1 more source

PiacentinoLab/2021-Essential-function-and-targets-of-BMP-signaling-during-midbrain-neural-crest-delamination: DOI Release

open access: yes, 2023
Code and source data pertaining to Piacentino et al., 2021: Transcriptome profiling reveals BMP target genes during midbrain neural crest ...
Mike Piacentino
core   +1 more source

Neurosensory development of the four brainstem-projecting sensory systems and their integration in the telencephalon

open access: yesFrontiers in Neural Circuits, 2022
Somatosensory, taste, vestibular, and auditory information is first processed in the brainstem. From the brainstem, the respective information is relayed to specific regions within the cortex, where these inputs are further processed and integrated with ...
Bernd Fritzsch   +3 more
doaj   +1 more source

Palmitate and Stearate are Increased in the Plasma in a 6-OHDA Model of Parkinson’s Disease

open access: yesMetabolites, 2019
Introduction: Parkinson’s disease (PD) is the second most common neurodegenerative disorder, without any widely available curative therapy. Metabolomics is a powerful tool which can be used to identify unexpected pathway-related disease progression
Anuri Shah   +4 more
doaj   +1 more source

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